Screening for Fetal and Maternal Diseases Using Molecular Biochemical and Biophysical Markers
A special issue of Reproductive Medicine (ISSN 2673-3897).
Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 15790
Special Issue Editor
Special Issue Information
Dear Colleagues,
In the past 40 years, there has been a remarkable progression in the availability of tools and strategies for screening and diagnosis of fetal–maternal disorders. In this field, a major role was established for cell-free fetal DNA as well as for several other less known circulating nucleic acids in maternal plasma (CNAPS) such as mRNA, miRNA and other RNA species, which are currently investigated due to their potential usefulness in the screening of various fetal–maternal conditions. Moreover, new technologies are emerging and becoming available in the landscape of prenatal screening, such as the “trio” non-invasive whole exome sequencing (WES). Novel strategies and customized algorithms applied to biochemical markers, ultrasound, or combinations of both have recently been proposed and clinically implemented, improving the detection of high-risk pregnancies. Finally, different methods assessing maternal hemodynamics are under investigation for possible clinical application in screening, diagnosis, or personalized treatments of hypertensive disorders of pregnancy.
This Special Issue focuses on the latest research progress involving all aspects of screening in prenatal medicine, including development of new ideas, models, and techniques, as well as all advancements enhancing screening performance.
Dr. Danila Morano
Guest Editor
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Keywords
- circulating nucleic acids in maternal blood
- placental markers
- ultrasounds
- multivariable analyses
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