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3 Results Found

  • Article
  • Open Access
14 Citations
6,297 Views
15 Pages

Acetic Acid as Processing Aid Dramatically Improves Organic Solvent Solubility of Weakly Basic Drugs for Spray Dried Dispersion Manufacture

  • Molly S. Adam,
  • Warren K. Miller,
  • Amanda M. Pluntze,
  • Aaron M. Stewart and ,
  • Jonathan L. Cape,
  • Michael E. Grass and
  • Michael M. Morgen
  • + 2 authors+ 0 author

Many active pharmaceutical ingredients (APIs) in the pharmaceutical pipeline require bioavailability enhancing formulations due to very low aqueous solubility. Although spray dried dispersions (SDDs) have demonstrated broad utility in enhancing the b...

(This article belongs to the Special Issue Recent Progress in Formulation Approaches for Improving the Solubility and Bioavailability of Poorly Soluble Drugs)
  • Article
  • Open Access
10 Citations
3,834 Views
20 Pages

25 February 2021

Roads with low traffic volume link rural settlements together and connect them with urban centres, mobilising goods and agricultural products, and facilitating the transportation of people. In Colombia, most of these roads are in poor conditions, cau...

(This article belongs to the Special Issue Sustainable Pavement Engineering and Road Materials)
  • Review
  • Open Access
41 Citations
6,501 Views
28 Pages

Flavonoids in the Spotlight: Bridging the Gap between Physicochemical Properties and Formulation Strategies

  • Marta Berga,
  • Konstantins Logviss,
  • Liga Lauberte,
  • Artūrs Paulausks and
  • Valentyn Mohylyuk

3 October 2023

Flavonoids are hydroxylated polyphenols that are widely distributed in plants with diverse health benefits. Despite their popularity, the bioavailability of flavonoids is often overlooked, impacting their efficacy and the comparison of products. The...

(This article belongs to the Section Natural Products)