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4 Results Found

  • Review
  • Open Access
2 Citations
4,835 Views
14 Pages

16 January 2020

Congenital anomalies in phalluses caused by endocrine disruptors have gained a great deal of attention due to its annual increasing rate in males. However, the endocrine-driven molecular regulatory mechanism of abnormal phallus development is complex...

  • Article
  • Open Access
8 Citations
4,476 Views
13 Pages

Androgen and Oestrogen Affect the Expression of Long Non-Coding RNAs During Phallus Development in a Marsupial

  • Yu Chen,
  • Yoko Kuroki,
  • Geoff Shaw,
  • Andrew J. Pask,
  • Hongshi Yu,
  • Atsushi Toyoda,
  • Asao Fujiyama and
  • Marilyn B. Renfree

There is increasing evidence that long non-coding RNAs (lncRNAs) are important for normal reproductive development, yet very few lncRNAs have been identified in phalluses so far. Unlike eutherians, phallus development in the marsupial tammar wallaby...

  • Review
  • Open Access
16 Citations
7,968 Views
16 Pages

Congenital adrenal hyperplasia (CAH) is the most common cause of primary adrenal insufficiency in children and adolescents. It comprises several clinical entities associated with mutations in genes, encoding enzymes involved in cortisol biosynthesis....

  • Review
  • Open Access
9 Citations
6,786 Views
18 Pages

Preclinical and Clinical Research Models of Prostate Cancer: A Brief Overview

  • Debasish Basak,
  • Lisney Gregori,
  • Fatema Johora and
  • Subrata Deb

14 October 2022

The incidence and mortality from prostate cancer (PCa) are on the rise which poses a major public health concern worldwide. In this narrative review, we have summarized the characteristics of major in vitro and in vivo PCa models including their util...