Managing Lyme Borreliosis and Post-Lyme Borreliosis Symptoms

Dear Colleagues,

Lyme borreliosis is still sometimes thought to be a difficult to treat or even uncurable disease in spite of well-studied, safe, and effective antibiotic treatment regimens. Misleading or unsubstantiated information about Lyme borreliosis can lead to uncertainty and added stress for patients as well as unnecessary and potentially harmful alternative treatment regimens, often targeting nonspecific symptoms.

Some patients managed in accordance with guidelines for objective or proven Lyme borreliosis may experience persistent or intermittent nonspecific symptoms after treatment. These post-treatment symptoms have, thus far, not been shown to be due to persistent infection with Borrelia burgdorferi sensu lato. Consequently, other potential etiologies continue to be explored, including immune, metabolic, and inflammatory processes. Further research and data are still needed to clarify the pathophysiology of Lyme borreliosis and identify possible adjunctive treatments to improve outcomes in the minority of patients with incomplete response to current guideline-based treatment regimens.

For this Special Issue, we encourage you to submit research or review papers on treatment outcome in patients with different manifestations of Lyme borreliosis. Papers exploring the etiology of Lyme borreliosis-associated and post-Lyme borreliosis subjective symptoms are also welcome. With your participation, we aim to further elucidate the pathogenesis of these symptoms and identify strategies to manage them.

Dr. Daša Stupica
Dr. Stefan Collinet-Adler
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tropical Medicine and Infectious Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Lyme borreliosis
• treatment outcome
• post-Lyme borreliosis symptoms
• nonspecific symptoms