Research Advances in Blood Purification: New Techniques, Drugs and Indications

Dear Colleagues,

Blood purification is an extracorporeal therapeutic modality that facilitates the removal of deleterious substances from the human body via extracorporeal circulation, with the goals of the treatment and maintenance of fluid balance. The principal patient populations that benefit from this technology include those with renal disorders (such as end-stage chronic kidney disease or acute renal failure), individuals suffering from poisoning (due to drugs or heavy metals), patients with metabolic disorders (such as hyperuricemia or hypercholesterolemia), and individuals with immune-mediated diseases (including systemic lupus erythematosus or myasthenia gravis). Moreover, blood purification therapy may be indicated for patients with hepatic failure, severe infectious diseases, and stress-related injuries. Ongoing refinements in blood purification technologies have significantly enhanced patient outcomes and extended life expectancies. These advancements encompass improvements in blood purification machinery and materials, the optimization of vascular access techniques, the introduction of innovative blood purification methods, and the development of personalized treatment plans. However, both short-term and long-term blood purification treatments entail risks of adverse effects, which underscore the importance of the vigilant prevention and management of related complications. Furthermore, advancements in artificial organ and cell transplantation have opened new avenues of research within the realm of blood purification. Given its proven clinical efficacy, the application of blood purification technology has been broadened to encompass an array of additional indications. In summary, blood purification technology is in a state of perpetual evolution, striving for enhanced safety, improved efficacy, and greater personalization, thereby offering superior treatment options for a wide range of severe medical conditions.

This topic is dedicated to clinical research concerning novel technologies, pharmacotherapies, and the associated complications of blood purification. Submissions that focus on cutting-edge research regarding artificial kidney and cell transplantation techniques are also encouraged, as are discussions on the application of blood purification methodologies to emerging indications. The topics of interest include, but are not limited to, the following areas:

1. Personalized blood purification solutions.
2. Risk of infection, coagulation, and other complications during blood purification.
3. Health effects of long-term blood purification and management practices.
4. Current status of development of artificial kidney and cell transplantation techniques.
5. Blood purification techniques in new indications.
6. Dialysis and nutritional support.
7. The effects of dialysis on drug metabolism and recommendations for safe use.

Dr. Zibo Xiong
Dr. Guang Yang
Dr. Fengping Zheng
Guest Editors

Manuscript Submission Information

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• chronic kidney disease
• acute kidney disease
• dialysis
• vascular access
• nursing
• sepsis