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Search Results (972)

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Keywords = fracture fixation

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14 pages, 3809 KB  
Article
Postoperative Complications Following Open Reduction and Internal Fixation of Mandibular Condylar Fractures Using the High Perimandibular Approach: A Multicenter Retrospective Study
by Noriko Sakata, Masako Fujioka-Kobayashi, Yuhei Matsuda, Reon Morioka, Erina Toda, Shinji Ishizuka, Michitaka Somoto, Rie Sonoyama-Osako, Hiroto Tatsumi and Takahiro Kanno
Craniomaxillofac. Trauma Reconstr. 2025, 18(4), 47; https://doi.org/10.3390/cmtr18040047 (registering DOI) - 25 Oct 2025
Viewed by 79
Abstract
Background: The high perimandibular approach (HPA) is a feasible surgical technique for open reduction and internal fixation (OR-IF) of mandibular condylar fractures, offering reduced complication rates. In this study, we retrospectively evaluated the treatment outcomes and complications associated with HPA use. Patients and [...] Read more.
Background: The high perimandibular approach (HPA) is a feasible surgical technique for open reduction and internal fixation (OR-IF) of mandibular condylar fractures, offering reduced complication rates. In this study, we retrospectively evaluated the treatment outcomes and complications associated with HPA use. Patients and Methods: Patients who underwent OR-IF for mandibular condylar fractures using the HPA at three hospitals in Shimane between June 2019 and March 2024 were included. Data collected included the mechanism of injury, AO classification of the fracture site, fracture type and mode, surgical duration, mouth-opening range at 6 months post-operatively, and peri- and post-operative complications. Results: A total of 42 patients (46 condylar fractures; 18 males and 24 females; mean age, 63.0 years) were included. The fracture pattern included dislocations in 18 cases (42.8%). The mean surgical duration was 75.0 min. Post-operative trismus occurred in 16 patients (38.1%) at 6 months. Longer surgical duration and dislocated fractures were significantly associated with post-operative trismus (p < 0.05). Conclusions: The HPA is safe and effective for managing mandibular condylar fractures. However, post-operative trismus may be influenced by longer surgical duration and fracture types, warranting further investigation and potential post-surgical management. Full article
(This article belongs to the Special Issue Advances in Facial Trauma Surgery)
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26 pages, 3537 KB  
Systematic Review
Sacral and Pelvic Insufficiency Fractures Following Adult Spinal Deformity Surgery: A Case Report and Systematic Literature Review
by Calogero Velluto, Achille Marciano, Gianmarco Vavalle, Maria Ilaria Borruto, Andrea Perna, Laura Scaramuzzo and Luca Proietti
J. Clin. Med. 2025, 14(21), 7572; https://doi.org/10.3390/jcm14217572 (registering DOI) - 25 Oct 2025
Viewed by 118
Abstract
Background: Sacral and pelvic insufficiency fractures (SIFs and PIFs) are increasingly recognized yet frequently underdiagnosed complications after adult spinal deformity (ASD) surgery, particularly in patients undergoing long-segment spinal fusion to the sacrum or pelvis. Methods: We present a representative case of [...] Read more.
Background: Sacral and pelvic insufficiency fractures (SIFs and PIFs) are increasingly recognized yet frequently underdiagnosed complications after adult spinal deformity (ASD) surgery, particularly in patients undergoing long-segment spinal fusion to the sacrum or pelvis. Methods: We present a representative case of sacral and pelvic insufficiency fractures following extensive spinal fusion, highlighting diagnostic and therapeutic challenges. In addition, a systematic review of the literature was performed according to PRISMA guidelines through PubMed, MEDLINE, and Scopus databases, including studies up to December 2024. Data regarding demographics, risk factors, diagnostic modalities, management strategies, and outcomes were extracted and narratively synthesized. Results: A total of 21 studies comprising 89 patients were included. The majority were elderly postmenopausal women with osteoporosis and additional risk factors such as chronic corticosteroid therapy or high body mass index. Diagnosis was frequently delayed due to low sensitivity of plain radiographs, whereas computed tomography was the most reliable modality. Management was surgical in 49 patients (55%)—most commonly extension of fixation to the pelvis or use of S2-alar-iliac screws—with favorable fracture healing reported in most cases. Conservative treatment, employed in 40 patients (45%), included bracing, restricted activity, and bone health optimization, also leading to healing in the majority of cases. Conclusions: Sacral and pelvic insufficiency fractures represent an underrecognized but clinically significant complication after ASD surgery. Early recognition through cross-sectional imaging (CT/MRI) is crucial, and both surgical and conservative approaches can be effective if tailored to patient and fracture characteristics. Full article
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15 pages, 904 KB  
Article
Treatment Strategies for Isolated LC-1 Pelvic Injuries: A Comparative Cohort Study of Percutaneous Posterior-Only vs. Combined Anterior–Posterior Fixation
by Mohammed Rashed Aly Abdelrahman, Frank Hildebrand, Eftychios Bolierakis, Till Berk and Hatem Alabdulrahman
J. Clin. Med. 2025, 14(21), 7507; https://doi.org/10.3390/jcm14217507 - 23 Oct 2025
Viewed by 332
Abstract
Background: The management of lateral compression type 1 (LC-1) pelvic fractures remains controversial. Posterior fixation alone has traditionally been practiced without clearly defined indications for supplementary anterior stabilization. Direct comparative evidence between posterior-only and combined anterior–posterior fixation remains scarce. This study evaluated whether [...] Read more.
Background: The management of lateral compression type 1 (LC-1) pelvic fractures remains controversial. Posterior fixation alone has traditionally been practiced without clearly defined indications for supplementary anterior stabilization. Direct comparative evidence between posterior-only and combined anterior–posterior fixation remains scarce. This study evaluated whether institutional criteria reliably identify patients who benefit from additional percutaneous anterior fixation. Methods: A retrospective cohort study was conducted at a level I trauma center and included adults with LC-1 fractures treated exclusively by percutaneous fixation. Combined anterior–posterior fixation was performed when predominant anterior pain and radiographic compromise indicated instability. Primary outcomes were pain trajectory (Numeric Rating Scale), inpatient opioid use, physiotherapy clearance, and ward mobility. Results: Thirty-seven patients were analyzed (combined = 14; posterior-only = 23). Preoperative pain was higher in the combined group (median 7 vs. 6; median difference 1 [95% CI 0 to 2]; p = 0.0036). Postoperatively, pain scores were lower in the combined group at 1–6 weeks (median difference −1 [95% CI −2 to 0]; p < 0.05). Opioid consumption was reduced (193 mg vs. 312 mg; median difference −200 mg [95% CI −280 to −120]; p < 0.001), and physiotherapy clearance occurred earlier (4 vs. 7 days; median difference −3 [95% CI −5 to −1]; p = 0.020). Conclusion: Our current indications to perform combined fixation were associated with favorable early outcomes in pain control and physiotherapy clearance among patients with LC-1 fractures showing anterior compromise. These results support a selective combined approach, though interpretation must remain cautious given the small retrospective cohort. Further prospective studies are warranted to validate these findings and refine patient selection. Full article
(This article belongs to the Special Issue Orthopedic Trauma: Diagnosis, Treatment and Rehabilitation)
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22 pages, 3004 KB  
Article
Comparative Biomechanical Evaluation of Bicortical Screw Versus Plate Fixation in Jones Fractures of the Fifth Metatarsal Using 3D-Printed Models
by Robert Daniel Dobrotă, Mark Pogărășteanu, Dumitru Ferechide, Ioana-Codruța Lebada and Marius Moga
J. Clin. Med. 2025, 14(20), 7449; https://doi.org/10.3390/jcm14207449 - 21 Oct 2025
Viewed by 224
Abstract
Background: Jones fractures of the 5th metatarsal are frequently associated with nonunion due to limited vascularization and repetitive mechanical stress. The aim of the study was to compare the biomechanical performance of T-plate and bicortical screw fixation using standardized 3D models. Methods: Three-dimensional [...] Read more.
Background: Jones fractures of the 5th metatarsal are frequently associated with nonunion due to limited vascularization and repetitive mechanical stress. The aim of the study was to compare the biomechanical performance of T-plate and bicortical screw fixation using standardized 3D models. Methods: Three-dimensional models of the 5th metatarsal were generated from CT images and printed using PolyJet technology (Stratasys J5 DentaJet) using a rigid-elastic composite with properties similar to cortical and cancellous bone. Jones fractures were fixed with either a locked T-plate or a bicortical screw. The samples were tested under axial and oblique static loads (α = 0°, 90°, 180°) and for three values of interfragmentary distance (d = 0.1–1 mm), in a 3 × 2 factorial design. Results: The T-plate fixation recorded a maximum yield force (Fmax) of 149.78 ± 8.53 N (138–161 N), significantly higher compared to the bicortical screw −98.56 ± 2.58 N (96–101 N), (p < 0.05). The ductility index was higher for the plate, indicating a progressive transition to yield. The α and d factors significantly influenced the mechanical behavior, with the polynomial model explaining over 95% of the total variation. Discussion: The plate fixation demonstrated greater strength and superior biomechanical tolerance in imperfect reduction scenarios. The main limitation is the lack of fatigue testing and the inability of 3D models to reproduce the structural heterogeneity of human bone. Conclusions: Implant selection should be individualized based on fracture stability. 3D models provide a reproducible platform for comparative evaluation of osteosynthesis methods, but future studies should include cyclic loading and biological validation. Full article
(This article belongs to the Section Orthopedics)
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19 pages, 4904 KB  
Article
Room-Temperature Superplasticity in a Biodegradable Zn-0.1Mg Alloy
by Karel Saksl, Róbert Kočiško, Patrik Petroušek, Miloš Matvija, Martin Fujda, Dávid Csík, Zuzana Molčanová, Beáta Ballóková, Iryna Cuperová, Katarína Gáborová, Maksym Lisnichuk, Miloslav Lupták and Adam Lupták
Metals 2025, 15(10), 1161; https://doi.org/10.3390/met15101161 - 21 Oct 2025
Viewed by 163
Abstract
Biodegradable zinc-based alloys have recently emerged as promising candidates for temporary biomedical implants due to their favorable biocompatibility, appropriate degradation rate, and relatively simple processing. In this study, the Zn-0.1Mg alloy was investigated after being processed by means of a two-step equal-channel angular [...] Read more.
Biodegradable zinc-based alloys have recently emerged as promising candidates for temporary biomedical implants due to their favorable biocompatibility, appropriate degradation rate, and relatively simple processing. In this study, the Zn-0.1Mg alloy was investigated after being processed by means of a two-step equal-channel angular pressing (ECAP) route, consisting of the first pass at 150 °C followed by a second pass at room temperature. The mechanical properties were evaluated using uniaxial tensile tests at different strain rates, while the microstructure and phase composition were analyzed using synchrotron hard X-ray diffraction and transmission electron microscopy (TEM). The processed alloy exhibited a remarkable enhancement in both strength and ductility compared to the annealed state. At the lowest applied strain rate, a fracture elongation of up to 240% was achieved at room temperature, representing a unique manifestation of superplasticity under ambient conditions. Diffraction analysis confirmed the stability of the supersaturated Zn matrix with minor Mg2Zn11 intermetallic phase. TEM observations revealed an ultrafine-grained microstructure and activation of non-basal slip systems, which enabled efficient plastic flow. These findings demonstrate that controlled severe plastic deformation provides an effective pathway for tailoring Zn-Mg alloys, opening opportunities for their use in the next generation of bioresorbable low-to-moderate load orthopedic fixation devices, e.g., plates, screws, suture anchors and craniofacial miniplates. Full article
(This article belongs to the Special Issue The Forming Behaviour and Plasticity of Metallic Alloys)
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11 pages, 1114 KB  
Article
Locking Plate with Cerclage Wiring Versus Hook Plate Fixation for Unstable Distal Clavicle Fractures: Is There Still a Role for Hook Plates?
by Hyun Seok Song and Hyungsuk Kim
Medicina 2025, 61(10), 1882; https://doi.org/10.3390/medicina61101882 - 21 Oct 2025
Viewed by 219
Abstract
Background and Objectives: Hook plate fixation has been widely used for unstable distal clavicle fractures, but concerns remain regarding implant-related complications and the need for secondary removal. Locking plate fixation with supplementary cerclage wiring has been proposed as an alternative that may [...] Read more.
Background and Objectives: Hook plate fixation has been widely used for unstable distal clavicle fractures, but concerns remain regarding implant-related complications and the need for secondary removal. Locking plate fixation with supplementary cerclage wiring has been proposed as an alternative that may provide stability while reducing complications. This study compared the clinical and radiologic outcomes of locking plate fixation with cerclage wiring versus hook plate fixation. Materials and Methods: A retrospective review was performed on patients who underwent open reduction and internal fixation for unstable distal clavicle fractures (Cho’s classification type II) between 2015 and 2024. Patients with at least 6 months of follow-up were included. Two techniques were evaluated: locking plate with cerclage wiring (Group 1) and hook plate fixation (Group 2). Clinical outcomes, including complications, range of motion, and patient satisfaction, were compared at the final follow-up. Results: A total of 52 patients met the inclusion criteria: 27 in Group 1 and 25 in Group 2. The overall mean follow-up period was 13.17 ± 8.46 months. The distribution of fracture types was not significantly different between groups (p = 0.287). Complications were more frequent in Group 2 (40%), including postoperative stiffness requiring capsular release (70%), nonunion requiring revision (20%), and peri-implant fracture (10%). The overall union rate was 100% in Group 1 and 80% in Group 2. In contrast, Group 1 had only one complication (3.7%), a peri-implant fracture (p = 0.002). Shoulder range of motion at the final follow-up showed no significant difference between groups. Conclusions: Hook plate fixation was associated with a significantly higher complication rate compared with locking plate fixation with cerclage wiring. Locking plate fixation with supplementary cerclage wiring appears to be a better surgical option for unstable distal clavicle fractures. Full article
(This article belongs to the Special Issue Orthopedic Trauma: Surgical Treatment and Rehabilitation)
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9 pages, 951 KB  
Article
Clinical Outcomes of Transdiscal Screws for Thoracolumbar Spinal Fractures with Marked Anterior Distraction Gap Accompanied by Diffuse Idiopathic Skeletal Hyperostosis
by Ryo Ugawa, Yoshihiro Fujiwara and Toshiyuki Matsumoto
Medicina 2025, 61(10), 1874; https://doi.org/10.3390/medicina61101874 - 19 Oct 2025
Viewed by 202
Abstract
Background and Objectives: Diffuse idiopathic skeletal hyperostosis (DISH)-related spinal fractures with marked anterior distraction are highly unstable and pose substantial surgical challenges. The transdiscal screw for diffuse idiopathic skeletal hyperostosis (TSD) technique has been proposed to enhance fixation strength by penetrating adjacent [...] Read more.
Background and Objectives: Diffuse idiopathic skeletal hyperostosis (DISH)-related spinal fractures with marked anterior distraction are highly unstable and pose substantial surgical challenges. The transdiscal screw for diffuse idiopathic skeletal hyperostosis (TSD) technique has been proposed to enhance fixation strength by penetrating adjacent vertebral endplates; however, its clinical utility in large-displacement cases remained unclear. Materials and Methods: In this retrospective study, we reviewed 21 patients with thoracolumbar DISH-related fractures and an anterior fracture gap ≥ 15 mm, who underwent posterior fixation between 2010 and 2024. 11 patients underwent TSD fixation (TSD group), and 10 underwent conventional fixation without bilateral TSD (control group). Results: The mean number of fused segments did not differ significantly between the groups (5.0 ± 1.4 vs. 5.0 ± 1.3, p = 0.43). Operative time was comparable (164 ± 57 vs. 168 ± 60 min, p = 0.90). Blood loss tended to be lower in the TSD group (306 ± 334 vs. 528 ± 658 mL, p = 0.33). For fracture-gap reduction, the TSD group improved from 17.4 ± 2.3 mm preoperatively to 13.8 ± 4.4 mm postoperatively and 2.0 ± 3.6 mm at final follow-up, while the control group showed less reduction (16.8 ± 2.2, 15.4 ± 1.4, and 7.0 ± 9.1 mm, respectively). Screw loosening occurred in three TSD patients and six controls (p = 0.13). All patients in the TSD group achieved bone union without reoperation, whereas four controls experienced implant backout, three required reoperation, and two failed to achieve bone union (p = 0.035). Conclusions: Posterior fixation using TSD provided reliable stability, maintained reduction, and reduced the risk of implant failure compared with conventional fixation in highly unstable DISH-related fractures with anterior distraction. Although larger prospective studies are needed, TSD may represent a valuable surgical option for this challenging patient population. Full article
(This article belongs to the Special Issue Spinal Surgery: Advances and Concerns)
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16 pages, 8480 KB  
Review
The Radiologists’ Guide to Spinal Separation Surgery: What Does the Surgeon Want to Know?
by Mohsin Khan, Labeeba Haq, Sai Niharika Gavvala, Petr Rehousek, Simon Hughes and Rajesh Botchu
Diseases 2025, 13(10), 348; https://doi.org/10.3390/diseases13100348 - 18 Oct 2025
Viewed by 279
Abstract
Spinal tumours are an uncommon but significant cause of pain, fractures, instability, and cord compression, leading to poor quality of life and mortality. Separation surgery is a rapidly advancing technique that has seen increased utilisation in the field of spinal oncology surgery. Separation [...] Read more.
Spinal tumours are an uncommon but significant cause of pain, fractures, instability, and cord compression, leading to poor quality of life and mortality. Separation surgery is a rapidly advancing technique that has seen increased utilisation in the field of spinal oncology surgery. Separation surgery can be described as a resection technique that decompresses the spinal cord whilst creating an ablative target for high-dose stereotactic radiotherapy to achieve durable local control while minimising the risk of radiation myelopathy. This has facilitated the delivery of stereotactic radiotherapy, as well as created potential for use in managing primary bone tumours of the spine. From a radiology standpoint, optimal outcomes depend on meticulous preoperative characterisation of tumour volume and stability (e.g., ESCC grade and SINS), clear communication of anatomic constraints relevant to approach and fixation, and systematic postoperative surveillance to distinguish expected postoperative appearances from early recurrence or complications. We present our radiological experience and report recommendations while evaluating spinal oncology separation surgery. Full article
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14 pages, 4148 KB  
Article
Plate Breakage After Mandibular Condylar Fracture Osteosynthesis
by Marcin Kozakiewicz, Paulina Agier and Paulina Pruszyńska
J. Funct. Biomater. 2025, 16(10), 389; https://doi.org/10.3390/jfb16100389 - 16 Oct 2025
Viewed by 757
Abstract
Despite the significant ongoing development of fixation materials, plate breakages still occur after osteosynthesis of the mandibular condyles. The aim of this study is to demonstrate the complications caused by fixation material breakages in the hope of inspiring the development of new, more [...] Read more.
Despite the significant ongoing development of fixation materials, plate breakages still occur after osteosynthesis of the mandibular condyles. The aim of this study is to demonstrate the complications caused by fixation material breakages in the hope of inspiring the development of new, more durable plates; we analyzed a total of 238 plates used for osteosynthesis in this anatomical region. Cases where compression screws were used as the sole fixation material were excluded. Plate breakage was found in six cases, which accounted for 2.52% of treated individuals. It seems that most plate breakages can be avoided by maintaining effective patient supervision for up to 6 months after surgery. Risk factors for breakage are identified and guidelines for improving the design of future plates are provided. By analyzing some plate design features, we provide some indications for improving their strength and improving their designs for use in this field. Full article
(This article belongs to the Special Issue Advances in Oral and Maxillofacial Implants)
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11 pages, 5491 KB  
Article
A Minimally Invasive Fixation Versus Double Plating of Associated Posterior Malleolus and Fibula Fractures—A Comparative Human Cadaveric Biomechanical Study
by Konstantin Ganchev, Preslav Penev, Ivan Zderic, Kajetan Klos, R. Geoff Richards, Dimitar Raykov, Boyko Gueorguiev, Lionel Llano and Karl Stoffel
Medicina 2025, 61(10), 1847; https://doi.org/10.3390/medicina61101847 - 15 Oct 2025
Viewed by 227
Abstract
Background and Objectives: Ankle fractures are common and occur in up to 25% of cases with posterior malleolus (PM) involvement. The gold standard for their treatment considers posterior approaches and plating of both the PM and fibula. However, in elderly and comorbid patients, [...] Read more.
Background and Objectives: Ankle fractures are common and occur in up to 25% of cases with posterior malleolus (PM) involvement. The gold standard for their treatment considers posterior approaches and plating of both the PM and fibula. However, in elderly and comorbid patients, this strategy remains controversial. The objective of this biomechanical study was to compare a minimally invasive fixation—utilizing a fibula nail and percutaneous anteroposterior (AP) screws—versus double plating. Materials and Methods: An oblique fibula fracture associated with a Haraguchi type 1 PM fracture was reproduced in sixteen human cadaveric specimens randomized to two groups. Eight specimens were treated with a fibula nail plus two AP screws fixing the PM, while the remaining eight specimens underwent double plating. Biomechanical testing was performed under destructive complex cyclic loading applying a staircase protocol. Interfragmentary movements were captured via motion tracking. Results: Initial axial stiffness was similar between nailing (1125.9 ± 341.7 N/mm) and double plating (742.9 ± 600.1 N/mm) (p = 0.129). During cyclic testing, interfragmentary fibula displacement was higher for double plating versus nailing (p = 0.057), whereas PM displacement and syndesmosis diastasis remained comparable between the two techniques (p ≥ 0.197). Conclusions: The minimally invasive fixation of associated PM and fibula fractures utilizing a fibula nail and two anteroposterior screws demonstrated non-inferiority to double plating and presents a viable option in cases where delicate soft tissue management is required. Full article
(This article belongs to the Section Orthopedics)
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17 pages, 362 KB  
Review
The Role of Kirschner Wires in Foot and Ankle Surgery: A Comprehensive Review and Practical Appraisal of Applications, Benefits, and Challenges
by Alberto Arceri, Antonio Mazzotti, Simone Ottavio Zielli, Laura Langone, Federico Sgubbi, Gianmarco Di Paola, Giuseppe D’Antonio and Cesare Faldini
Medicina 2025, 61(10), 1836; https://doi.org/10.3390/medicina61101836 - 14 Oct 2025
Viewed by 434
Abstract
Kirschner wires (K-wires) have remained an integral part of orthopedic surgery for decades, particularly in the management of foot and ankle pathologies. This review examines the role of K-wires by analyzing the applications in fracture fixation and deformity correction, highlighting advantages such as [...] Read more.
Kirschner wires (K-wires) have remained an integral part of orthopedic surgery for decades, particularly in the management of foot and ankle pathologies. This review examines the role of K-wires by analyzing the applications in fracture fixation and deformity correction, highlighting advantages such as cost-effectiveness and minimal soft-tissue disruption, while acknowledging limitations including lower torsional stability compared with rigid fixation and the risk of pin-tract infection. The purpose was to provide a comprehensive perspective on the clinical applications, advantages, and limitations of K-wires in contemporary surgical practice, with a focus on the most recent evidence from clinical studies. Full article
(This article belongs to the Section Orthopedics)
11 pages, 1018 KB  
Article
Routine Transposition or In Situ Decompression? Rethinking Ulnar Nerve Strategy in Distal Humerus Fractures
by Tahir Öztürk, Mete Gedikbaş, Fırat Erpala and Murat Aşçi
J. Clin. Med. 2025, 14(20), 7233; https://doi.org/10.3390/jcm14207233 - 14 Oct 2025
Viewed by 380
Abstract
Background: Fractures of the distal humerus (DHFs) represent challenging intra-articular injuries that are often followed by postoperative complications, most notably ulnar neuropathy. There is still debate regarding the best method of handling the ulnar nerve during open reduction and internal fixation (ORIF). [...] Read more.
Background: Fractures of the distal humerus (DHFs) represent challenging intra-articular injuries that are often followed by postoperative complications, most notably ulnar neuropathy. There is still debate regarding the best method of handling the ulnar nerve during open reduction and internal fixation (ORIF). Objective: The primary objective was to evaluate the incidence of postoperative ulnar neuropathy (UN) in patients who underwent open reduction and internal fixation (ORIF) for DHFs, comparing anterior transposition (AT) with in situ decompression (ISD) of the ulnar nerve. Additionally, we investigated the influence of AT on individuals presenting with preoperative UN. Methods: A retrospective review was conducted on 68 patients (26 females and 42 males; mean age: 46.3 years) who underwent ORIF for intra-articular DHF between 2018 and 2022. Patients were divided into two groups: anterior transposition (n = 14) and in situ decompression (n = 54). Ulnar neuropathy was evaluated using the modified McGowan classification, and radiographic outcomes were assessed with AO/OTA fracture classification. Results: Sixty-eight patients (26F/42M) were included. The mean age was 46.3 years (20–77 years) and the mean follow-up time was 53 months (36–76 months). The postoperative UN incidence was 30.8% (21/68). Neuropathy was significantly higher in the transposition group compared to in situ decompression (57.1% vs. 24%; p = 0.012). Olecranon osteotomy (36.3% vs. 20%; p = 0.042) and parallel plate configuration (33.3% vs. 12.5%; p = 0.037) were also associated with increased neuropathy risk. Among patients with preoperative ulnar neuropathy (n = 12), functional recovery was more favorable with transposition, where 71% experienced full resolution compared to 60% in the in situ group. Conclusions: Routine anterior transposition of the ulnar nerve during ORIF for DHF is associated with an increased risk of postoperative neuropathy and should be avoided in patients without preoperative symptoms. However, transposition appears beneficial in patients with pre-existing ulnar neuropathy. Surgeons should individualize ulnar nerve management to balance surgical risks and neurological outcomes. Full article
(This article belongs to the Section Orthopedics)
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13 pages, 2628 KB  
Case Report
Application of Novel Biomaterials to Enhance Bone Regeneration in a Canine Non-Union Olecranon Fracture
by Taeseok Noh, YoungJin Jeon, Se-Heang Oh, Sunglim Lee and Yoonho Roh
Animals 2025, 15(20), 2968; https://doi.org/10.3390/ani15202968 - 14 Oct 2025
Viewed by 386
Abstract
A six-year-old, neutered male Pomeranian weighing 4.25 kg was presented with a two-year history of non-weight-bearing lameness of the left thoracic limb following an untreated traumatic olecranon fracture. Orthopedic examination revealed markedly reduced elbow joint range of motion and muscle atrophy. Radiographs demonstrated [...] Read more.
A six-year-old, neutered male Pomeranian weighing 4.25 kg was presented with a two-year history of non-weight-bearing lameness of the left thoracic limb following an untreated traumatic olecranon fracture. Orthopedic examination revealed markedly reduced elbow joint range of motion and muscle atrophy. Radiographs demonstrated a distinct fracture line with proximolateral displacement of the olecranon fragment. Preoperative computed tomography (CT) and three-dimensional (3D) reconstruction were used to establish the surgical plan and to pre-contour a locking plate. Surgical treatment was performed in sequential steps, including removal of scar tissue, reopening of the bone marrow channel, and internal fixation. Considering the compromised biological environment of a chronic non-union, a bioactive graft composed of porous leaf-stacked structure (LSS) polycaprolactone particles incorporating recombinant human bone morphogenetic protein-2 (rhBMP-2) and mesenchymal stem cells (MSCs) was applied in combination with plate-screw fixation. The patient showed progressive improvement after surgery, achieving full weight-bearing and restoration of elbow joint motion comparable to the contralateral side. Follow-up radiographs and CT confirmed fracture union, and the radiolucency of the LSS scaffold enabled precise monitoring of bone healing. This case highlights the potential utility of combining patient-specific surgical planning with sustained delivery of rhBMP-2 and MSCs using LSS particles for the management of chronic non-union fractures in small animals. Full article
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26 pages, 4381 KB  
Article
Biocomposite-Based Biomimetic Plate for Alternative Fixation of Proximal Humerus Fractures
by Miguel Suffo, Irene Fernández-Illescas, Ana María Simonet, Celia Pérez-Muñoz and Pablo Andrés-Cano
Biomimetics 2025, 10(10), 688; https://doi.org/10.3390/biomimetics10100688 - 13 Oct 2025
Viewed by 529
Abstract
Proximal humerus fractures are frequent injuries that often require internal fixation. Conventional metallic plates, however, present significant drawbacks such as corrosion, secondary removal surgeries, and adverse reactions in patients with metal hypersensitivity. This study evaluates biocomposite plates fabricated from polylactic acid (PLA) and [...] Read more.
Proximal humerus fractures are frequent injuries that often require internal fixation. Conventional metallic plates, however, present significant drawbacks such as corrosion, secondary removal surgeries, and adverse reactions in patients with metal hypersensitivity. This study evaluates biocomposite plates fabricated from polylactic acid (PLA) and polyvinyl alcohol (PVA), reinforced with hydroxyapatite (HA) derived from sugar industry by-products (BCF) at 10% and 20% concentrations. These composites are compatible with both injection molding and 3D printing, enabling the design of patient-specific implants. Characterization by SEM, FTIR, XRD, and DSC confirmed that BCF incorporation enhances strength, stiffness, osteoconductivity, and biocompatibility. Mechanical testing showed that PVA/BCF exhibited greater tensile strength and stiffness, suggesting suitability for load-bearing applications, though their water solubility restricts use in humid environments and prevents filament-based 3D printing. PLA/BCF composites demonstrated better processability, favorable mechanical performance, and compatibility with both manufacturing routes. Finite element analysis highlighted the importance of plate–humerus contact in stress distribution and fixation stability. Compared with non-biodegradable thermoplastics such as PEI and PEEK, PLA/BCF and PVA/BCF offer the additional advantage of controlled biodegradation, reducing the need for secondary surgeries. Cell viability assays confirmed cytocompatibility, with optimal outcomes at 10% BCF in PVA and 20% in PLA. These results position PLA/BCF and PVA/BCF as sustainable, patient-tailored alternatives to metallic implants, combining adequate mechanical support with bone regeneration potential. Full article
(This article belongs to the Special Issue Biomimetic Materials for Bone Tissue Engineering)
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17 pages, 4247 KB  
Article
Endoscope-Assisted or Skin-Approach Osteosynthesis of Mandibular Condylar Fracture—A Comparison
by Paulina Agier, Dominik Szczeciński and Marcin Kozakiewicz
J. Funct. Biomater. 2025, 16(10), 382; https://doi.org/10.3390/jfb16100382 - 11 Oct 2025
Viewed by 674
Abstract
Open reduction and internal fixation (ORIF) for mandibular condyle fractures remains a controversial and challenging issue, with the exception of basal and low-neck fractures. Currently, there is a consensus that fractures causing irreparable malocclusion or dislocation, when the fracture line runs through the [...] Read more.
Open reduction and internal fixation (ORIF) for mandibular condyle fractures remains a controversial and challenging issue, with the exception of basal and low-neck fractures. Currently, there is a consensus that fractures causing irreparable malocclusion or dislocation, when the fracture line runs through the base or lower neck of the condyle, require ORIF. Due to the different characteristics of fractures, various surgical approaches and their modifications are available. The use of a minimally invasive intraoral approach during endoscope-assisted procedures is considered safer for the facial nerve and provides good esthetic results without facial scarring. This study aimed to compare two surgical approaches—retromandibular and intraoral—to examine post-operative outcomes and to guide surgical decision-making in the treatment of simple fractures of the base and low-neck condylar process of the mandible. Forty-nine patients (thirteen female, thirty-six male) were analyzed: eighteen were treated with the intraoral approach, and thirty-one with the retromandibular approach. There were no statistical differences in the duration of surgery, but intraoperative blood loss was significantly lower in patients treated endoscopically compared with those treated with an extraoral approach. Post-operative facial nerve and TMJ function were comparable in both groups. The endoscope-treated patients were at a higher risk of fracture non-union, but these findings should be considered with connection with the small sample size. The intraoral approach is a valuable option for basal or low-neck fractures but demands significant surgical experience due to its technical complexity. Full article
(This article belongs to the Special Issue Advanced Materials and Devices for Medical Interventions)
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