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Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking
- Laura González-Cofrade,
- Irene Cuadrado,
- Ángel Amesty,
- Ana Estévez-Braun,
- Beatriz de las Heras and
- Sonsoles Hortelano
Dehydroisohispanolone (DIH), is a labdane diterpene that has exhibited anti-inflammatory activity via inhibition of NF-κB activation, although its potential effects on inflammasome activation remain unexplored. This study aims to elucidate whet...