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Keywords = Cladiella hirsuta

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13 pages, 555 KB  
Article
Eunicellin-Based Diterpenoids, Hirsutalins S–V, from the Formosan Soft Coral Cladiella hirsuta
by Tzu-Zin Huang, Bo-Wei Chen, Chiung-Yao Huang, Tsong-Long Hwang, Chokkalingam Uvarani, Chang-Feng Dai, Ping-Jyun Sung, Jui-Hsin Su and Jyh-Horng Sheu
Mar. Drugs 2015, 13(5), 2757-2769; https://doi.org/10.3390/md13052757 - 30 Apr 2015
Cited by 15 | Viewed by 6250
Abstract
Four new eunicellin-type hirsutalins S–V (14), along with a known compound (–)-6α-hydroxy polyanthellin A (5), were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxity of [...] Read more.
Four new eunicellin-type hirsutalins S–V (14), along with a known compound (–)-6α-hydroxy polyanthellin A (5), were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxity of compounds 15 against the proliferation of a limited panel of cancer cell lines was measured. Anti-inflammatory activity of compounds 15 was evaluated by measuring their ability in suppressing superoxide anion generation and elastase release in fMLP/ CB-induced human neutrophils. Full article
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12 pages, 777 KB  
Article
Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta
by Tzu-Zin Huang, Bo-Wei Chen, Chiung-Yao Huang, Tsong-Long Hwang, Chang-Feng Dai and Jyh-Horng Sheu
Mar. Drugs 2014, 12(5), 2446-2457; https://doi.org/10.3390/md12052446 - 30 Apr 2014
Cited by 19 | Viewed by 7061
Abstract
New eunicellin-type hirsutalins N–R (15), along with two known eunicellins, (6 and 7) were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxic activity of compounds [...] Read more.
New eunicellin-type hirsutalins N–R (15), along with two known eunicellins, (6 and 7) were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxic activity of compounds 17 against the proliferation of a limited panel of cancer cell lines was measured. The in vitro anti-inflammatory activity of compounds 17 was evaluated by measuring their ability in suppressing superoxide anion generation and elastase release in fMLP/CB-induced human neutrophils. Full article
(This article belongs to the Collection Bioactive Compounds from Marine Invertebrates)
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