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Keywords = Retinin

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14 pages, 6154 KB  
Article
Bactericidal and Antiviral Bionic Metalized Nanocoatings
by Mikhail Kryuchkov, Jozef Adamcik and Vladimir L. Katanaev
Nanomaterials 2022, 12(11), 1868; https://doi.org/10.3390/nano12111868 - 30 May 2022
Cited by 22 | Viewed by 3780
Abstract
In diverse living organisms, bionanocoatings provide multiple functionalities, to the surfaces they cover. We have, previously, identified the molecular mechanisms of Turing-based self-assembly of insect corneal nanocoatings and developed forward-engineering approaches to construct multifunctional soft bionic nanocoatings, encompassing the Drosophila protein Retinin. Here, [...] Read more.
In diverse living organisms, bionanocoatings provide multiple functionalities, to the surfaces they cover. We have, previously, identified the molecular mechanisms of Turing-based self-assembly of insect corneal nanocoatings and developed forward-engineering approaches to construct multifunctional soft bionic nanocoatings, encompassing the Drosophila protein Retinin. Here, we expand the versatility of the bionic nanocoatings, by identifying and using diverse Retinin-like proteins and different methods of their metallization, using nickel, silver, and copper ions. Comparative assessment, of the resulting bactericidal, antiviral, and cytotoxic properties, identifies the best protocols, to construct safe and anti-infective metalized bionic nanocoatings. Upscaled application of these protocols, to various public surfaces, may represent a safe and economic approach to limit hazardous infections. Full article
(This article belongs to the Special Issue Prospects of Bioinspired and Biomimetic Materials)
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