Gynecologic oncology poses a serious threat to women’s health. Breakthroughs in its diagnosis and treatment research are crucial for improving patient outcomes and strengthening disease prevention and control. The Journal of Clinical Medicine (JCM, ISSN: 2077-0383) has compiled open access research from the past two years in this field. We cordially invite you to read these highly cited papers. For detailed information on the papers, please click the links below. Multiple Special Issues on related topics are currently open for submission. We look forward to your engagement and participation.

1. “Endometriosis-Related Ovarian Cancer: Where Are We Now? A Narrative Review towards a Pragmatic Approach”
by Gabriele Centini, Giorgia Schettini, Emilio Pieri, Matteo Giorgi, Lucia Lazzeri, Francesco Giuseppe Martire, Virginia Mancini, Diego Raimondo, Renato Seracchioli, Nassir Habib et al.
J. Clin. Med. 2024, 13(7), 1933; https://doi.org/10.3390/jcm13071933
Full text available online: https://www.mdpi.com/2077-0383/13/7/1933

2. “New Frontiers in Locally Advanced Cervical Cancer Treatment”
by Roberta Massobrio, Lavinia Bianco, Beatrice Campigotto, Daniela Attianese, Elisa Maisto, Maria Pascotto, Maria Grazia Ruo Redda and Annamaria Ferrero
J. Clin. Med. 2024, 13(15), 4458; https://doi.org/10.3390/jcm13154458
Full text available online: https://www.mdpi.com/2077-0383/13/15/4458

3. “Hormone Replacement Therapy in Post-Menopause Hormone-Dependent Gynecological Cancer Patients: A Narrative Review”
by Paola Villa, Valentina Elisabetta Bounous, Inbal Dona Amar, Federica Bernardini, Margherita Giorgi, Daniela Attianese, Annamaria Ferrero, Marika D’Oria and Giovanni Scambia
J. Clin. Med. 2024, 13(5), 1443; https://doi.org/10.3390/jcm13051443
Full text available online: https://www.mdpi.com/2077-0383/13/5/1443

4. “The Role of Adjuvant Therapy for the Treatment of Micrometastases in Endometrial Cancer: A Systematic Review and Meta-Analysis”
by Carlo Ronsini, Stefania Napolitano, Irene Iavarone, Pietro Fumiento, Maria Giovanna Vastarella, Antonella Reino, Rossella Molitierno, Lugi Cobellis, Pasquale De Franciscis and Stefano Cianci
J. Clin. Med. 2024, 13(5), 1496; https://doi.org/10.3390/jcm13051496
Full text available online: https://www.mdpi.com/2077-0383/13/5/1496

5. “Surgical Outcomes of da Vinci Xi™ and da Vinci SP™ for Early-Stage Endometrial Cancer in Patients Undergoing Hysterectomy”
by Motoki Matsuura, Sachiko Nagao, Shoko Kurokawa, Masato Tamate, Taishi Akimoto and Tsuyoshi Saito
J. Clin. Med. 2024, 13(10), 2864; https://doi.org/10.3390/jcm13102864
Full text available online: https://www.mdpi.com/2077-0383/13/10/2864

6. “The Assessment of Sentinel Lymph Node Mapping Methods in Endometrial Cancer”
by Wiktor Szatkowski, Karolina Pniewska, Maja Janeczek, Janusz Ryś, Tomasz Banaś, Konrad Muzykiewicz, Ewa Iwańska, Jerzy Jakubowicz, Kazimierz Karolewski, Agnieszka Szadurska et al.
J. Clin. Med. 2025, 14(3), 676; https://doi.org/10.3390/jcm14030676
Full text available online: https://www.mdpi.com/2077-0383/14/3/676

7. “Screening Strategies to Improve Early Diagnosis in Endometrial Cancer”
by Silvia Cabrera, Irene de la Calle, Sonia Baulies, Antonio Gil-Moreno and Eva Colas
J. Clin. Med. 2024, 13(18), 5445; https://doi.org/10.3390/jcm13185445
Full text available online: https://www.mdpi.com/2077-0383/13/18/5445

8. “The Association Between Metabolic Syndrome and the Risk of Endometrial Cancer in Pre- and Post-Menopausal Women: A UK Biobank Study”
by Rebecca Karkia, Gideon Maccarthy, Annette Payne, Emmanouil Karteris, Raha Pazoki and Jayanta Chatterjee
J. Clin. Med. 2025, 14(3), 751; https://doi.org/10.3390/jcm14030751
Full text available online: https://www.mdpi.com/2077-0383/14/3/751

9. “PD-1 and PD-L1 Expression in Endometrial Cancer: A Systematic Review of the Literature”
by Orazio De Tommasi, Matteo Marchetti, Marta Tripepi, Sofia Bigardi, Giosuè Giordano Incognito, Valentina Tuninetti, Emma Facchetti, Giulia Tasca, Marco Noventa, Carlo Saccardi et al.
J. Clin. Med. 2025, 14(2), 401; https://doi.org/10.3390/jcm14020401
Full text available online: https://www.mdpi.com/2077-0383/14/2/401

10. “Comprehensive Review of Endometrial Cancer: New Molecular and FIGO Classification and Recent Treatment Changes”
by Maria-Bianca Anca-Stanciu, Andrei Manu, Maria Victoria Olinca, Cătălin Coroleucă, Diana-Elena Comandașu, Ciprian Andrei Coroleuca, Calina Maier and Elvira Bratila
J. Clin. Med. 2025, 14(4), 1385; https://doi.org/10.3390/jcm14041385
Full text available online: https://www.mdpi.com/2077-0383/14/4/1385