Search Results (196)

Evaluating the coherence of narrative sequences extracted from large document collections is crucial for applications in information retrieval and knowledge discovery. While mathematical coherence metrics based on embedding similarities provide objective measures, they require substantial computational resources and domain expertise to interpret. We propose using large language models (LLMs) as judges to evaluate narrative coherence, demonstrating that their assessments correlate with mathematical coherence metrics. Through experiments on two data sets—news articles about Cuban protests and scientific papers from visualization conferences—we show that the LLM judges achieve Pearson correlations up to 0.65 with mathematical coherence while maintaining high inter-rater reliability (ICC > 0.92). The simplest evaluation approach achieves a comparable performance to the more complex approaches, even outperforming them for focused data sets while achieving over 90% of their performance for the more diverse data sets while using less computational resources. Our findings indicate that LLM-as-a-judge approaches are effective as a proxy for mathematical coherence in the context of narrative extraction evaluation. Full article

President John F Kennedy faced an impending crisis upon taking office in January 1961. The revolutionary threat of Cuba held the potential to spread to several neighboring countries. This crisis was the product of decades of neglect from successive US presidents, that ultimately invited the USSR into the region and fell to Kennedy during his first year as President. Kennedy sought to recast the image of the US in the hemisphere to inoculate against the example of Cuba. The cornerstone of this plan was the Alliance for Progress, a substantial program of economic assistance from the US to Latin America. However, that program has widely been criticized as a failure. Rather than reflect on the economic and social limitations of the Alliance for Progress, this paper will evaluate the diplomatic impact of Kennedy’s approach in forming the anti-Cuban coalition in the first year of his presidency. Kennedy successfully changed the Latin American attitude towards the US prior to the releasing of any substantial economic aid. Therefore, this paper will argue that “The Kennedy Plan” was a diplomatic success that reduced the threat of Castro’s Cuba in the context of the Cold War. Full article

In Cuba, coastal zone management is a matter of environmental priority. The Cuban State has legislated its protection mechanisms, actions, and instruments according to a high-hierarchical-rank legal norm. This article revealed the institutional frameworks and implementation strategies that support the socio-ecosystemic approach in coastal marine governance in the southeastern region of Santiago de Cuba, focusing on the management practices of integrated coastal zone management (ICZM) programs. Under the logic of ICZM principles, a scientometric, exegetical–legal study was carried out, with thematic content analysis, using the Driving Forces–Pressures–State–Impacts–Respond (DPSIR) framework. The methodology to meet the objectives was based on three analytical stages that generated scientific proposals for implementing the socio-ecosystemic approach in adaptive coastal governance practices. As a result, it is demonstrated that this approach has a scientific and legal proposal in Cuba, and its dynamics in coastal management programs are revealed. This study indicates that the logic of the DPSIR framework provides a propositional platform that helps structure the fundamentals of the proposed approach with reference to objectives and responses of coastal marine governance in Cuba. Full article

Purpose: This case study examines the anthropometric characteristics and body composition changes of a 41-year-old Cuban Greco-Roman 130 kg wrestler, a five-time Olympic gold medalist (2008–2024). To optimize his preparation for the Paris 2024 Olympic Games, another athlete participated in the qualifying process, allowing him to train without competition gear. Methods: The study monitored changes in body composition using anthropometry and bioelectrical impedance analysis (BIA) at three key time points in 2024: January, June, and July. The final assessment occurred 25 days before the Olympic event, coinciding with the final phase of his preparation. Results: The analysis revealed a significant reduction in total body mass, from 150 kg in January to 138.5 kg in July, with fat mass decreasing from 37.06 kg (24.11%) to 29.7 kg (21.5%). Muscle mass decreased slightly (77.41 kg to 72.3 kg), while bone mass remained stable. The somatotype classification was endomorphic–mesomorphic at all assessments, with slight shifts in its components (4.6–10.4–0.1 in January to 4.4–10.3–0.1 in July), reflecting an improved muscle–fat ratio. Notably, hydration levels and cellular integrity remained stable, as indicated by BIVA analysis. Conclusions: This study provides insight into the anthropometric characteristics and body composition of an elite Greco-Roman wrestler, as well as the changes observed during his preparation for his final Olympic participation. These data serve as a valuable reference for wrestlers and sports professionals, highlighting the physical profile of one of the most emblematic figures in Olympic history. Full article

The efficacy of Cuban sugarcane-extracted policosanol (Raydel^®), a purified blend of eight long-chain aliphatic alcohols, was compared to copycat sugarcane-extract powder (SCEP) to assess their effects on dyslipidemia, oxidative stress, and vital organs of zebrafish under the influence of a high-cholesterol diet (HCD). Zebrafish were fed with HCD (final 4%, w/w) or HCD infused with policosanol (PCO, final 1%, w/w) or SCEP (final 1%, w/w). Post 14-week consumption, blood and organs were harvested and processed for various biochemical, histological, and immunohistochemical (IHC) examinations, and fluorescent staining. Following 14-week consumption, the PCO-supplemented group exhibited higher zebrafish survival probability than the SCEP-supplemented group. Both PCO and SCEP substantially impacted the HCD-disrupted plasma lipid profile; however, PCO supplementation exhibited a significantly better effect than SCEP. Similarly, PCO supplementation significantly improved the blood glucose level, hepatic function biomarkers, and oxidative-antioxidant balance disturbed by HCD. PCO supplementation displayed a substantial inhibitory effect against HCD-induced fatty liver changes, nephromegaly, and cellular senescence. Likewise, PCO effectively protected the brain against HCD-induced apoptosis and accumulation of 4-hydroxynonenal (4-HNE); in contrast, SCEP supplementation showed almost no effect in reducing such adverse changes. The comparative findings between PCO and SCEP highlight the protective effects of PCO against HCD-induced oxidative stress and dyslipidemia via the enhancement of antioxidant markers, leading to protection of the liver, kidney, and brain, while SCEP failed to achieve similar outcomes. Full article

Background: Racotumomab-alum is an anti-idiotype vaccine targeting the NeuGcGM3 tumor-associated ganglioside. Clinical trials in advanced cancer patients have demonstrated low toxicity, high immunogenicity and clinical benefit. The goal of this study was to identify circulating biomarkers of clinical outcome. Methods: Eighteen patients with stage IIIb/IV non-small-cell lung cancer (NSCLC) were injected with racotumomab-alum as switch maintenance therapy after first-line chemotherapy. Treatment was administered until severe performance status worsening or toxicity. The frequencies of innate and adaptive lymphocytes were assessed by flow cytometry. Circulating factors were measured using multi-analyte flow assay kits. Results: The median overall survival was 16.5 months. Twenty-seven percent of patients were classified as long-term survivors. Patients with lower baseline frequencies of CD4+Tregs and central memory (CM) CD8+T cells displayed longer survival rates. Furthermore, higher baseline frequencies of NKT cells and a high CD8+T/CD4+Treg ratio were associated with longer survival. Interestingly, patients with significantly lower levels of effector memory (EM) CD8+T cells survived longer. The levels of NKT cells and terminal effector memory (EMRA) CD8+T cells were higher in long-term survivors in comparison with short-term survivors in post-immune samples. As expected, the ratio of CD8+T/CD4+Tregs showed significantly higher values during treatment in patients with clinical benefits. Regarding serum factors, pro-tumorigenic cytokines significantly increased during treatment in poor survivors. Conclusions: In advanced NSCLC patients receiving racotumomab-alum vaccine, longer survival could be associated with a unique profile of circulating lymphocyte subsets at baseline and during treatment. Additionally, certain pro-tumor-related cytokines increased in short-term survivors. These results should be confirmed in larger randomized clinical trials. This clinical trial was registered in the Cuban Clinical Trials Register (RPCE00000279). Full article

Two tetranuclear complexes were obtained by a self-assembly process employing di-2-pyridyl ketone ((py)₂CO), benzoate and M(NO₃)₂ (M = Co and Ni). The compounds [M₄{(py)₂C(OH)O}₄(O₂CPh)₄], where {(py)₂C(OH)O}⁻ is the monoanion of the gem-diol form of (py)₂CO, were characterized through single-crystal X-ray diffraction and magnetic measurements. Structural analysis revealed that both complexes possess a [M₄O₄] cubane-like core. A two-J model and magnetic anisotropy were employed to analyze the magnetic properties of both compounds. These studies indicate the presence of dominant ferromagnetic interactions within both tetranuclear cores. DFT and CASSCF/NEVPT2 calculations were also performed to support the fitting of experimental magnetic data. Full article

For the Cuban littorals in the Caribbean Sea, information on benthic diatoms is scarce, and hitherto non-existent for natural protected areas. Thus, to describe the structure of benthic diatom associations (BDAs) from a marine protected area in Cuba, sediment samples were collected in Playa Las Gaviotas (Refugio de Vida Silvestre Cayo Santa María) during dry (November) and rainy (July) seasons. Diatoms were separated, mounted in synthetic resin and identified under light microscopy. Species diversity of the BDA was estimated using Shannon (H′), Simpson (1 − λ) and Pielou evenness (J′) indices. We identified 354 taxa including 200 new records for Cuba; the nomenclature of 45 previously recorded taxa was updated. The currently recorded species richness of marine benthic diatoms for Cuba is 595. The most abundant taxa were Amphora cf. copulata, A. proteus, Diploneis smith var. pumila, Halamphora turgida, H. coffeiformis, Navicula zostereti, Nitzschia marginulata var. didyma and Psammodictyon panduriforme. The best-represented genus was Mastogloia with 70 taxa. Similarity values indicated homogeneous distribution of epipelic diatom taxa along the sandy bottom, suggesting a single diatom association. Mean values of H′ ranged from 4.91 bit/taxon in November to 4.95 bit/taxon in July. Structure analysis suggests a stable BDA with high species diversity characteristic of productive, pristine environments. Full article

Background: A comparative 12-week dietary intervention of red yeast rice (RYR, Beni-koji, Kobayashi, Japan) and Cuban policosanol (PCO, Raydel^®, Thornleigh, Australia) was assessed for dyslipidemia, antioxidant status, and vital organ functionality in hyperlipidemic zebrafish. Methods: Hyperlipidemic zebrafish were supplemented with a high-cholesterol diet (HC, final 4%, w/w) infused with either a powdered RYR tablet (final 1.0%, w/w), a PCO tablet (final 1.0%, w/w), or a combination of 0.5% (w/w) each of RYR and PCO powder for 12 weeks. Subsequently, blood and organs were collected and processed for biochemical and histological examination. Results: RYR and PCO consumption showed a substantial effect against HC-induced hyperlipidemia by reducing the total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C). Exclusively, PCO supplementation revealed a significant elevation in the HC-diminished high-density lipoprotein cholesterol (HDL-C). In addition, PCO supplementation showed a significant elevation in plasma ferric ion-reducing ability (FRA) and sulfhydryl content, as well as alleviating the blood glucose level of hyperlipidemic zebrafish. The most noteworthy impact, with a significant two-fold (p < 0.001) augmentation of HC-diminished plasma paraoxonase (PON) activity, was observed in response to PCO. In contrast, the RYR supplementation failed to establish curative effects against HC-disturbed plasma antioxidant variables and blood glucose levels. The histological outcome revealed a severe toxicological impact of the RYR on the liver, reflected by fatty liver changes and three-fold heightened IL-6 production compared to HC control. Contrastingly, PCO exhibited significant hepatoprotection and effectively neutralized the hepatic toxicity triggered by HC and RYR. Also, RYR showed kidney atrophy, intense ROS generation, apoptosis, and senescence. Conversely, the PCO supplementation protected the kidney from HC- and RYR-induced toxicity. Likewise, PCO supplementation notably alleviated histological alterations and oxidative stress in the brain, ovary, and testis of hyperlipidemic zebrafish. Conclusions: This comparative study establishes PCO’s therapeutic effect against the challenges posed by HC, while RYR emerged with serious toxicological concerns towards the liver, kidney, and other organs of hyperlipidemic zebrafish. Full article

Secondhand smoke affects nearly 40% of children worldwide, leading to serious health and behavioral problems. Being neurotoxic, it poses potential risks for child health and learning. In Cuba, there is limited research on the association of secondhand smoke with children’s brain health, especially in vulnerable populations like young children at home. The overall purpose of this study is two-fold. First, we determined the relationship between household smoke exposure and risks to brain health in Cuban children. Second, we analyzed the role of family environment factors, such as socio-economic status, in our estimates. Although this research represents the first investigation of its kind in Cuba, we expect to find evidence of neurotoxic associations with household smoke. We collected data between 2015 and 2018 using the medical records of 627 Cuban preschool children to explore the link between brain health indicators and exposure to tobacco smoke at home. We assessed archival reports on parental smoking, duration and frequency of exposure, and several indicators of brain health, including executive function, language development, sleep quality, and fluid intelligence. The findings indicate that exposure to tobacco smoke at home has a negative association with children’s brain health, affecting both the cognitive (executive and linguistic functions) and non-cognitive aspects (sleep quality) of child development. Continuous exposure (five to seven times per week) and transient exposure (two to three times per week) were found to be more negatively related to sleep quality than in cognitive functions, particularly in children of middle socio-economic status. This highlights the need to implement parental information campaigns in Cuba. Full article

This study focuses on the relationship between hotel sites (current and planned) and exposure to hurricanes in Cuba. The hypothesis focused on demonstrating that Cuban tourist areas have differing degrees of exposure to tropical cyclones according to the month. The results indicate that although the whole Cuban archipelago is exposed to hurricanes, the tourist regions in Cuba’s western provinces have a greater chance of being affected than those located in the center, east, and south. The tourism development that will take place by 2030 in Cuba includes significant hotel expansion in coastal areas that are highly exposed to hurricanes. Information on the risk of hurricanes in tourist regions provides information that could enable the creation of the organizational conditions needed to tackle these phenomena in the short to medium term and to refine spatial and tourism planning approaches in the long term. Full article

Although urbanization is a major threat to biodiversity, some native species have managed to persist in urban areas. Populations of such species often show phenotypic differences with their rural counterparts. A crucial question is whether such differences result from different selection regimes between habitats. As previous studies showed that suburban and forest populations of Anolis homolechis differ in both body size and sex ratio, we tested the effect of urbanization on adult survival in those populations based on a long-term capture–marking–recapture survey and replicated design. We assessed the evidence for directional and stabilizing selection on size in two suburban and two forest populations by modeling apparent adult survival and recapture probability separately. Adult survival did not differ between habitat types. In addition, there was no evidence for size-related differential selection on adult survival between habitats. However, irrespective of habitat, we found significant stabilizing selection on female size, whereas male survival was independent of size. Overall, sex had a significant effect on survival independent of habitat type (monthly survival probability: 0.80 for males vs. up to 0.89 for females of optimal size). We discuss our results in relation to the potential mechanisms involved in the observed phenotypic differentiation of A. homolechis and other lizard species in areas transformed by urbanization. Full article

During a floristic inspection of sediment samples from Playa Las Gaviotas, 69 specific and infra-specific taxa of Mastogloia were identified in the diatom taxocenosis, including 42 unrecorded taxa for the Cuban coasts. These are added to the 59 Mastogloia taxa previously listed. In this way, currently, the 101 Mastogloia comprised in the benthic diatom associations of the Cuban coast constitute the highest number of taxa ever recorded in similar floristic studies, which also indicates their tropical affinity. Furthermore, observations are made on misidentified taxa such as Mastogloia (Orthoneis) aspera, M. asperuloides, M. (Orthoneis) clevei, M. floridensis, M. latecostata, M. laterorostrata, M. ovata, M. sigillata, M. pseudolatecostata, and others. Full article

Plants belonging to the genus Maytenus are members of the Celastraceae family. They have been widely used by different peoples as treatment for curing many diseases. The aim of this study was to explore the anti-inflammatory and antioxidant properties of Maytenus elaeodendroides stem bark extracts, an endemic Cuban plant. The antioxidant activity of four extracts (EtOH, EtOAc, n-BuOH, and diethyl ether/petroleum ether 1:1) was determined using DPPH and FRAP methods. Meanwhile, anti-inflammatory effects by the edema method were induced by croton oil in the mouse ear. The investigated extracts showed radical reduction capacity and prevented ear inflammation at doses of 4 mg/ear. In addition, FIA/ESI/IT/MSⁿ was used to determine the qualitative chemical composition of the EtOAc extract and allowed the identification of five flavan-3-ol monomers, four dimers, and other proanthocyanidin oligomers. From this extract three flavan-3-ol compounds (elaeocyanidin and 4′-O-methylgallocatechin), one of them new (2′-hydroxy-4′-methoxy-epigallocatechin), and a proanthocyanidin dimer (afzelechin-($4\mathsf{\beta }\text{→}8$)-4′-O-methylepigallocatechin) were isolated and identified by the chromatographic method and spectroscopic techniques, mainly ESI-MS and NMR spectroscopic methods. Full article

This article explores the emergence and development of Neo-santeria in Barcelona, a contemporary trend of Afro-Cuban religious practices characterized by the rejection of animal sacrifice, a central ritual in traditional Santeria. The study identifies and analyzes four key arguments employed by Neo-santeros to legitimize this rejection within the secular and modern European context: the scientistic, de-traditionalist, individualistic, and ecologist arguments. Drawing on over a decade of ethnographic research, the article demonstrates how Neo-santeros navigate the tension between distancing themselves from certain traditional spiritual roots—particularly the practice of animal sacrifice—and the intertwining with European and contemporary cultural logics, particularly those related to secularism. The article situates Neo-santeria within the broader landscape of European holistic spiritualities, highlighting its strategic positioning as a religion that aligns with and challenges secularist expectations in modern Europe. The findings contribute to a deeper understanding of how Afro-Cuban religions, particularly Neo-Santería, can be defined by the ongoing creativity of their practitioners. This distinctive feature not only defines the fluid nature of these traditions but also contributes to the diversification and increased complexity of the spiritual landscape in European contexts, where Afro-Cuban practices are being intertwined in local cultural and religious frameworks. Full article