Advances in Enzyme Inhibition: Biophysical and Experimental Approaches
A special issue of Biophysica (ISSN 2673-4125).
Deadline for manuscript submissions: 31 August 2025 | Viewed by 388
Special Issue Editor
Interests: biochemistry; enzymology; drug discovery; SELEX (systematic evolution of ligands by exponential enrichment); in vitro selection technique
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Enzymes are major targets in drug development due to their critical roles in biological processes. Investigating enzyme characteristics through purification, kinetic studies, stability profiling, and structural analysis is essential for understanding their functions and for guiding the design of more effective inhibitors. Both experimental and computational approaches—such as molecular docking and molecular dynamics—are crucial for achieving a comprehensive understanding.
This Special Issue, “Advances in Enzyme Inhibition: Biophysical and Experimental Approaches”, aims to highlight recent progress in experimental and/or computational strategies for enzyme inhibition. Contributions that utilize biophysical methods or integrated approaches are especially encouraged.
Key words for the topics: Enzyme purification, enzyme stabilization, enzyme inhibitors, Mechanistic studies of enzyme activity, Structural and conformational analyses, computational modeling of enzyme-inhibitor interactions.
We invite original research and reviews that advance our understanding of enzyme inhibition.
Prof. Dr. Sung-Kun (Sean) Kim
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biophysica is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- enzyme purification
- enzyme stabilization
- enzyme inhibitors
- mechanistic studies of enzyme activity
- structural and conformational analyses
- computational modeling of enzyme-inhibitor interactions
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