Corneal Edema from Accidental Instillation of Stamper Ink Mistaken for Artificial Tears: A Case Report

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

 This study reported an ocular trauma caused by inadvertently instilling stamper ink refill into both eyes  instead of artificial tears, This case report adds the spectrum of the continuing problem of chemical ocular trauma. The manuscript is well written but the conponents of the  stamper ink and concentration should be included in the manuscript is avaliable.

Besides,

1 "intraocular pressure was normal in the BE (9.7 and 9.0, respectively)", the normal range of IOP should be 10-21mmHg.

2 "The patient had an endothelial cell density test and showed normal results (RE:1952 cells/mm2 and LE:  cells/mm2, respectively "， normally ,  endothelial cell density should be above 2000 cells/mm2.

3 "After the injury, keratocytes are migrated to repopulate the cornea, starting from the posterior stroma.", please provide the reference for this statement.

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

This is a single case report of corneal injury from accidental application of stamper pad ink when application of artificial tears was intended. The case description is straight forward.  Some description of the intended use of the ink might be useful, i.e., how is it applied for inking. There are multiple relatively minor errors in English language usage. In line 62, provide the pH number rather than just "alkaline pH". In line 57, I believe "Pantocaine" should be "Pontocaine".  In line 111-2, stating that the endothelial cell counts were normal, at 1952 and 987, is incorrect.  The 987 value is clearly below normal, though not likely from the chemical injury.

 

Comments on the Quality of English Language

There are multiple minor English usage errors.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 1 Report

Comments and Suggestions for Authors

The authors has responsed to all of the comments from reviewers and the quality of the manuscript is good for publication now.

Reviewer 2 Report

Comments and Suggestions for Authors

The authors have responded adequately to my prior concerns.