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Keywords = biomedical data gateway

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21 pages, 2794 KB  
Article
Medical Data over Sound—CardiaWhisper Concept
by Radovan Stojanović, Jovan Đurković, Mihailo Vukmirović, Blagoje Babić, Vesna Miranović and Andrej Škraba
Sensors 2025, 25(15), 4573; https://doi.org/10.3390/s25154573 - 24 Jul 2025
Viewed by 3011
Abstract
Data over sound (DoS) is an established technique that has experienced a resurgence in recent years, finding applications in areas such as contactless payments, device pairing, authentication, presence detection, toys, and offline data transfer. This study introduces CardiaWhisper, a system that extends the [...] Read more.
Data over sound (DoS) is an established technique that has experienced a resurgence in recent years, finding applications in areas such as contactless payments, device pairing, authentication, presence detection, toys, and offline data transfer. This study introduces CardiaWhisper, a system that extends the DoS concept to the medical domain by using a medical data-over-sound (MDoS) framework. CardiaWhisper integrates wearable biomedical sensors with home care systems, edge or IoT gateways, and telemedical networks or cloud platforms. Using a transmitter device, vital signs such as ECG (electrocardiogram) signals, PPG (photoplethysmogram) signals, RR (respiratory rate), and ACC (acceleration/movement) are sensed, conditioned, encoded, and acoustically transmitted to a nearby receiver—typically a smartphone, tablet, or other gadget—and can be further relayed to edge and cloud infrastructures. As a case study, this paper presents the real-time transmission and processing of ECG signals. The transmitter integrates an ECG sensing module, an encoder (either a PLL-based FM modulator chip or a microcontroller), and a sound emitter in the form of a standard piezoelectric speaker. The receiver, in the form of a mobile phone, tablet, or desktop computer, captures the acoustic signal via its built-in microphone and executes software routines to decode the data. It then enables a range of control and visualization functions for both local and remote users. Emphasis is placed on describing the system architecture and its key components, as well as the software methodologies used for signal decoding on the receiver side, where several algorithms are implemented using open-source, platform-independent technologies, such as JavaScript, HTML, and CSS. While the main focus is on the transmission of analog data, digital data transmission is also illustrated. The CardiaWhisper system is evaluated across several performance parameters, including functionality, complexity, speed, noise immunity, power consumption, range, and cost-efficiency. Quantitative measurements of the signal-to-noise ratio (SNR) were performed in various realistic indoor scenarios, including different distances, obstacles, and noise environments. Preliminary results are presented, along with a discussion of design challenges, limitations, and feasible applications. Our experience demonstrates that CardiaWhisper provides a low-power, eco-friendly alternative to traditional RF or Bluetooth-based medical wearables in various applications. Full article
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22 pages, 2918 KB  
Article
Design and Development of a Low-Power IoT System for Continuous Temperature Monitoring
by Luis Miguel Pires, João Figueiredo, Ricardo Martins, João Nascimento and José Martins
Designs 2025, 9(3), 73; https://doi.org/10.3390/designs9030073 - 12 Jun 2025
Cited by 1 | Viewed by 3284
Abstract
This article presents the development of a compact, high-precision, and energy-efficient temperature monitoring system designed for tracking applications where continuous and accurate thermal monitoring is essential. Built around the HY0020 System-on-Chip (SoC), the system integrates two bandgap-based temperature sensors—one internal to the SoC [...] Read more.
This article presents the development of a compact, high-precision, and energy-efficient temperature monitoring system designed for tracking applications where continuous and accurate thermal monitoring is essential. Built around the HY0020 System-on-Chip (SoC), the system integrates two bandgap-based temperature sensors—one internal to the SoC and one external (Si7020-A20)—mounted on a custom PCB and powered by a coin cell battery. A distinctive feature of the system is its support for real-time parameterization of the internal sensor, which enables advanced capabilities such as thermal profiling, cross-validation, and onboard diagnostics. The system was evaluated under both room temperature and refrigeration conditions, demonstrating high accuracy with the internal sensor showing an average error of 0.041 °C and −0.36 °C, respectively, and absolute errors below ±0.5 °C. With an average current draw of just 0.01727 mA, the system achieves an estimated autonomy of 6.6 years on a 1000 mAh battery. Data are transmitted via Bluetooth Low Energy (BLE) to a Raspberry Pi 4 gateway and forwarded to an IoT cloud platform for remote access and analysis. With a total cost of approximately EUR 20 and built entirely from commercially available components, this system offers a scalable and cost-effective solution for a wide range of temperature-sensitive applications. Its combination of precision, long-term autonomy, and advanced diagnostic capabilities make it suitable for deployment in diverse fields such as supply chain monitoring, environmental sensing, biomedical storage, and smart infrastructure—where reliable, low-maintenance thermal tracking is essential. Full article
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17 pages, 1278 KB  
Review
Innovations in Genomics and Big Data Analytics for Personalized Medicine and Health Care: A Review
by Mubashir Hassan, Faryal Mehwish Awan, Anam Naz, Enrique J. deAndrés-Galiana, Oscar Alvarez, Ana Cernea, Lucas Fernández-Brillet, Juan Luis Fernández-Martínez and Andrzej Kloczkowski
Int. J. Mol. Sci. 2022, 23(9), 4645; https://doi.org/10.3390/ijms23094645 - 22 Apr 2022
Cited by 199 | Viewed by 25320
Abstract
Big data in health care is a fast-growing field and a new paradigm that is transforming case-based studies to large-scale, data-driven research. As big data is dependent on the advancement of new data standards, technology, and relevant research, the future development of big [...] Read more.
Big data in health care is a fast-growing field and a new paradigm that is transforming case-based studies to large-scale, data-driven research. As big data is dependent on the advancement of new data standards, technology, and relevant research, the future development of big data applications holds foreseeable promise in the modern day health care revolution. Enormously large, rapidly growing collections of biomedical omics-data (genomics, proteomics, transcriptomics, metabolomics, glycomics, etc.) and clinical data create major challenges and opportunities for their analysis and interpretation and open new computational gateways to address these issues. The design of new robust algorithms that are most suitable to properly analyze this big data by taking into account individual variability in genes has enabled the creation of precision (personalized) medicine. We reviewed and highlighted the significance of big data analytics for personalized medicine and health care by focusing mostly on machine learning perspectives on personalized medicine, genomic data models with respect to personalized medicine, the application of data mining algorithms for personalized medicine as well as the challenges we are facing right now in big data analytics. Full article
(This article belongs to the Collection Feature Papers in Molecular Biophysics)
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18 pages, 1540 KB  
Article
Wearable IoTs and Geo-Fencing Based Framework for COVID-19 Remote Patient Health Monitoring and Quarantine Management to Control the Pandemic
by Farman Ullah, Hassan Ul Haq, Jebran Khan, Arslan Ali Safeer, Usman Asif and Sungchang Lee
Electronics 2021, 10(16), 2035; https://doi.org/10.3390/electronics10162035 - 23 Aug 2021
Cited by 32 | Viewed by 6912
Abstract
The epidemic disease of Severe Acute Respiratory Syndrome (SARS) called COVID-19 has become a more frequently active disease. Managing and monitoring COVID-19 patients is still a challenging issue for advanced technologies. The first and foremost critical issue in COVID-19 is to diagnose it [...] Read more.
The epidemic disease of Severe Acute Respiratory Syndrome (SARS) called COVID-19 has become a more frequently active disease. Managing and monitoring COVID-19 patients is still a challenging issue for advanced technologies. The first and foremost critical issue in COVID-19 is to diagnose it timely and cut off the chain of transmission by isolating the susceptible and patients. COVID-19 spreads through close interaction and contact with an infected person. It has affected the entire world, and every country is facing the challenges of having adequate medical facilities along with the availability of medical staff in rural and urban areas that have a high number of patients due to the pandemic. Due to the invasive method of treatment, SARS-COVID is spreading swiftly. In this paper, we propose an intelligent health monitoring framework using wearable Internet of Things (IoT) and Geo-fencing for COVID-19 susceptible and patient monitoring, and isolation and quarantine management to control the pandemic. The proposed system consists of four layers, and each layer has different functionality: a wearable sensors layer, IoT gateway layer, cloud server layer, and client application layer for visualization and analysis. The wearable sensors layer consists of wearable biomedical and GPS sensors for physiological parameters, and GPS and Wi-Fi Received Signal Strength Indicator acquisition for health monitoring and user Geo-fencing. The IoT gateway layer provides a Bluetooth and Wi-Fi based wireless body area network and IoT environment for data transmission anytime and anywhere. Cloud servers use Raspberry Pi and ThingSpeak cloud for data analysis and web-based application layers for remote monitoring based on user consent. The susceptible and patient conditions, real-time sensor’s data, and Geo-fencing enables minimizing the spread through close interaction. The results show the effectiveness of the proposed framework. Full article
(This article belongs to the Special Issue Applications for Smart Cyber Physical Systems)
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20 pages, 1163 KB  
Article
Exploiting Biomedical Sensors for a Home Monitoring System for Paediatric Patients with Congenital Heart Disease
by Massimiliano Donati, Silvia Panicacci, Alessio Ruiu, Stefano Dalmiani, Pierluigi Festa, Lamia Ait-Ali, Francesca Mastorci, Alessandro Pingitore, Wanda Pennè, Luca Fanucci and Sergio Saponara
Technologies 2021, 9(3), 56; https://doi.org/10.3390/technologies9030056 - 31 Jul 2021
Cited by 5 | Viewed by 4173
Abstract
Congenital heart disease, the most frequent malformation at birth, is usually not fatal but leads to multiple hospitalisations and outpatient visits, with negative impact on the quality of life and psychological profile not only of children but also of their families. In this [...] Read more.
Congenital heart disease, the most frequent malformation at birth, is usually not fatal but leads to multiple hospitalisations and outpatient visits, with negative impact on the quality of life and psychological profile not only of children but also of their families. In this paper, we describe the entire architecture of a system for remotely monitoring paediatric/neonatal patients with congenital heart disease, with the final aim of improving quality of life of the whole family and reducing hospital admissions. The interesting vital parameters for the disease are ECG, heart rate, oxygen saturation, body temperature and body weight. They are collected at home using some biomedical sensors specifically selected and calibrated for the paediatric field. These data are then sent to the smart hub, which proceeds with the synchronisation to the remote e-Health care center. Here, the doctors can log and evaluate the patient’s parameters. Preliminary results underline the sensor suitability for children and infants and good usability and data management of the smart-hub technology (E@syCare). In the clinical trial, some patients from the U.O.C. Paediatric and Adult Congenital Cardiology- Monasterio Foundation are enrolled. They receive a home monitoring kit according to the group they belong to. The trial aims to evaluate the effects of the system on quality of life. Psychological data are collected through questionnaires filled in by parents/caregivers in self-administration via the gateway at the beginning and at the end of the study. Results highlight an overall improvement in well-being and sleep quality, with a consequent reduction in anxious and stressful situations during daily life thanks to telemonitoring. At the same time, users reported a good level of usability, ease of data transmission and management of the devices. Full article
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27 pages, 4744 KB  
Article
An Embedded Sensing and Communication Platform, and a Healthcare Model for Remote Monitoring of Chronic Diseases
by Sergio Saponara, Massimiliano Donati, Luca Fanucci and Alessio Celli
Electronics 2016, 5(3), 47; https://doi.org/10.3390/electronics5030047 - 4 Aug 2016
Cited by 24 | Viewed by 12003
Abstract
This paper presents a new remote healthcare model, which, exploiting wireless biomedical sensors, an embedded local unit (gateway) for sensor data acquisition-processing-communication, and a remote e-Health service center, can be scaled in different telemedicine scenarios. The aim is avoiding hospitalization cost and long [...] Read more.
This paper presents a new remote healthcare model, which, exploiting wireless biomedical sensors, an embedded local unit (gateway) for sensor data acquisition-processing-communication, and a remote e-Health service center, can be scaled in different telemedicine scenarios. The aim is avoiding hospitalization cost and long waiting lists for patients affected by chronic illness who need continuous and long-term monitoring of some vital parameters. In the “1:1” scenario, the patient has a set of biomedical sensors and a gateway to exchange data and healthcare protocols with the remote service center. In the “1:N” scenario the use of gateway and sensors is managed by a professional caregiver, e.g., assigned by the Public Health System to a number N of different patients. In the “point of care” scenario the patient, instead of being hospitalized, can take the needed measurements at a specific health corner, which is then connected to the remote e-Health center. A mix of commercially available sensors and new custom-designed ones is presented. The new custom-designed sensors range from a single-lead electrocardiograph for easy measurements taken by the patients at their home, to a multi-channel biomedical integrated circuit for acquisition of multi-channel bio signals, to a new motion sensor for patient posture estimation and fall detection. Experimental trials in real-world telemedicine applications assess the proposed system in terms of easy usability from patients, specialist and family doctors, and caregivers, in terms of scalability in different scenarios, and in terms of suitability for implementation of needed care plans. Full article
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