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19 pages, 1404 KB  
Article
Walking Towards the Energy Transition: An Approach to an International Cooperation Management Model for the Development of Renewable Energies in Cuba
by Mirel Alvarez, Miriam Lourdes Filgueiras, Anaely Saunders and Jesús Suárez
Sustainability 2026, 18(12), 6256; https://doi.org/10.3390/su18126256 - 17 Jun 2026
Viewed by 13
Abstract
Cuba is driving its sustainable energy transition with renewables as the central axis, although the Cuban government estimates that substantial investments will be necessary to achieve this goal. This work presents a proposal for a Management Model of International Cooperation for the Development [...] Read more.
Cuba is driving its sustainable energy transition with renewables as the central axis, although the Cuban government estimates that substantial investments will be necessary to achieve this goal. This work presents a proposal for a Management Model of International Cooperation for the Development of Renewable Energies, aimed at mobilizing the required funds. The model was designed through a structured questionnaire with 7 dimensions, 22 activities, and 5 subprocesses to guide the collaborative management of projects. The methodological approach was quantitative, descriptive, and psychometric, ensuring content validity through expert evaluation and statistical analysis. Reliability was established through internal consistency measures, while construct validity was supported by an exploratory factor analysis, confirming its feasibility and coherence. The validated questionnaire confirms its methodological rigor and practical utility, favoring the subsequent implementation of the model for Cuba’s transition toward green energy. Full article
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30 pages, 776 KB  
Article
Holistic Thermoenergetic Assessment of Biomass Boilers: An Integrated Static, Dynamic, and Emergy Framework
by Eladio Omar Cajusol Pingo, Yoisdel Castillo Alvarez, Reinier Jiménez Borges, Jonny Paul Zavala de Paz, Francisco Antonio Castillo Velasquez, Luis Angel Iturralde Carrera and Juvenal Rodríguez-Resendiz
Biomass 2026, 6(3), 46; https://doi.org/10.3390/biomass6030046 - 17 Jun 2026
Viewed by 67
Abstract
The evaluation of biomass boilers using partial approaches limits system understanding, because energy, exergy, dynamic, and emergy analyses describe complementary, but not equivalent, dimensions of thermo-industrial performance. In response to this gap, an integrated methodological framework is proposed to analyze two representative steam [...] Read more.
The evaluation of biomass boilers using partial approaches limits system understanding, because energy, exergy, dynamic, and emergy analyses describe complementary, but not equivalent, dimensions of thermo-industrial performance. In response to this gap, an integrated methodological framework is proposed to analyze two representative steam generator technologies in the sugar industry, fueled with ternary mixtures of sugarcane bagasse, Agricultural Crop Residues (ACR), and Dichrostachys cinerea, with the aim of identifying robust operating windows from a simultaneously thermal, exergetic, transient, and sustainability perspective. The methodology combines: (i) a direct and indirect steady-state model to quantify thermal losses and efficiency; (ii) an exergy model to assess conversion quality; (iii) a two-node coupled transient dynamic model capable of representing the differentiated response of the combustion zone and the water/steam system to moisture perturbations; and (iv) an emergy model to estimate the overall sustainability of the process. The results show that the effective moisture content of the mixture is the dominant control variable, since it determines the lower heating value on a wet basis, the specific fuel consumption, the main thermal loss, and the dynamic stability of the system. In the transient domain, a +5% step perturbation in moisture generates drops of 11.14–12.20 °C and 17.76–19.39 °C in furnace temperature for G1 and G2, respectively, while the steam response is damped to 1.03–1.14 °C and 2.39–2.65 °C. Likewise, moisture explains the magnitude of the response with coefficients of determination above 0.99, and the sensitivity analysis identifies the controller time constant, the thermal mass of the water/steam system, and the emissivity as the most influential parameters. Overall, the proposed framework makes it possible to go beyond isolated efficiency assessment and move toward a holistic characterization of biomass boiler performance under technically plausible ternary mixtures. Although the proposed methodological framework is transferable to other biomass combustion contexts, the numerical results—including optimal compositional zones, emergy indicators, and dynamic sensitivity coefficients—are specific to the Cuban sugar industry conditions, adopted transformities, and the biomass types evaluated herein. Full article
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16 pages, 1827 KB  
Article
Polymer Composition Provides Insights into Source- and Transport-Related Microplastic Patterns in Caribbean Coral Reef Environments
by Yusmila Helguera Pedraza, Nathalie Bernard, Ana Flavia Roldan Ramos, Dariadelys Reyes Noa, Joán I. Hernandez-Albernas, Anamary Acosta Valladares, Marco A. Garcia Varens, Arianna García Chamero, Marc Metian, Lorena Rios, Francois Oberhaensli and Carlos Alonso-Hernandez
Microplastics 2026, 5(2), 124; https://doi.org/10.3390/microplastics5020124 - 15 Jun 2026
Viewed by 86
Abstract
Microplastic contamination in coral reef environments is increasingly recognized as a global concern; however, the extent to which polymer composition can help distinguish contamination sources and transport-related processes remains poorly understood. In this study, we assessed the abundance, composition, and diversity of microplastics [...] Read more.
Microplastic contamination in coral reef environments is increasingly recognized as a global concern; however, the extent to which polymer composition can help distinguish contamination sources and transport-related processes remains poorly understood. In this study, we assessed the abundance, composition, and diversity of microplastics (20–300 µm) across multiple reef systems in the Cuban archipelago using high-resolution Laser Direct Infrared (LDIR) spectroscopic analysis. Microplastic abundance varied substantially among sites, with a median concentration of 66 particles L−1 (IQR: 45–115 particles L−1), ranging from 8 to 218 particles L−1. A total of 11 polymer types were identified, with polyethylene (PE), polypropylene (PP), and polyamide (PA) dominating the assemblages and accounting for approximately 77% of detected particles. While these polymers were consistently observed across all sites, suggesting a pervasive regional background signal, highly impacted reefs exhibited more heterogeneous polymer profiles, including increased contributions of polyurethane (PU), polytetrafluoroethylene (PTFE), and polyvinyl chloride (PVC), consistent with localized anthropogenic influence. Multivariate analysis revealed moderate compositional structuring among reef sites and suggested broad differences in polymer assemblages associated with contrasting contamination settings. Notably, some reefs exhibited elevated microplastic abundances while remaining dominated by common polymers, indicating a partial decoupling between contamination levels and polymer-specific signatures. This pattern is consistent with the influence of regional transport and mixing processes across the Caribbean basin, potentially including circulation associated with the Yucatán Channel, although hydrodynamic processes were not directly assessed in this study. Overall, the findings highlight the value of polymer-resolved analysis for improving interpretation of microplastic contamination patterns in coral reef environments. The integration of polymer composition with abundance and diversity metrics provides a useful framework for distinguishing between localized contamination signals and broader regional background influences. This study represents a regional baseline assessment of small microplastics in Caribbean coral reef systems using high-resolution spectroscopic characterization. Full article
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22 pages, 7500 KB  
Article
The Erased Filmmaker: Nicolás Guillén Landrián and the Politics of Censorship in Cuban Documentary Cinema
by Eliecer Jiménez Almeida and Santiago Juan-Navarro
Arts 2026, 15(6), 129; https://doi.org/10.3390/arts15060129 - 2 Jun 2026
Viewed by 506
Abstract
Nicolás Guillén Landrián (1938–2003) is often described as one of the most formally daring documentary filmmakers to emerge from Cuba’s Instituto Cubano del Arte e Industria Cinematográficos (ICAIC), yet decades of institutional censorship, including imprisonment, forced psychiatric treatment, and the quiet burial of [...] Read more.
Nicolás Guillén Landrián (1938–2003) is often described as one of the most formally daring documentary filmmakers to emerge from Cuba’s Instituto Cubano del Arte e Industria Cinematográficos (ICAIC), yet decades of institutional censorship, including imprisonment, forced psychiatric treatment, and the quiet burial of his films in archives, pushed him into a kind of official nonexistence. His work resurfaced unexpectedly during a 2003 screening in Havana, an event that seemed to reveal just how much had been missing from the historical record. This article examines the systematic relationship between the revolutionary Cuban censorship apparatus and the aesthetic strategies Guillén Landrián developed, from his early ICAIC shorts to his final exile film, Inside Downtown (2001). Drawing on archival materials, published interviews, critical theory (Foucault, Agamben, Bourdieu, Scott, de Certeau), and close readings of key films such as Coffea Arábiga (1968), Desde La Habana ¡1969! Recordar (1969–1971), and Taller de Línea y 18 (1971), we argue that censorship did not simply constrain his filmmaking but shaped it in ways that opened unexpected formal paths. We describe these strategies as a “poetics of obliqueness”—a mode of working that embeds critique within intermedial collage, uneasy juxtapositions, ellipsis, allegory, and double coding. These tactics exploited the gap between the apparatus’s strict monitoring of explicit ideological statements and its difficulty policing ambiguous or formally inventive gestures. Although grounded in the Cuban case, this framework speaks to broader questions about how artists under authoritarian conditions convert pressure into a generative constraint, revealing how creativity can survive, and sometimes mutate, under sustained surveillance. Full article
(This article belongs to the Special Issue Cinema and Censorship)
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23 pages, 1365 KB  
Article
Sparse Multivariate Analysis Reveals Dissociable White Matter Networks for Cognitive and Motor Processing Speed
by Shahwar Yasir, Nzamukiza Fidele, Eduardo Martinez-Montes, Lidice Galan-Garcia, Cheng Luo, Maria Luisa Bringas Vega and Pedro A. Valdes-Sosa
Brain Sci. 2026, 16(5), 533; https://doi.org/10.3390/brainsci16050533 - 19 May 2026
Viewed by 312
Abstract
Background: Reaction time (RT) is a fundamental measure of information processing speed in cognitive neuroscience and is influenced by both structural and functional brain properties. While prior studies have independently linked white matter microstructure and EEG alpha oscillations to cognitive performance, their joint [...] Read more.
Background: Reaction time (RT) is a fundamental measure of information processing speed in cognitive neuroscience and is influenced by both structural and functional brain properties. While prior studies have independently linked white matter microstructure and EEG alpha oscillations to cognitive performance, their joint contribution to distinct aspects of RT remains unclear. This study aims to investigate whether multimodal data can dissociate neural systems underlying cognitive and motor components of processing speed. Methods: We analyzed diffusion tensor imaging, resting-state individual EEG alpha peak frequency (IAF), demographic variables, and behavioral RT measures from a GO/NO-GO paradigm in 24 healthy adults from the Cuban Human Brain Mapping Project. Behavioral metrics included the mean, standard deviation and skewness of reaction times for simple and complex tasks. Sparse multiple canonical correlation analysis was applied to identify multivariate associations across modalities. Results: Two significant latent dimensions were identified. The first dimension linked bilateral fronto-temporal association tracts (SLF, IFOF, UNC) with complex RT performance, reflecting higher-order cognitive processing. The second dimension associated motor and interhemispheric tracts (CGC, CST, ILF, forceps major and minor) with intra-individual asymmetric variability (skewness) across tasks, indicating a motor-execution consistency system. IAF did not significantly contribute to either dimension. Sex showed strong associations with both components. Conclusions: Distinct white matter networks were associated with separable cognitive and motor aspects of processing speed, while resting-state alpha frequency did not show stable contributions with behavioral variability in this sample. IAF showed minimal contribution within the identified sparse multivariate dimensions. These findings highlight the importance of multimodal and multivariate approaches for understanding and potentially disentangling complex brain–behavior relationships. Full article
(This article belongs to the Section Neuropsychology)
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29 pages, 1664 KB  
Article
Quantum Kernels for Narrative Coherence: An Application to Path Optimization in Document Graphs for Storyline Extraction
by Brian Keith-Norambuena, Javiera Canales, Maximiliano Araya, Carolina Rojas-Córdova, Claudio Meneses-Villegas, Elizabeth Lam-Esquenazi and Angélica Flores-Bustos
Mathematics 2026, 14(10), 1734; https://doi.org/10.3390/math14101734 - 18 May 2026
Viewed by 210
Abstract
Narrative extraction algorithms construct storylines by finding coherent paths through document collections. The Narrative Trails algorithm frames this as maximum-capacity path optimization, where path quality depends on a coherence function measuring document relationships. We introduce quantum kernels as coherence functions for narrative extraction—to [...] Read more.
Narrative extraction algorithms construct storylines by finding coherent paths through document collections. The Narrative Trails algorithm frames this as maximum-capacity path optimization, where path quality depends on a coherence function measuring document relationships. We introduce quantum kernels as coherence functions for narrative extraction—to the best of our knowledge, the first systematic characterisation of quantum kernel methods for storyline extraction—and compare them against classical baselines on two corpora using a multi-seed protocol. The sweep covers 93 method evaluations (54 quantum kernels across three encoder families—RY+CNOT-ring, IQP/ZZ-feature-map, and a projected quantum kernel—and 39 classical kernels—cosine, RBF, and the cluster-aware Narrative Trails baseline). On 11,215 human navigation paths from Wikispeedia, evaluation metrics divide into two clusters that disagree with each other: alignment-based metrics (length-normalised DTW and per-step DTW similarity) favour methods that produce long alignment-rich paths, while set-overlap metrics (Jaccard and F1) favour methods that produce shorter paths with higher article overlap. On LLM-judged coherence for Cuban news storylines, evaluated under a 12-method × 5-seed × 30-endpoint-pair × 2-judge design (Claude Sonnet 4.5 and GPT-4o, both at T=0 via structured tool calling), the cluster-aware classical baseline is the top method in terms of mean overall coherence; the 5-method quantum-kernel pool and the 7-method classical-kernel pool on matched projection input show no significant differences after Holm correction. Cross-task analysis reveals that LLM coherence rank correlates with alignment-cluster Wikispeedia metrics (Spearman ρ+0.70) and anti-correlates with overlap-cluster metrics (ρ0.62). A closed-form theoretical analysis shows that the depth-1 RY+CNOT-ring kernel reduces to a classical product-of-cosines kernel order equivalent to RBF, explaining the absence of empirical separation at low depth; deeper encoders break the cancellation but exponentially concentrate kernel values, eroding inter-pair distinguishability. Our results characterise quantum coherence kernels as competitive with classical kernels on the same projected input rather than decisively superior, with the cluster-aware classical baseline retaining a modest advantage attributable to its explicit topical structure. Full article
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25 pages, 746 KB  
Article
Governance, Organizational Objectives, and Institutional Constraints in Cooperative Development: A Structural Equation Model of Cuban Production, Service, and Credit Cooperatives
by Elizabeth Guilarte-Barinaga, Alexander Sánchez-Rodríguez, Rodobaldo Martínez-Vivar, Gelmar García-Vidal and Reyner Pérez-Campdesuñer
Adm. Sci. 2026, 16(5), 218; https://doi.org/10.3390/admsci16050218 - 1 May 2026
Viewed by 1142
Abstract
Cooperatives are key organizational forms for economic and social development; however, the factors shaping their development are often examined in a fragmented manner. This study identifies the main dimensions of cooperative development and tests their interrelationships using structural equation modeling (SEM). Based on [...] Read more.
Cooperatives are key organizational forms for economic and social development; however, the factors shaping their development are often examined in a fragmented manner. This study identifies the main dimensions of cooperative development and tests their interrelationships using structural equation modeling (SEM). Based on a literature review and expert validation, a measurement instrument was developed and applied to 410 members from 82 cooperatives in Cuba between March and July 2025. The model was estimated and validated using confirmatory factor analysis (CFA) and SEM. The findings support an integrated framework in which cooperative values, cooperative principles, organizational objectives, community relations, and the institutional environment jointly explain cooperative development. All hypothesized relationships are positive and statistically significant, with organizational objectives and the institutional environment showing relatively stronger effects compared to normative and relational dimensions. The results demonstrate that cooperative development is a multidimensional and context-dependent process that cannot be explained by normative principles alone. Instead, it depends on the organization’s capacity to translate cooperative identity into strategic objectives and to operate within enabling institutional conditions. The study provides an empirically validated framework for analyzing cooperative governance and offers practical insights for strengthening organizational performance in emerging economies. Full article
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17 pages, 1757 KB  
Article
Energy and Exergy Assessment of a 250 MW Steam Boiler Under Partial Load Conditions: Comparative Analysis of Fuel Oil and Enhanced Crude Oil
by Yoalbys Retirado-Mediaceja, William Quitiaquez, Yanan Camaraza-Medina, Héctor Luis Laurencio-Alfonso, Carlos Zalazar, Hugo Javier Angulo Palma, Benigno Leyva De la cruz, M. Hernández-Wolpez and Liomnis Osorio
Symmetry 2026, 18(4), 647; https://doi.org/10.3390/sym18040647 - 12 Apr 2026
Viewed by 775
Abstract
This study presents a comprehensive thermo-energetic and exergetic assessment of a 250 MW steam boiler in a Cuban thermal power plant, operating under partial load conditions (plant: 62–66%; boiler: 58–61%). An integrated diagnostic methodology was developed and implemented in Mathcad 15 to evaluate [...] Read more.
This study presents a comprehensive thermo-energetic and exergetic assessment of a 250 MW steam boiler in a Cuban thermal power plant, operating under partial load conditions (plant: 62–66%; boiler: 58–61%). An integrated diagnostic methodology was developed and implemented in Mathcad 15 to evaluate key performance indicators, including thermal efficiency (ηtGV); exergetic efficiency (ηExGV); exergy destruction ratio (γExGV); steam generation index (IGv); and specific fuel consumption (BEsp). The methodology was applied to two fuels with contrasting thermophysical and chemical properties: fuel oil and Enhanced Crude Oil 650. The results indicate superior performance with fuel oil due to its higher heating value; however, efficiency losses were mainly attributed to operational factors such as excessive air supply (22.7–26.4%), heat transfer surface fouling, and inadequate maintenance. The analysis revealed significant deviations from design values—thermal efficiency (90.27–90.59%) and exergetic efficiency (<60%)—highlighting an untapped potential for energy savings. Quantitative estimates indicate potential annual fuel cost savings of approximately 1.2 million USD through optimized combustion and maintenance practices. The proposed framework enables accurate diagnostics of complex boiler systems and provides actionable indicators to support combustion optimization and energy efficiency strategies in conventional thermal power plants. Full article
(This article belongs to the Special Issue Symmetry and Thermal Engineering)
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28 pages, 1735 KB  
Systematic Review
A Systematic Review on Some Physical–Mechanical Properties Along with Tracheid Biometry of Pinus caribaea M. Wood
by Ana Gertrudis Trocones-Boggiano, Lidia Gurau, Glessler Vladimir Ramos-Giral and Mihaela Porojan
Appl. Sci. 2026, 16(7), 3503; https://doi.org/10.3390/app16073503 - 3 Apr 2026
Viewed by 462
Abstract
Pinus caribaea M. comprises three varieties: hondurensis, bahamensis and caribaea, the latter being crucial to the Cuban forestry industry. This systematic review evaluated some physical–mechanical properties and tracheid biometry of Pinus caribaea M. wood, with particular emphasis on var. caribaea, [...] Read more.
Pinus caribaea M. comprises three varieties: hondurensis, bahamensis and caribaea, the latter being crucial to the Cuban forestry industry. This systematic review evaluated some physical–mechanical properties and tracheid biometry of Pinus caribaea M. wood, with particular emphasis on var. caribaea, to identify potential knowledge gaps and followed the PRISMA 2020 guidelines. The investigation was conducted in four databases, including gray literature up to December 2024, and the risk of bias was assessed using a tool adapted from the JBI critical appraisal checklist. A total of 535 studies were identified, of which 75 were included in the review based on the inclusion criteria. It was found that only 17.3% of the selected publications focus on var. caribaea. Most studies evaluate physical properties, with less attention paid to mechanical properties and cell biometry. A downward trend in recent publications was noted for this variety, along with a predominance of the radial direction as a source of variation. A lack of research on mature trees (>30 years) as well as other sources of variation were identified as information gaps. Value ranges for density, shrinkage, modulus of elasticity and modulus of rupture in static bending, compressive strength parallel to the grain, as well as tracheid biometry were synthesized from the available publications for all varieties. It is concluded that var. caribaea is under-researched, and a systematic study is therefore required to optimize its use and industrial impact. Full article
(This article belongs to the Section Materials Science and Engineering)
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13 pages, 368 KB  
Article
Competitive Anxiety as a Predictor of the Occurrence, Quantity, and Severity of Injuries in Young Cuban Athletes
by Jesús Ríos-Garit, Yanet Pérez-Surita, Verónica Gómez-Espejo, Mario Reyes-Bossio and Verónica Tutte-Vallarino
Int. J. Environ. Res. Public Health 2026, 23(3), 354; https://doi.org/10.3390/ijerph23030354 - 11 Mar 2026
Viewed by 596
Abstract
Previous studies suggest that elevated competitive anxiety may increase the likelihood of injury. The present research aims to examine the role of competitive anxiety as a predictor of injury occurrence, frequency, and severity. A cross-sectional, correlational design was conducted with 131 athletes (mean [...] Read more.
Previous studies suggest that elevated competitive anxiety may increase the likelihood of injury. The present research aims to examine the role of competitive anxiety as a predictor of injury occurrence, frequency, and severity. A cross-sectional, correlational design was conducted with 131 athletes (mean age = 16.49 years), predominantly male. Injury data were obtained through medical record review, and competitive anxiety was assessed using the Competitive Anxiety Inventory-2. Empirical frequency distributions, descriptive statistics, non-parametric tests, and logistic and ordinal regression models were employed. A high incidence of injuries was observed, although most were minor. Competitive anxiety was characterized by elevated levels of cognitive anxiety and self-confidence. Injured athletes exhibited greater overall competitive anxiety (r = 0.31, p < 0.001), with higher levels observed among those who sustained more injuries (ε2 = 0.12, p = 0.001), and a very large effect was found in relation to injury severity (ε2 = 0.17, p < 0.001). The occurrence of injury can only be predicted in 10.9–14.7% of cases through increased cognitive and somatic anxiety, whereas an increase across all dimensions of competitive anxiety predicts a greater number (13–14%) and severity (20.3–21.8%) of injuries. These findings underscore the importance of developing skills to manage competitive anxiety, particularly its cognitive dimension and maintaining optimal levels of self-confidence in young athletes. Full article
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11 pages, 988 KB  
Article
Vibrational Spectroscopy and Computational Studies of Cubane-1,4-Dicarboxylic Acid
by Stewart F. Parker, James P. Tellam and Sarah E. Youngs
Molecules 2026, 31(4), 592; https://doi.org/10.3390/molecules31040592 - 9 Feb 2026
Viewed by 528
Abstract
Cubane-1,4-dicarboxylic acid is a key intermediate in the synthesis of the Platonic solid, cubane. While cubane has been extensively studied, its precursor has not. Here, we provide a comprehensive characterization of the vibrational spectra (infrared, Raman, inelastic neutron scattering (INS)) of cubane-1,4-dicarboxylic acid [...] Read more.
Cubane-1,4-dicarboxylic acid is a key intermediate in the synthesis of the Platonic solid, cubane. While cubane has been extensively studied, its precursor has not. Here, we provide a comprehensive characterization of the vibrational spectra (infrared, Raman, inelastic neutron scattering (INS)) of cubane-1,4-dicarboxylic acid and its isotopomer with the acidic hydrogens exchanged for deuterium. In combination with density functional theory studies of the complete unit cell, we show that the dynamics of the carboxylic acid and the cubane core are largely independent; the effect is mostly the result of the increased mass of the substituent at the 1,4 positions: 45 versus 1. The known crystal structure is unusual in that the carboxylic acid is present as two conformers: syn and anti. The calculations show that the in-plane and out-of-plane C–O–H bending modes have different transition energies in the two conformers. For all the other modes, both conformers contribute approximately equally. Full article
(This article belongs to the Section Physical Chemistry)
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26 pages, 5501 KB  
Review
Ligand-Induced Self-Assembly of Clusters by Pyridine–Amine–Carboxylate Frameworks of 3D Transition Metals: Structural and Magnetic Aspects
by Amit Rajput, Akram Ali, Himanshu Arora and Akhilesh Kumar
Magnetochemistry 2026, 12(2), 22; https://doi.org/10.3390/magnetochemistry12020022 - 4 Feb 2026
Viewed by 2044
Abstract
The ligand-driven self-assembly of metal clusters offers a powerful strategy for constructing discrete molecular architectures with tunable magnetic and structural properties. By judiciously selecting appropriate multidentate ligands, researchers can direct the formation of polynuclear metal assemblies with diverse nuclearities, geometries, and topologies. Coordination-driven [...] Read more.
The ligand-driven self-assembly of metal clusters offers a powerful strategy for constructing discrete molecular architectures with tunable magnetic and structural properties. By judiciously selecting appropriate multidentate ligands, researchers can direct the formation of polynuclear metal assemblies with diverse nuclearities, geometries, and topologies. Coordination-driven processes commonly stabilize such assemblies where multidentate ligands operate as templates and linkers. These will also determine how the metal centers are arranged in space and how they connect to each other. These clusters can take on shapes that range from basic bridging dimers to more complicated icosahedral and cubane-type motifs. They often have excellent symmetry and strong frameworks. Magnetically, these clusters are a great place to study exchange interactions, spin frustration, and the behavior of single-molecule magnets (SMMs). The magnetic characteristics depend on things like the type of metal ions, the bridging ligands, the overall shape, and the local coordination environment. Interestingly, a large number of ligand-assembled clusters exhibit high spin ground states and slow magnetization relaxation, which makes them attractive options for quantum information storage and molecular spintronic devices. This review connects coordination chemistry, supramolecular design, and molecular magnetism of pyridine–amine–carboxylate frameworks, offering insights into fundamental magnetic phenomena and guiding the development of next-generation functional materials. Continued exploration of ligand frameworks and metal combinations holds the potential to yield novel clusters with enhanced or unprecedented magnetic characteristics. Full article
(This article belongs to the Special Issue Stimuli-Responsive Magnetic Molecular Materials—2nd Edition)
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6 pages, 735 KB  
Article
Viruses Infecting Cuban Honey Bees and Evolution of Deformed-Wing-Virus Variants
by Poppy J. Hesketh-Best, Anais R. Luis, Declan C. Schroeder and Stephen J. Martin
Viruses 2026, 18(1), 148; https://doi.org/10.3390/v18010148 - 22 Jan 2026
Cited by 1 | Viewed by 881
Abstract
Cuba is in a unique situation in which it has a large (220,000 managed colonies) and isolated honey bee population due to a 60+ year ban on the importation of bees. Despite this, the ectoparasitic mite Varroa destructor arrived in 1996, and with [...] Read more.
Cuba is in a unique situation in which it has a large (220,000 managed colonies) and isolated honey bee population due to a 60+ year ban on the importation of bees. Despite this, the ectoparasitic mite Varroa destructor arrived in 1996, and with it came deformed wing virus (DWV). In 2018, an island-wide survey detected varroa and DWV in 91% of colonies. In this study, we conducted a full-virome analysis on some of these samples, along with additional samples collected in 2021. For the first time, we detected two variants of Lake Sinai Virus and confirmed the absence of the normally widespread black queen cell virus in Cuba. We also detected both DWV-A and DWV-B master variants, with DWV-B being the dominant variant. Interestingly, the DWV-B/A recombinant was also detected, indicating that despite Cuba’s isolated nature, the pattern of DWV evolution mirrors that found in the USA and Europe. However, this pattern is not found in neighboring Latin America, China, or Japan, where the DWV-A master variant continues to be dominant. How and why two distinct evolutionary DWV pathways have arisen remain a mystery. Full article
(This article belongs to the Special Issue Advances in Honey Bee Viruses Research)
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13 pages, 2630 KB  
Article
Rectal Colonization by Carbapenemase-Producing Enterobacterales in a Tertiary Care Hospital in Havana, Cuba
by Haiyang Yu, Yenisel Carmona, Vismayda Bouza, María Karla González, Gonzalo Estevez Torres, Valia Ramos Rodríguez, Alberto Hernández González, Nobumichi Kobayashi, Meiji Soe Aung, Patricia Ruiz-Garbajosa, Rafael Cantón and Dianelys Quiñones Pérez
Antibiotics 2026, 15(1), 109; https://doi.org/10.3390/antibiotics15010109 - 22 Jan 2026
Viewed by 1020
Abstract
Introduction: Rectal colonization by carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) is a risk factor for subsequent infections, which are associated with high mortality rates. Methods: A cross-sectional study was conducted. Rectal swabs were collected from 297 patients within 48 h of admission to eight high-prevalence [...] Read more.
Introduction: Rectal colonization by carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) is a risk factor for subsequent infections, which are associated with high mortality rates. Methods: A cross-sectional study was conducted. Rectal swabs were collected from 297 patients within 48 h of admission to eight high-prevalence CP-CRE hospital departments, with follow-up swabs taken weekly for up to 4 weeks. Species identification, antimicrobial susceptibility testing, and genetic detection of carbapenemases were performed. The genetic relationship among isolates was assessed using ERIC-PCR, combined with epidemiological data, to investigate subsequent infections. Results: Fecal carriage of CP-CRE was detected in 15.5% (46/297) of patients- All carbapenemases were metallo-betalactamases, with dominance of NDM-producing Klebsiella pneumoniae. NDM + VIM-producing Escherichia coli were also detected. Among carriers, 26.1% were colonized by two different CRE species, and 86.9% had a history of prior hospitalization. Molecular analysis revealed clonal expansion, suggesting outbreaks among colonized patients. Additionally, 17.4% (8/46) of colonized patients developed an infection, which was significantly associated with urinary catheter use (p = 0.040), mechanical ventilation (p = 0.044), and surgical procedures (p = 0.040). Conclusions: rectal colonization by CP-CRE in hospitalized patients is a serious epidemiological concern, with evidence of clonal spread and subsequent infection in colonized patients. NDM-producing K. pneumoniae was also predominant, detecting co-production of NDM + VIM in E. coli. These findings underscore the urgent need to implement epidemiological surveillance cultures to improve the prevention and control of CP-CRE infections in Cuban hospitals. Full article
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17 pages, 3103 KB  
Article
Multi-Analytical Insight into the Non-Volatile Phytochemical Composition of Coleus aromaticus (Roxb.) Benth.
by Chiara Toniolo, Martina Bortolami, Adriano Patriarca, Daniela De Vita, Fabio Sciubba and Luca Santi
Metabolites 2026, 16(1), 15; https://doi.org/10.3390/metabo16010015 - 23 Dec 2025
Viewed by 729
Abstract
Background/Objectives: Coleus aromaticus (Lamiaceae), also known as Cuban oregano or Indian borage, is a semi-succulent perennial species widely used in traditional medicine for its therapeutic and nutritional properties. While its essential oils and aromatic fraction have been extensively investigated, the characterization of [...] Read more.
Background/Objectives: Coleus aromaticus (Lamiaceae), also known as Cuban oregano or Indian borage, is a semi-succulent perennial species widely used in traditional medicine for its therapeutic and nutritional properties. While its essential oils and aromatic fraction have been extensively investigated, the characterization of its non-volatile metabolites remains limited. The aim of this study was to explore the chemical composition of fresh leaves with a focus on the non-volatile fraction. Methods: Fresh leaves of C. aromaticus were cryogenically treated with liquid nitrogen, ground, and subjected to three different extraction procedures: hydroalcoholic maceration, ethyl acetate maceration, and liquid–liquid partitioning to obtain a dichloromethane organic phase and a hydroalcoholic phase. Extracts and fractions were analyzed by HPTLC and HPLC for metabolic profiling. In addition, the Bligh–Dyer method was applied to separate polar and non-polar metabolites, which were subsequently characterized using NMR spectroscopy. Results: Chromatographic analyses highlighted the occurrence and distribution of organic acids, polyphenols (notably flavonoids), and proteinogenic amino acids. Spectroscopic data confirmed the presence of diverse polar and non-polar metabolites, providing a more detailed chemical fingerprint of C. aromaticus. This integrated approach broadened the phytochemical profile of the species beyond the well-documented essential oils. Conclusions: The results contribute to a better understanding of the non-volatile metabolites of C. aromaticus, offering novel insights into its chemical diversity. These findings highlight the potential of this plant as a valuable source of bioactive compounds, supporting its future application in nutraceutical and pharmaceutical research. Full article
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