Novel Chemical and Biological Approaches to Understanding the Bacterial Cell Envelope
A special issue of Bacteria (ISSN 2674-1334).
Deadline for manuscript submissions: closed (4 March 2024) | Viewed by 546
Special Issue Editors
Interests: mycobacterium; cell envelope; antimicrobial resistance; click chemistry; bacteriophage; peptide; protein function
Interests: chimeric antibodies; multispecifics; lectins; antimicrobial peptides; antimicrobial resistance
Interests: biochemistry; bioconjugation; peptide; nanobody; cell signaling; receptors
Special Issue Information
Dear Colleagues,
The bacterial cell envelope is a multilayered structure composed of carbohydrates, lipids, and proteins linked either covalently or non-covalently to one another.
The bacterial cell envelope plays a critical role in maintaining cell integrity, regulating the exchange of molecules with the external environment, and facilitating interactions with host cells in bacterial pathogenesis. In addition, it remains the prime target for most antibiotics and the component of choice in cell-labeling techniques for studying the phenomena such as cell division, chemotaxis, and cell wall metabolism. Therefore, understanding the intricate architecture and dynamics of the bacterial cell envelope is crucial for developing effective therapeutic strategies against bacterial infections.
Numerous molecular tools are known to date that function as antibiotics, modifiers, dyes or stains. In the last decade, significant advancements have been made in the field of bioconjugation, which now provides a new path for the synthesis of molecules that can be used in several bacteriological applications, e.g., targeted killing, selective labeling, cell-specific delivery, and cell metabolism study.
This Special Issue of Bacteria focuses on the bacterial cell envelope and biological or chemical tools that have been developed or used to study its different aspects.
Dr. Amol Pohane
Dr. Rashmi Kumariya
Dr. Shubhra Saha
Guest Editors
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Keywords
- cell envelope
- bioconjugates
- molecular tools
- antibiotic resistance
- biochemistry
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