Synergizing Immune Balance: Curcumin Gold Nanoparticles and Ultrasound Irradiation for Macrophage Down-Regulation
Abstract
:1. Introduction
2. Materials and Methods
2.1. Synthesis of Gold Nanoparticles Associated with Curcumin [CurAuNPs]
2.2. Nanoparticles Characterization
2.3. Study of Singlet Oxygen Released by Ultrasound Irradiation
2.4. Cell Culture
2.5. Cytotoxicity of Nanoparticles
2.6. Ultrasound Irradiation
2.7. Statistical Analysis
3. Results
3.1. Synthesis and Characterization of CurAuNPs
3.2. Singlet Oxygen [1O2] Release from CurAuNPs under Ultrasound Irradiation
3.3. Cell Viability Study
3.4. Ultrasound Irradiation
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Zeta Potential (mV) | Size (nm) | |
---|---|---|
CurAu | −19.16 | 9.6 nm |
CurAu PEG | −23.00 | 20.0 nm |
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Teixeira, B.H.; Gonçalves, K.d.O.; Vieira, D.P.; Coronato Courrol, L. Synergizing Immune Balance: Curcumin Gold Nanoparticles and Ultrasound Irradiation for Macrophage Down-Regulation. AppliedChem 2024, 4, 70-85. https://doi.org/10.3390/appliedchem4010006
Teixeira BH, Gonçalves KdO, Vieira DP, Coronato Courrol L. Synergizing Immune Balance: Curcumin Gold Nanoparticles and Ultrasound Irradiation for Macrophage Down-Regulation. AppliedChem. 2024; 4(1):70-85. https://doi.org/10.3390/appliedchem4010006
Chicago/Turabian StyleTeixeira, Bruna Henrique, Karina de Oliveira Gonçalves, Daniel Perez Vieira, and Lilia Coronato Courrol. 2024. "Synergizing Immune Balance: Curcumin Gold Nanoparticles and Ultrasound Irradiation for Macrophage Down-Regulation" AppliedChem 4, no. 1: 70-85. https://doi.org/10.3390/appliedchem4010006