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18 pages, 1029 KiB  
Article
Processing Fruits and Vegetables as a Way to Prevent Their Waste
by Ksenia Juszczak-Szelągowska, Iwona Kowalczuk, Dawid Olewnicki, Małgorzata Kosicka-Gębska and Dagmara Stangierska-Mazurkiewicz
Sustainability 2025, 17(14), 6610; https://doi.org/10.3390/su17146610 - 19 Jul 2025
Viewed by 346
Abstract
The aim of the current study was to determine the scale and underlying causes for the waste of raw and processed fruits and vegetables in Polish households. A survey was conducted on a representative sample of 1100 respondents. The collected empirical data were [...] Read more.
The aim of the current study was to determine the scale and underlying causes for the waste of raw and processed fruits and vegetables in Polish households. A survey was conducted on a representative sample of 1100 respondents. The collected empirical data were analyzed using statistical tools such as non-parametric tests, multiple regression methods, and logistic regression. This study assessed the level and determinants of waste of raw and processed fruits and vegetables, identified the reasons for this waste and their impact on its extent, and analyzed the effect of waste prevention methods (including processing) on the scale of product losses. This study showed that the scale of waste of processed fruits and vegetables in Polish consumer households is significantly lower than that of raw products. The level of waste for both raw and processed products vary depending on place of residence, education, income, household size, and, in the case of processed fruits and vegetables, also the age of respondents. The main reason for fruit and vegetable losses in households is missing the product’s expiration date. Logistic regression analysis showed that the most effective strategies for reducing the waste of raw fruits and vegetables include purchasing the right quantities and freezing them. In contrast, practices such as donating food to others or composting were linked to a statistically significant decrease in the likelihood of reducing waste. Full article
(This article belongs to the Special Issue Future Trends in Food Processing and Food Preservation Techniques)
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15 pages, 28684 KiB  
Article
Efficient Expiration Date Recognition in Food Packages for Mobile Applications
by Hao Peng, Juan Bayon, Joaquin Recas and Maria Guijarro
Algorithms 2025, 18(5), 286; https://doi.org/10.3390/a18050286 - 15 May 2025
Viewed by 532
Abstract
The manuscript introduces an innovative framework for expiration date recognition aimed at improving accessibility for visually impaired individuals. The study underscores the pivotal role of convolutional neural networks (CNNs) in addressing complex challenges, such as variations in typography and image degradation. The system [...] Read more.
The manuscript introduces an innovative framework for expiration date recognition aimed at improving accessibility for visually impaired individuals. The study underscores the pivotal role of convolutional neural networks (CNNs) in addressing complex challenges, such as variations in typography and image degradation. The system attained an F1-score of 0.9303 for the detection task and an accuracy of 97.06% for the recognition model, with a total inference time of 63 milliseconds on a single GeForce GTX 1080 GPU. A comparative analysis of quantized models—FP32, FP16, and INT8—emphasizes the trade-offs in inference speed, energy efficiency, and accuracy on mobile devices. The experimental results indicate that the FP16 model operating in CPU mode achieves an optimal equilibrium between precision and energy consumption, underscoring its suitability for resource-constrained environments. Full article
(This article belongs to the Collection Feature Papers in Evolutionary Algorithms and Machine Learning)
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17 pages, 7919 KiB  
Article
Recycling Face Mask Fibers in Geopolymer-Based Matrices for Sustainable Building Materials
by Roberto Ercoli, Paola Stabile, Elena Ossoli, Irene Luconi, Alberto Renzulli and Eleonora Paris
Ceramics 2025, 8(2), 54; https://doi.org/10.3390/ceramics8020054 - 12 May 2025
Cited by 1 | Viewed by 928
Abstract
This study investigates the upcycling of disposable face masks, which were produced in vast quantities during the COVID-19 pandemic and are now widely stockpiled in public institutions, destined for landfills after reaching expiration dates. The research focuses on incorporating shredded mask fibers into [...] Read more.
This study investigates the upcycling of disposable face masks, which were produced in vast quantities during the COVID-19 pandemic and are now widely stockpiled in public institutions, destined for landfills after reaching expiration dates. The research focuses on incorporating shredded mask fibers into geopolymer matrices, evaluating the effects on mechanical and thermal properties to develop sustainable, high-performance materials. This approach addresses critical environmental, social, and economic challenges by transforming problematic waste into valuable resources while promoting sustainable building practices, such as developing insulating products for the construction industry. Mechanical testing demonstrated that adding shredded mask fibers (2 mm and 6 mm in size, up to 5 wt.%) enhanced the flexural strength of geopolymeric products. The optimal performance was achieved by adding 3 wt.% of 2 mm-length fibers, resulting in a flexural strength of 4.56 ± 0.23 MPa. Regarding compressive strength, the highest value (54.78 ± 2.08 MPa) was recorded in geopolymers containing 1 wt.% of 2 mm fibers. Thermal insulation properties of the materials improved with higher mask content, as evidenced by reductions in thermal conductivity, diffusivity, and specific heat. The lowest thermal conductivity values were observed in geopolymers containing 5 wt.% (0.4346 ± 0.0043 W·m−1·K−1) and 3 wt.% (0.6514 ± 0.0002 W·m−1·K−1) of 2 mm mask fibers. To further enhance thermal insulation, geopolymers with 5 wt.% mask fibers were foamed using H2O2 to obtain highly porous light materials, obtaining a reduction of thermal conductivity (0.3456 and 0.3710 ± 0.0007 W·m−1·K−1). This research highlights the potential of integrating fibrous waste materials into advanced construction technologies, offering solutions for waste reduction and development in the building sector toward sustainability. Full article
(This article belongs to the Special Issue The Production Processes and Applications of Geopolymers, 2nd Edition)
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8 pages, 372 KiB  
Data Descriptor
Dataset on Food Waste in Households: The Case of Latvia
by Ilze Beitane, Sandra Iriste, Martins Sabovics, Gita Krumina-Zemture and Janis Jenzis
Data 2025, 10(5), 65; https://doi.org/10.3390/data10050065 - 30 Apr 2025
Viewed by 483
Abstract
This publication presents raw data from an online survey in Latvia that reflects households’ practices, opinions, attitudes, and social responsibility regarding food waste. A total of 1336 respondents (households) participated in the survey. The questionnaire consisted of three parts, with the first part [...] Read more.
This publication presents raw data from an online survey in Latvia that reflects households’ practices, opinions, attitudes, and social responsibility regarding food waste. A total of 1336 respondents (households) participated in the survey. The questionnaire consisted of three parts, with the first part focusing on daily food habits and shopping habits, the second part focusing on respondents’ opinions and social responsibility on food waste management, and the third part containing questions on the frequency of shopping for different product groups. The dataset presented in the publication includes survey questions and response options, as well as raw survey data that can be used to compare households’ food waste behavior across countries. The data can help policy makers make data-driven decisions or serve as the basis for further research. Full article
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9 pages, 218 KiB  
Article
Synthetic Melatonin and/or Phytomelatonin Contents in Different Commercial Phytotherapeutic Supplements
by Ana Castejón-Castillejo, Josefa Hernández-Ruiz, Antonio Cano and Marino B. Arnao
Nutraceuticals 2025, 5(2), 9; https://doi.org/10.3390/nutraceuticals5020009 - 31 Mar 2025
Viewed by 1464
Abstract
In these times and with the pace of life that we have developed, many people need help falling asleep due to poor sleep hygiene, among other reasons. Thus, in mild cases, it is recommended to use natural therapies, such as phytotherapy, avoiding in [...] Read more.
In these times and with the pace of life that we have developed, many people need help falling asleep due to poor sleep hygiene, among other reasons. Thus, in mild cases, it is recommended to use natural therapies, such as phytotherapy, avoiding in the first instance the use of drugs. Melatonin is considered a versatile molecule widely used today. It is included as a main ingredient in dietary supplements that are, in some cases, accompanied by medicinal plants as botanical mixes, generating beneficial products for sleep disorders among other conditions. The dietary phytotherapeutic supplements evaluated in this work contain various concentrations of melatonin and other products, resulting in different effects on sleep therapy. The aim of this work is to reveal the quantitative differences that exist between the melatonin contents labeled in the products and those analyzed. The degradation rate of this hormone at three years in the phytotherapeutic supplements is also studied in order to re-evaluate the expiration dates of these products. In conclusion, the mixture between synthetic melatonin and different botanical mixes is very common in the supplements studied here and aimed at improving sleep. However, the most natural thing would be to be able to use only plants with sufficient phytomelatonin content to eliminate the inclusion of chemically synthesized melatonin in preparation. We propose the use of a particular raw plant material with excellent characteristics for this purpose. Full article
16 pages, 313 KiB  
Article
On the Četaev Condition for Nonholonomic Systems
by Federico Talamucci
AppliedMath 2025, 5(1), 29; https://doi.org/10.3390/appliedmath5010029 - 13 Mar 2025
Viewed by 537
Abstract
In the context of holonomic systems, the identification of virtual displacements is clear and consolidated. This provides the possibility, once the class of displacements have been coupled with Newton’s equations, for us to write the correct equations of motion. This method combines the [...] Read more.
In the context of holonomic systems, the identification of virtual displacements is clear and consolidated. This provides the possibility, once the class of displacements have been coupled with Newton’s equations, for us to write the correct equations of motion. This method combines the d’Alembert principle with Lagrange formalism. As far as nonholonomic systems are concerned, the conjecture that dates back to Cˇetaev actually defines a class of virtual displacements through which the d’Alembert–Lagrange method can be applied again. A great deal of literature is dedicated to the Cˇetaev rule from both the theoretical and experimental points of view. The absence of a rigorous (mathematical) validation of the rule inferable from the constraint equations has been declared to have expired in a recent publication; one of our objectives is to produce a critical comment on this stated result. Finally, we explore the role of the Cˇetaev condition within the significant class of nonholonomic homogeneous constraints. Full article
17 pages, 9339 KiB  
Article
Applying Chitosan-Based Films Enriched with Borago officinalis Extract for Active and Green Packaging of Fresh Rainbow Trout Fillets
by Alper Güngören, Yasin Akkemik, Enis Fuat Tufekci, Gökhan Zengin, Gizem Emre, Gulsah Gungoren, Yasemin Celik Altunoglu and Mehmet Cengiz Baloğlu
Foods 2025, 14(4), 639; https://doi.org/10.3390/foods14040639 - 14 Feb 2025
Viewed by 978
Abstract
This study aimed to apply chitosan (CS) coating films enriched with Borago officinalis extract to preserve fresh rainbow trout fillets. Extracts of B. officinalis were prepared using ethyl acetate, ethanol, water, and an ethanol-water mixture. These extracts were incorporated into chitosan coating films [...] Read more.
This study aimed to apply chitosan (CS) coating films enriched with Borago officinalis extract to preserve fresh rainbow trout fillets. Extracts of B. officinalis were prepared using ethyl acetate, ethanol, water, and an ethanol-water mixture. These extracts were incorporated into chitosan coating films at 0.5% and 1% (v/v) concentrations, and their antimicrobial activity and antioxidant abilities were investigated. CS films with borage extract in ethanol-water combination showed the highest antibacterial zone diameter (9.5 ± 2.1 mm) against Staphylococcus aureus. Based on its superior antimicrobial and antioxidant activity, the ethanol-water extract was selected for further film characterization, including moisture content, swelling degree, solubility, and color. The films were then tested for their effectiveness in preserving rainbow trout fillets stored at 7 ± 1 °C. The fish samples were divided into four groups: control, chitosan coating film, chitosan coating film with 0.5% B. officinalis extract, and chitosan coating film with 1% B. officinalis extract. Physicochemical, chemical, and microbiological analyses were conducted until fillet spoilage was observed (12 days). Results demonstrated that chitosan coating films enriched with 1% extract of B. officinalis prolonged the expiration date of the fish by six days, had significant antioxidant properties, and protected fish from discoloration. While the coating films demonstrated promising antioxidant properties and the shelf life extension of the fish samples by six days, further optimization will be required to enhance their antimicrobial effectiveness. Full article
(This article belongs to the Section Food Packaging and Preservation)
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22 pages, 522 KiB  
Article
Non-Maturing Deposits: Predictive Modelling and Risk Management
by Anton van Dyk
J. Risk Financial Manag. 2025, 18(2), 84; https://doi.org/10.3390/jrfm18020084 - 5 Feb 2025
Viewed by 2410
Abstract
Non-maturing deposits (NMDs) are a significant source of liquidity for banks, making research into their modelling and forecasting invaluable. However, NMDs have no explicit expiration date, posing liquidity risks and complicating management. This research develops models and a framework to explain, predict, and [...] Read more.
Non-maturing deposits (NMDs) are a significant source of liquidity for banks, making research into their modelling and forecasting invaluable. However, NMDs have no explicit expiration date, posing liquidity risks and complicating management. This research develops models and a framework to explain, predict, and manage variations in non-maturing deposits. Aggregate savings and transaction deposit data from an African bank were analysed to test the methodologies. The Trend-Fourier model, leveraging historical trends and Fourier analysis, forecasted 90-day deposit volumes. The model revealed prominent cyclicalities and monthly trends in deposit account volumes. Benchmarking showed high accuracy for savings deposit volumes, while transaction deposit volumes were less accurate, suggesting simpler models might be suitable. Additionally, a risk metric called LVaR (Liquidity Value at Risk) was proposed. Two approaches for calculating the LVaR were tested. An exceedance test demonstrated notable accuracy for savings deposit volumes but struggled with transaction deposits. Results indicated savings deposit volumes were more predictable than transaction deposits. These findings could enhance banks’ balance sheet management by improving non-maturing deposit forecasting. The proposed methodologies could be utilized for internal and regulatory purposes, such as calculating the liquidity coverage ratio under Basel regulations. Full article
(This article belongs to the Section Mathematics and Finance)
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53 pages, 2127 KiB  
Review
Technology Development in Online Grocery Shopping—From Shopping Services to Virtual Reality, Metaverse, and Smart Devices: A Review
by Kinga Stecuła, Radosław Wolniak and Barış Aydın
Foods 2024, 13(23), 3959; https://doi.org/10.3390/foods13233959 - 8 Dec 2024
Cited by 9 | Viewed by 10473
Abstract
This paper presents a review of the technologies and services associated with online grocery shopping. The progress in the field of online grocery shopping has been very rapid in recent years. Hence, there was a need to systematize knowledge about the latest various [...] Read more.
This paper presents a review of the technologies and services associated with online grocery shopping. The progress in the field of online grocery shopping has been very rapid in recent years. Hence, there was a need to systematize knowledge about the latest various solutions used in this topic. The authors searched the internet, focusing on websites of different supermarkets, shops, and other services that offer online shopping, as well as reviewed scientific papers. Based on the collected material, the authors created four thematic parts, which include: (1) supermarket services; (2) dedicated grocery delivery services and farm-to-table; (3) shopping in Virtual Reality and the metaverse; smart devices and (4) AI in food ordering—the last part includes smart devices, such as smart refrigerators, ovens, their functionality, and the services connected with them. The authors refer to 243 sources. The research includes the three following objectives: (1) exploring and presenting the emerging applied ways of online grocery shopping, (2) exploring and presenting the latest technological advances related to the digitalization of grocery shopping, (3) discussing the upcoming technologies, services, and methods in online grocery shopping. This paper provides knowledge about a wide range of solutions offered by both supermarkets and stores (e.g., shopping applications, VR applications, metaverse shopping) and other companies (e.g., deliveries, product tracking), highlighting the numerous functions available thanks to smart devices (e.g., voice control, own shopping lists, control of products, their quantities and expiration dates, management of user preferences, and many more). This paper also discusses social issues related to the presented solutions, such as their influence on consumer behavior, barriers to adoption, and the associated challenges. Full article
(This article belongs to the Special Issue Artificial Intelligence for the Food Industry)
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14 pages, 2844 KiB  
Article
Green and Eco-Friendly Egg White–TiO2 Hydrogel with Enhanced Antimicrobial, Adsorptive, and Photocatalytic Properties
by Mei Zhang and Xu Wang
Catalysts 2024, 14(12), 899; https://doi.org/10.3390/catal14120899 - 8 Dec 2024
Viewed by 1167
Abstract
The design of multi-purpose decontaminants with environmentally friendly characteristics, low cost, and high efficiency in removing pollutants from the environment is an effective and economic strategy for maintaining the long-term development of the ecosystem. Based on the strategy of killing two birds with [...] Read more.
The design of multi-purpose decontaminants with environmentally friendly characteristics, low cost, and high efficiency in removing pollutants from the environment is an effective and economic strategy for maintaining the long-term development of the ecosystem. Based on the strategy of killing two birds with one stone, an egg white (EW)/TiO2 hydrogel with a porous structure is devised as a bio-adsorbent using waste eggs nearing their expiration date for simultaneously achieving the efficient removal of organic dyes and the inactivation of microorganisms from industrial wastewater. The characterizations of its morphology and composition using scanning electron microscopy (SEM), the Brunauer–Emmett–Teller (BET) theory, energy-dispersive spectrometry (EDS), Fourier transform infrared spectroscopy (FTIR), and a thermogravimetric analyzer (TGA) validate the successful synthesis of EW/TiO2. The maximum adsorption capacity of EW/TiO2 is 333.172 mg∙mL−1 according to the Langmuir model. The photodegradation of a methyl blue (MB) solution under irradiation via a xenon lamp is used to assess the photocatalytic behavior of EW/TiO2. Among the different samples, the 5 wt% TiO2-doped EW/TiO2 hydrogel shows an efficiency of 99% for 120 min of irradiation. Finally, the antibacterial properties of the EW/TiO2 hydrogel are evaluated by calculating its bacterial survival rate against Escherichia coli (E. coli). The EW/TiO2 photocatalyst exhibits a photocatalytic inactivation efficiency of 90.4%, indicating that the EW/TiO2 hydrogel possesses positive antibacterial activity via effectively inhibiting the growth of the bacteria, which is suitable for industrial wastewater treatment over a long period of time. Full article
(This article belongs to the Special Issue Photocatalytic Nanomaterials for Environmental Purification)
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12 pages, 3349 KiB  
Communication
Accelerated Life Tests for Time-Dependent Response Characterization of Functionalized Piezoelectric Microcantilever-Based Gas Sensors
by Lawrence Nsubuga and Roana de Oliveira Hansen
Electronics 2024, 13(22), 4525; https://doi.org/10.3390/electronics13224525 - 18 Nov 2024
Cited by 1 | Viewed by 890
Abstract
This article explores the accelerated lifetime test approach to characterize the time-dependent response of a piezoelectrically driven microcantilever (PD-MC) based gas sensor. The novelty here relies on demonstrating how accelerated lifetime tests can be useful to differentiate sensing mechanisms for non-linear gas sensors. [...] Read more.
This article explores the accelerated lifetime test approach to characterize the time-dependent response of a piezoelectrically driven microcantilever (PD-MC) based gas sensor. The novelty here relies on demonstrating how accelerated lifetime tests can be useful to differentiate sensing mechanisms for non-linear gas sensors. The results show the determination of the sensor’s optimum operation time while maintaining result validity. The approach is demonstrated for 1,5-diaminopentane (cadaverine), a volatile organic compound (VOC) whose concentration in meat and fish products has been proven viable for determining the shelf life. A PD-MC functionalized with a cadaverine-specific binder was therefore incorporated into a hand-held electronic nose, and the response was found to be highly reliable within a specific resonance frequency shift, enabling the accurate prediction of meat and fish expiration dates. To identify the limits of detection in terms of cadaverine concentration and sensor lifetime, this study applies the results of accelerated life tests into a Weibull distribution analysis to extract the expected time to failure. For the accelerated life tests, a functionalized PD-MC was exposed to high concentrations of cadaverine, i.e., 252.3 mg/kg, 335.82 mg/kg, and 421.08 mg/kg, compared to the nominal concentration of 33 mg/kg observed in meat and fish samples. Furthermore, we demonstrate the differentiation of the response mechanisms of the system accruing from the concentration-dependent interaction of cadaverine with the binder. This enables the determination of the upper limit of the analyte concentration for a stable response. The findings suggest that the functionalized PD-MC sensor exhibits a linear and predictable response when exposed to a standard cadaverine concentration of 33 mg/kg for up to 93.01 min. Full article
(This article belongs to the Special Issue Electronic Nose: From Fundamental Research to Applications)
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12 pages, 243 KiB  
Commentary
Future Healthcare Workers and Ecopharmacovigilance: Where Do We Stand?
by Toni Durdov, Ana Šešelja Perišin, Nikolina Škaro, Josipa Bukić, Dario Leskur, Darko Modun, Joško Božić, Marjeta Grgas and Doris Rušić
Pharmacy 2024, 12(5), 146; https://doi.org/10.3390/pharmacy12050146 - 26 Sep 2024
Cited by 2 | Viewed by 1316
Abstract
With the rapid development of the pharmaceutical industry and constant growth of drug usage, ecopharmacovigilance (EPV) has emerged as a way of coping with and minimizing the effects that drugs have on the environment. EPV concerns and describes unwanted effects that the use [...] Read more.
With the rapid development of the pharmaceutical industry and constant growth of drug usage, ecopharmacovigilance (EPV) has emerged as a way of coping with and minimizing the effects that drugs have on the environment. EPV concerns and describes unwanted effects that the use of a specific drug could have on the environment. The US, EU and Cananda are the improving position of EPV, both in legislation and practice. EPV requires further development as previous studies have shown that neither the general population nor healthcare professionals have enough knowledge about the subject. Improving awareness and knowledge about this topic is a key task for the future of EPV. The main objective was to determine students’ level of knowledge about ecopharmacovigilance and to examine ways of storing and disposing of unused and expired drugs. Students’ knowledge and habits were examined by a previously published survey. The survey contains twenty questions divided into three parts and the possibility of writing an additional note. There was no difference in the level of knowledge between the students of different studies. Also, students who had a family member working as healthcare professional did not show a higher level of knowledge compared to the others. Pharmacy students had a greater intention to educate their environment about EPV when compared to students of the other studies. This is in the line with a previous study which showed that the general public expects that pharmacists and physicians educate them about EPV. Medicine and dental medicine students will become prescribers after finishing their studies, and as such, they should be informed about eco-directed sustainable prescribing (EDSP) as part of an EPV strategy. More than half of the participants reported good adherence to prescribers’ instruction, which decreased the amount of unused drugs. Most of the students found that the drug expiration date was legible, but they did not check it often. In comparison with similar studies, Croatian students had more knowledge and better practices concerning EPV and drug disposal. Structured learning strategies and curriculum implementation for EPV are much needed for further raising awareness about the subject among healthcare professionals and the public. Full article
5 pages, 366 KiB  
Brief Report
How Reproducible Is Feraheme® (Ferumoxytol Injection)? Comparison of Size, Zeta Potential, and Complement Activation of Different Batches over 15 Years
by Utibeabasi Ettah, Sarah Jacques and Dmitri Simberg
J. Nanotheranostics 2024, 5(3), 128-132; https://doi.org/10.3390/jnt5030009 - 3 Sep 2024
Viewed by 1922
Abstract
Ferumoxytol injection, also known as Feraheme®, is an approved IV injectable iron supplement and an experimental MRI contrast agent. Initially, it was approved as an IV bolus agent, but its use was later limited to a slow infusion drip due to [...] Read more.
Ferumoxytol injection, also known as Feraheme®, is an approved IV injectable iron supplement and an experimental MRI contrast agent. Initially, it was approved as an IV bolus agent, but its use was later limited to a slow infusion drip due to high levels of infusion reactions. We collected various batches of ferumoxytol with expiration dates ranging from 2010 to 2025 and compared their size and zeta potential. Since nanoparticle surface properties can affect infusion reactions, we conducted a dot blot immunoassay to measure complement C3 opsonization with ferumoxytol preparations. We observed differences in nanoparticle size and zeta potential between batches and a 2.5-fold variation in complement activation. Interestingly, older batches from 2010 showed more uniform size distribution and lower complement activation than some of the newer batches. This finding may be valuable to the nanomedicine community and regulatory authorities. Full article
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17 pages, 1295 KiB  
Review
Stability Preparedness: The Not-So-Cold Case for Innovations in Vaccine Stability Modelling and Product Release
by Franz Schnetzinger, Didier Clénet, Philippe-Alexandre Gilbert, Antonio Guzzi, Marilena Paludi, Jos Weusten and Renske Hesselink
Vaccines 2024, 12(9), 1000; https://doi.org/10.3390/vaccines12091000 - 1 Sep 2024
Cited by 3 | Viewed by 3995
Abstract
The rapid development of equitably accessible vaccines is paramount in addressing emerging global health challenges. The safety and efficacy of vaccines hinge significantly on their ability to remain stable from manufacturing throughout the supply chain and up to administration. Furthermore, the release of [...] Read more.
The rapid development of equitably accessible vaccines is paramount in addressing emerging global health challenges. The safety and efficacy of vaccines hinge significantly on their ability to remain stable from manufacturing throughout the supply chain and up to administration. Furthermore, the release of vaccines requires sufficient understanding of the stability profile to allow for expiration dating. In the event of a public health crisis, the time to generate the necessary stability data and the need for rapid product release are in direct opposition. Developing manufacturing platforms with thermostable product formulations for rapid response is therefore key to meeting CEPI’s 100 Days Mission goal. This Review aims to highlight the need for stability preparedness through developing thermostable vaccine platforms and exploring innovative stability monitoring strategies that leverage advanced technologies, predictive modelling, and adaptive methodologies. By doing so, we seek to enhance the efficiency and effectiveness of stability assessments, supporting rapid development, regulatory approval, and widespread, equal distribution of vaccines—especially in an outbreak scenario. Finally, enhanced thermostability will allow for simplification across the supply chain, which will reduce the financial burden of vaccination programmes and enhance equitable access. Full article
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15 pages, 1122 KiB  
Article
Development and Evaluation of Nutritional and Quality Standard of Beef Burger Supplemented with Pumpkin (Cucurbita moschata) Seed Flour
by Flávia Alexsandra B. Rolim de Melo, Maria Brígida Fonseca Galvão, Antônio Félix da Costa, Carla Fabiana da Silva, Jenyffer Medeiros Campos Guerra and Thayza Christina Montenegro Stamford
Foods 2024, 13(11), 1702; https://doi.org/10.3390/foods13111702 - 29 May 2024
Cited by 2 | Viewed by 2000
Abstract
The composition of pumpkin seeds includes bioactive compounds, proteins, polyunsaturated fatty acids, and dietary fibers. Thus, the objective of this research was to develop and evaluate the nutritional and quality standard of beef burgers supplemented with pumpkin seeds (Cucurbita moschata) added [...] Read more.
The composition of pumpkin seeds includes bioactive compounds, proteins, polyunsaturated fatty acids, and dietary fibers. Thus, the objective of this research was to develop and evaluate the nutritional and quality standard of beef burgers supplemented with pumpkin seeds (Cucurbita moschata) added in different proportions. To process the pumpkin seed flour (PSF), the seeds were sanitized, dried in an oven, crushed, and sieved. Through such means, three formulations of beef burgers were prepared, named S (without the addition of PSF), F5 (with the addition of 5% (w/w) of PSF), and F10 (with the addition of 10% (w/w) of PSF). The respective results for burgers P, F5, and F10 were as follows (w/w): proteins 17.61%, 18.04%, 19.86%; lipids 12.19%, 12.42%, 14.55%; ash 1.77%, 1.86%, 1.94%; fibers 0%, 0.88%, 1.76%; phenolic compounds 39.55, 82.93, 90.30 (mg/g); and total antioxidant capacity 11.09%, 18.48%, 24.45%. Regarding the sensory analysis attributes, tasters gave sample F10 scores lower than 7. However, the standard and F5 samples showed results higher than 7 for all parameters. For the determination of shelf life, an expiration date of 30 days was established. It was observed that adding PSF to industrialized products adds nutritional value with the inclusion of polyunsaturated fats, phenolic compounds, and dietary fibers. Full article
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