The phytochemical study of
Cordia exaltata Lam. (Boraginaceae) led to the isolation, through chromatographic techniques, of nineteen secondary metabolites: 8,8'dimethyl-3,4,3',4'-dimethylenedioxy-7-oxo-2,7'cyclolignan (
1), 8,8'-dimethyl-4,5-dimethoxy-3',4'-methylenodioxy-7-oxo-2,7'cyclolignan (
2), sitosterol (
3a), stigmasterol (
3b), sitosterol-3-O-β-d-glucopyranoside (
4a), stigmasterol-3-O-β-d-glucopyranoside (
4b),
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The phytochemical study of
Cordia exaltata Lam. (Boraginaceae) led to the isolation, through chromatographic techniques, of nineteen secondary metabolites: 8,8'dimethyl-3,4,3',4'-dimethylenedioxy-7-oxo-2,7'cyclolignan (
1), 8,8'-dimethyl-4,5-dimethoxy-3',4'-methylenodioxy-7-oxo-2,7'cyclolignan (
2), sitosterol (
3a), stigmasterol (
3b), sitosterol-3-O-β-d-glucopyranoside (
4a), stigmasterol-3-O-β-d-glucopyranoside (
4b), phaeophytin
A (
5), 13
2-hydroxyphaeophytin A (
6), 17
3-ethoxypheophorbide A (
7), 13
2-hydroxy-17
3-ethoxypheophorbide A (
8),
m-methoxy-
p-hydroxybenzaldehyde (
9), (
E)-7-(3,4-dihydroxyphenyl)-7-propenoic acid (
10), 1-benzopyran-2-one (
11), 7-hydroxy-1-benzopyran-2-one (
12), 2,5-bis-(3',4'-methylenedioxiphenyl)-3,4-dimethyltetrahydrofuran (
13), 3,4,5,3',5'-pentamethoxy-1'-allyl-8.O.4'-neolignan (
14), 3,5,7,3',4'-pentahydroxyflavonol (
15), 5,7-dihydroxy-4'-methoxyflavone (
16), 5,8-dihydroxy-7,4’-dimethoxyflavone (
17), kaempherol 3-O-β-d-glucosyl-6''-α-L-ramnopyranoside (
18) and kaempherol 3,7-di-O-α-l-ramnopyranoside (
19). Their structures were identified by
1H and
13C-NMR using one and two-dimensional techniques. In addition, the antimicrobial activity of compounds
1,
2,
13 and
14 against bacteria and fungi are reported here for the first time.
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