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Volume 54, IOCAG 2025
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Biol. Life Sci. Forum, 2025, ISFMS

The 5th International Symposium on Frontiers in Molecular Science

Kyoto, Japan | 26–29 August 2025

Volume Editors:

Yoshinori Marunaka, Kyoto Industrial Health Association, Japan
Masayuki Takahashi, Kyoto Prefectural University, Japan
Yusaku Iwasaki, Kyoto Prefectural University, Japan
Akiyuki Taruno, Kyoto Prefectural University of Medicine, Japan
Atsushi Shiozaki, Kyoto Prefectural University of Medicine, Japan

Number of Papers: 1
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Cover Story (view full-size image): The 5th International Symposium on Frontiers in Molecular Science (ISFMS 2025) was held in Kyoto, Japan, between 26 and 29 August 2025. The symposium presented outstanding research results that [...] Read more.
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8 pages, 420 KB  
Proceeding Paper
Natural Product-Based Discovery of Antibacterial Agents from Sophora tomentosa L. to Tackle Drug Resistance
by Supattra Poeaim, Patcharanun Laowklang, Narumon Tangthirasunun and Thanarak Chantaraprasit
Biol. Life Sci. Forum 2025, 53(1), 1; https://doi.org/10.3390/blsf2025053001 - 19 Nov 2025
Viewed by 173
Abstract
The rapid emergence of antimicrobial resistance (AMR) threatens global health by reducing the effectiveness of current antibiotics. Natural products remain an essential source of structurally diverse compounds with therapeutic potential. This study’s methanolic extracts of Sophora tomentosa L., a leguminous plant with traditional [...] Read more.
The rapid emergence of antimicrobial resistance (AMR) threatens global health by reducing the effectiveness of current antibiotics. Natural products remain an essential source of structurally diverse compounds with therapeutic potential. This study’s methanolic extracts of Sophora tomentosa L., a leguminous plant with traditional medicinal uses, were fractionated by liquid–liquid extraction and column chromatography. Dichloromethane and ethyl acetate fractions from leaves and seeds exhibited antibacterial activity against Kocuria rhizophila and Bacillus cereus. GC–MS profiling revealed alkaloids (e.g., matrine), flavonoids (e.g., catechin), phthalic acid derivatives, and fatty acids, supporting the potential of S. tomentosa as a source of novel antibacterial agents. Full article
(This article belongs to the Proceedings of The 5th International Symposium on Frontiers in Molecular Science)
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