Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review
Abstract
:1. Introduction
2. Materials and Methods
- -
- Articles not written in English,
- -
- Narrative reviews and systematic reviews,
- -
- Studies that did not focus on physical chemical aspects, biocompatibility and sealing ability,
- -
- Studies that only treated a class of cements, or that only reported data and information for one type of endodontic cement,
- -
- Studies published before 2010.
3. Results
- Chemical-physical properties
- Cytotoxicity and cell migration
- Inflammatory response
- Mineralizing and osteogenic activity
- Ion release
- Filling efficiency of root canals
4. Discussion
4.1. Chemical-Physical Properties
4.2. Cytotoxicity and Cell Migration
4.3. Inflammatory Response
4.4. Mineralizing and Osteogenic Activity
4.5. Ion Release
4.6. Root Canal Filling Efficiency
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
- Li, G.-H.; Niu, L.-N.; Zhang, W.; Olsen, M.; De-Deus, G.; Eid, A.A.; Chen, J.-H.; Pashley, D.H.; Tay, F.R. Ability of new obturation materials to improve the seal of the root canal system: A review. Acta Biomater. 2014, 10, 1050–1063. [Google Scholar] [CrossRef] [Green Version]
- Buonavoglia, A.; Lauritano, D.; Perrone, D.; Ardito, F.; Troiano, G.; Dioguardi, M.; Candotto, V.; Silvestre, F.J.; Muzio, L.L. Evaluation of chemical-physical properties and cytocompatibility of TheraCal LC. J. Boil. Regul. Homeost. Agents 2017, 31, 1–9. [Google Scholar]
- Troiano, G.; Perrone, D.; Dioguardi, M.; Buonavoglia, A.; Ardito, F.; Muzio, L.L. In vitro evaluation of the cytotoxic activity of three epoxy resin-based endodontic sealers. Dent. Mater. J. 2018, 37, 374–378. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Dioguardi, M.; Perrone, D.; Troiano, G.; Laino, L.; Ardito, F.; Lauritano, F.; Cicciù, M.; Muzio, L.L. Cytotoxicity evaluation of five different dual-cured resin cements used for fiber posts cementation. Int. J. Clin. Exp. Med. 2015, 8, 9327–9333. [Google Scholar] [PubMed]
- Friedman, S.; Torneck, C.D.; Komorowski, R.; Ouzounian, Z.; Syrtash, P.; Kaufman, A. In vivo model for assessing the functional efficacy of endodontic filling materials and techniques. J. Endod. 1997, 23, 557–561. [Google Scholar] [CrossRef]
- Arthanari, K.K.; Palanivelu, C.R.; Ravi, V.; Sivakumar, A.A.; Sivakumar, J.S.; Prasad, A.S. An in vitro comparative evaluation of distribution of three different sealers by single-cone obturation technique. J. Pharm. Bioallied Sci. 2019, 11, S438–S441. [Google Scholar] [CrossRef]
- Restrepo-Restrepo, F.A.; Cañas-Jiménez, S.J.; Romero-Albarracín, R.D.; Villa-Machado, P.A.; Pérez-Cano, M.I.; Tobón-Arroyave, S. Prognosis of root canal treatment in teeth with preoperative apical periodontitis: A study with cone-beam computed tomography and digital periapical radiography. Int. Endod. J. 2019, 52, 1533–1546. [Google Scholar] [CrossRef]
- Orstavik, D.; Kerekes, K.; Eriksen, H.M. Clinical performance of three endodontic sealers. Dent. Traumatol. 1987, 3, 178–186. [Google Scholar] [CrossRef] [PubMed]
- Grossman, L.I. Prevention in Endodontic Practice. J. Am. Dent. Assoc. 1971, 82, 395–396. [Google Scholar] [CrossRef]
- Almeida, L.H.S.; Moraes, R.R.; Morgental, R.D.; Pappen, F.G. Are Premixed Calcium Silicate–based Endodontic Sealers Comparable to Conventional Materials? A Systematic Review of In Vitro Studies. J. Endod. 2017, 43, 527–535. [Google Scholar] [CrossRef]
- Giacomino, C.M.; Wealleans, J.A.; Kuhn, N.; Diogenes, A. Comparative Biocompatibility and Osteogenic Potential of Two Bioceramic Sealers. J. Endod. 2019, 45, 51–56. [Google Scholar] [CrossRef]
- Donnermeyer, D.; Bürklein, S.; Dammaschke, T.; Schäfer, E. Endodontic sealers based on calcium silicates: A systematic review. Odontology 2019, 107, 421–436. [Google Scholar] [CrossRef] [PubMed]
- Raghavendra, S.S.; Jadhav, G.R.; Gathani, K.M.; Kotadia, P. Bioceramics in Endodontics—A Review. J. Istanb. Univ. Fac. Dent. 2017, 51, S128–S137. [Google Scholar] [CrossRef] [PubMed]
- Jitaru, S.; Hodisan, I.; Timis, L.; Lucian, A.; Bud, M. The Use of Bioceramics in Endodontics—Literature Review. Med. Pharm. Rep. 2016, 89, 470–473. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Kim, U.-S.; Shin, S.-J.; Chang, S.W.; Yoo, H.-M.; Oh, T.-S.; Park, D.S. In vitro evaluation of bacterial leakage resistance of an ultrasonically placed mineral trioxide aggregate orthograde apical plug in teeth with wide open apexes: A preliminary study. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol. 2009, 107, e52–e56. [Google Scholar] [CrossRef]
- Aslan, T.; Esim, E.; Üstün, Y.; Özkan, H.D. Evaluation of Stress Distributions in Mandibular Molar Teeth with Different Iatrogenic Root Perforations Repaired with Biodentine or Mineral Trioxide Aggregate: A Finite Element Analysis Study. J. Endod. 2020. [Google Scholar] [CrossRef]
- Mir, S.; Gautam, A.; Batra, R.; Soni, S.; Lata, K. Evaluation of Antimicrobial Efficacy of Root Canal Sealers against Enterococcus faecalis: A Comparative Study. J. Contemp. Dent. Pract. 2018, 19, 680–683. [Google Scholar] [CrossRef]
- Khalil, W.A.; Alghamdi, F.; Aljahdali, E. Strengthening effect of bioceramic cement when used to repair simulated internal resorption cavities in endodontically treated teeth. Dent. Med. Probl. 2020, 57, 165–169. [Google Scholar] [CrossRef] [PubMed]
- Lim, M.; Jung, C.; Shin, D.-H.; Cho, Y.-B.; Song, M. Calcium silicate-based root canal sealers: A literature review. Restor. Dent. Endod. 2020, 45, e35. [Google Scholar] [CrossRef]
- Zordan-Bronzel, C.L.; Torres, F.F.E.; Tanomaru-Filho, M.; Chávez-Andrade, G.M.; Bosso-Martelo, R.; Guerreiro-Tanomaru, J.M. Evaluation of Physicochemical Properties of a New Calcium Silicate-based Sealer, Bio-C Sealer. J. Endod. 2019, 45, 1248–1252. [Google Scholar] [CrossRef] [PubMed]
- Chen, B.; Haapasalo, M.; Mobuchon, C.; Li, X.; Ma, J.; Shen, Y. Cytotoxicity and the Effect of Temperature on Physical Properties and Chemical Composition of a New Calcium Silicate–based Root Canal Sealer. J. Endod. 2020, 46, 531–538. [Google Scholar] [CrossRef]
- Torres, F.F.E.; Zordan-Bronzel, C.L.; Guerreiro-Tanomaru, J.M.; Chávez-Andrade, G.M.; Pinto, J.C.; Tanomaru-Filho, M. Effect of immersion in distilled water or phosphate-buffered saline on the solubility, volumetric change and presence of voids within new calcium silicate-based root canal sealers. Int. Endod. J. 2020, 53, 385–391. [Google Scholar] [CrossRef]
- Seo, D.-G.; Lee, D.; Kim, Y.-M.; Song, D.; Kim, S.-Y. Biocompatibility and Mineralization Activity of Three Calcium Silicate-Based Root Canal Sealers Compared to Conventional Resin-Based Sealer in Human Dental Pulp Stem Cells. Materials 2019, 12, 2482. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Lee, J.K.; Kim, S.; Lee, S.; Kim, H.-C.; Kim, E. In Vitro Comparison of Biocompatibility of Calcium Silicate-Based Root Canal Sealers. Materials 2019, 12, 2411. [Google Scholar] [CrossRef] [Green Version]
- López-García, S.; Myong-Hyun, B.; Lozano, A.; García-Bernal, D.; Forner, L.; Llena, C.; Guerrero-Gironés, J.; Murcia, L.; Rodríguez-Lozano, F.J. Cytocompatibility, bioactivity potential, and ion release of three premixed calcium silicate-based sealers. Clin. Oral Investig. 2020, 24, 1749–1759. [Google Scholar] [CrossRef]
- Gaudin, A.; Tolar, M.; Peters, O.A. Cytokine Production and Cytotoxicity of Calcium Silicate–based Sealers in 2- and 3-dimensional Cell Culture Models. J. Endod. 2020, 46, 818–826. [Google Scholar] [CrossRef] [PubMed]
- Sanz, J.L.; López-García, S.; Lozano, A.; Pecci-Lloret, M.P.; Llena, C.; Guerrero-Gironés, J.; Rodríguez-Lozano, F.J.; Forner, L. Microstructural composition, ion release, and bioactive potential of new premixed calcium silicate–based endodontic sealers indicated for warm vertical compaction technique. Clin. Oral Investig. 2020, 1–12. [Google Scholar] [CrossRef] [PubMed]
- Rodríguez-Lozano, F.; Collado-González, M.; Tomás-Catalá, C.; García-Bernal, D.; López, S.; Oñate-Sánchez, R.; Moraleda, J.; Murcia, L. GuttaFlow Bioseal promotes spontaneous differentiation of human periodontal ligament stem cells into cementoblast-like cells. Dent. Mater. 2019, 35, 114–124. [Google Scholar] [CrossRef] [PubMed]
- Silva, E.C.A.; Tanomaru-Filho, M.; Da Silva, G.F.; Delfino, M.M.; Cerri, P.S.; Guerreiro-Tanomaru, J.M. Biocompatibility and Bioactive Potential of New Calcium Silicate–based Endodontic Sealers: Bio-C Sealer and Sealer Plus BC. J. Endod. 2020. [Google Scholar] [CrossRef]
- Kim, S.R.; Kwak, S.W.; Lee, J.-K.; Goo, H.-J.; Ha, J.-H.; Kim, H.-C. Efficacy and retrievability of root canal filling using calcium silicate-based and epoxy resin-based root canal sealers with matched obturation techniques. Aust. Endod. J. 2019, 45, 337–345. [Google Scholar] [CrossRef]
- Milanovic, I.; Milovanovic, P.; Antonijevic, D.; Dzeletovic, B.; Djuric, M.; Miletic, V. Immediate and Long-Term Porosity of Calcium Silicate–Based Sealers. J. Endod. 2020, 46, 515–523. [Google Scholar] [CrossRef] [PubMed]
- Kim, J.C.; Moe, M.M.K.; Kim, S.K. A micro-computed tomographic evaluation of root canal filling with a single gutta-percha cone and calcium silicate sealer. Restor. Dent. Endod. 2020, 45, e18. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Versiani, M.; Rached-Junior, F.J.A.; Kishen, A.; Pécora, J.D.; Silva-Sousa, Y.T.C.; de Sousa-Neto, M.D. Zinc Oxide Nanoparticles Enhance Physicochemical Characteristics of Grossman Sealer. J. Endod. 2016, 42, 1804–1810. [Google Scholar] [CrossRef] [PubMed]
- Jang, J.-H.; Lee, C.-O.; Kim, H.-J.; Kim, S.G.; Lee, S.-W.; Kim, S.-Y. Enhancing Effect of Elastinlike Polypeptide-based Matrix on the Physical Properties of Mineral Trioxide Aggregate. J. Endod. 2018, 44, 1702–1708. [Google Scholar] [CrossRef] [PubMed]
- Siqueira, J.F.; Fraga, R.C.; Garcia, P.F. Evaluation of sealing ability, pH and flow rate of three calcium hydroxide-based sealers. Dent. Traumatol. 1995, 11, 225–228. [Google Scholar] [CrossRef] [PubMed]
- Viapiana, R.; Flumignan, D.L.; Guerreiro-Tanomaru, J.M.; Camilleri, J.; Tanomaru-Filho, M. Physicochemical and mechanical properties of zirconium oxide and niobium oxide modified Portland cement-based experimental endodontic sealers. Int. Endod. J. 2013, 47, 437–448. [Google Scholar] [CrossRef]
- Al-Haddad, A.; Ab Aziz, Z.A.C. Bioceramic-Based Root Canal Sealers: A Review. Int. J. Biomater. 2016, 2016, 1–10. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Vivan, R.R.; Ordinola-Zapata, R.; Bramante, C.M.; Bernardineli, N.; Garcia, R.B.; Duarte, M.A.H.; De Moraes, I.G. Evaluation of the radiopacity of some commercial and experimental root-end filling materials. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol. 2009, 108, e35–e38. [Google Scholar] [CrossRef]
- Urban, K.; Neuhaus, J.; Donnermeyer, D.; Schäfer, E.; Dammaschke, T. Solubility and pH Value of 3 Different Root Canal Sealers: A Long-term Investigation. J. Endod. 2018, 44, 1736–1740. [Google Scholar] [CrossRef]
- Dioguardi, M.; Di Gioia, G.; Gaetano, I.; Arena, C.; Caponio, V.C.A.; Russo, L.L.; Zhurakivska, K.; Adipietro, I.; Troiano, G.; Muzio, L.L. Inspection of the Microbiota in Endodontic Lesions. Dent. J. 2019, 7, 47. [Google Scholar] [CrossRef] [Green Version]
- Dioguardi, M.; Di Gioia, G.; Illuzzi, G.; Laneve, E.; Cocco, A.; Troiano, G. Endodontic irrigants: Different methods to improve efficacy and related problems. Eur. J. Dent. 2018, 12, 459–466. [Google Scholar] [CrossRef] [Green Version]
- Kwolek-Mirek, M.; Zadrag-Tecza, R. Comparison of methods used for assessing the viability and vitality of yeast cells. FEMS Yeast Res. 2014, 14, 1068–1079. [Google Scholar] [CrossRef]
- Singh, A.V.; Kishore, V.; Santomauro, G.; Yasa, O.; Bill, J.; Sitti, M. Mechanical Coupling of Puller and Pusher Active Microswimmers Influences Motility. Langmuir 2020, 36, 5435–5443. [Google Scholar] [CrossRef]
- Semun, S.; Kim, J.H.; Kim, N. Proinflammatory Cytokines Modulating Osteoclast Differentiation and Function. J. Rheum. Dis. 2016, 23, 148–153. [Google Scholar]
- Langub, M.C.; Koszewski, N.J.; Turner, H.V.; Monier-Faugere, M.-C.; Geng, Z.; Malluche, H.H. Bone resorption and mRNA expression of IL-6 and IL-6 receptor in patients with renal osteodystrophy. Kidney Int. 1996, 50, 515–520. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Mantovani, A.; Sica, A.; Sozzani, S.; Allavena, P.; Vecchi, A.; Locati, M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004, 25, 677–686. [Google Scholar] [CrossRef] [PubMed]
- Ma, J.; Shen, Y.; Stojicic, S.; Haapasalo, M. Biocompatibility of Two Novel Root Repair Materials. J. Endod. 2011, 37, 793–798. [Google Scholar] [CrossRef]
- D’Antò, V.; Di Caprio, M.P.; Ametrano, G.; Simeone, M.; Rengo, S.; Spagnuolo, G. Effect of Mineral Trioxide Aggregate on Mesenchymal Stem Cells. J. Endod. 2010, 36, 1839–1843. [Google Scholar] [CrossRef]
- Singh, A.V. Top-Down versus Bottom-Up Nanoengineering Routes to Design Advanced Oropharmacological Products. Curr. Pharm. Des. 2016, 22, 1534–1545. [Google Scholar] [CrossRef]
- Bruderer, M.; Richards, R.G.; Alini, M.; Stoddart, M.J. Role and regulation of RUNX2 in osteogenesis. Eur. Cells Mater. 2014, 28, 269–286. [Google Scholar] [CrossRef]
- Eveline, P.; Yoshihara, K.; De Munck, J.; Cokic, S.; Pongprueksa, P.; Putzeys, E.; Pedano, M.; Chen, Z.; Van Landuyt, K.; Van Meerbeek, B. Modified tricalcium silicate cement formulations with added zirconium oxide. Clin. Oral Investig. 2017, 21, 895–905. [Google Scholar] [CrossRef]
- Rajasekharan, S.; Vercruysse, C.; Martens, L.; Verbeeck, R. Effect of Exposed Surface Area, Volume and Environmental pH on the Calcium Ion Release of Three Commercially Available Tricalcium Silicate Based Dental Cements. Materials 2018, 11, 123. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Waltimo, T.; Trope, M.; Haapasalo, M.; Ørstavik, D. Clinical Efficacy of Treatment Procedures in Endodontic Infection Control and One Year Follow-Up of Periapical Healing. J. Endod. 2005, 31, 863–866. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Dabaj, P.; Kalender, A.; Eldeniz, A.U. Push-Out Bond Strength and SEM Evaluation in Roots Filled with Two Different Techniques Using New and Conventional Sealers. Materials 2018, 11, 1620. [Google Scholar] [CrossRef] [Green Version]
Author, Date, Journal | Materials | Features Analyzed |
---|---|---|
Zordan-Bronzel, 2019, Journal of endodontics [20] | Bio-C Sealer, TotalFill BC Sealer, AH Plus | chemical-physical properties |
Chen, 2020, Journal of endodontics [21] | EndoSequence BC Sealer, EndoSequence BC Sealer HiFlow | chemical-physical properties, cytotoxicity |
Torres, 2020, International endodontic journal [22] | Total Fill BC, Sealer Plus BC, Bio-C Sealer, AH Plus | chemical-physical properties |
Seo, 2019, Materials [23] | EndoSequence BC Sealer, BioRoot RCS, Endoseal MTA, AH Plus | cytotoxicity and cell migration, mineralizing and osteogenic activity |
Lee, 2019, Materials [24] | EndoSeal MTA, Nano-ceramic Sealer, Wellroot ST, AH Plus, AD Seal | cytotoxicity and cell migration, inflammatory response |
López-García, 2020, Clinical oral investigations [25] | EndoSequence BC Sealer, Ceraseal, Endoseal MTA | cytotoxicity and cell migration, mineralizing and osteogenic activity, ion release |
Gaudin, 2020, Journal of endodontics [26] | BioRoot RCS, ProRoot ES, MTA Fillapex, AH Plus | cytotoxicity and cell migration, inflammatory response |
Sanz, 2020, Clinical oral investigations [27] | Bio-C Sealer ION+, EndoSequence BC Sealer HiFlow, AH Plus | cytotoxicity and cell migration, mineralizing and osteogenic activity, ion release |
Rodríguez-Lozano, 2020, International endodontic journal [28] | EndoSequence BC Sealer HiFlow, EndoSequence BC Sealer, AH Plus | cytotoxicity and cell migration, mineralizing and osteogenic activity |
Alves Silva, 2020, Journal of endodontics [29] | Bio-C Sealer, Sealer Plus BC, AH Plus | inflammatory response, mineralizing and osteogenic activity |
Kim, 2019, Restorative dentistry & endodontics [30] | EndoSeal MTA, AH Plus | Root canal filling efficiency |
Milanovic, 2020, Journal of endodontics [31] | BioRoot RCS, EndoSequence BC Sealer, MTA Fillapex, AH Plus | Root canal filling efficiency |
Kim, 2020, Restorative dentistry & endodontics [32] | Endoseal MTA, AH Plus | Root canal filling efficiency |
Material | Manufacturer | Composition |
---|---|---|
AH Plus | Dentsply DeTrey GmbH, Konstanz, Germany | Bisphenol-A epoxy resin, bisphenol-F epoxy resin, calcium tungstate, zirconium oxide, silica, iron oxide pigments dibenzyldiamine, aminoadamantane, silicone oil |
AD Seal | MetaBiomed, Cheongju, Korea | Base: <20% epoxy resin, NS calcium phosphate, NS zirconium dioxide, NS calcium oxide, NS ethylene glycol, salicylate Catalyst: 2.5–10% N, n-dibenzyl-5-oxanonandiamin-1,9, 2.5–10% amantadine |
TotalFill BC | FKG Dentaire SA, La Chaux-de-Fonds, Switzerland | Zirconium oxide, calcium silicates, calcium phosphate monobasic, calcium hydroxide, filler and thickening agents |
Bio-C Sealer | Angelus, Londrina, PR, Brazil | Calcium silicates, calcium aluminate, calcium oxide, zirconium oxide, iron oxide, silicon dioxide, dispersing agent |
EndoSequence BC Sealer | Brasseler, Savannah, GA, USA | Zirconium oxide, calcium silicates, calcium phosphate monobasic, calcium hydroxide, filler and thickening agents |
EndoSequence BC Sealer HiFlow | Brasseler, Savannah, GA, USA | Zirconium oxide, tricalcium silicate, dicalcium silicate, calcium hydroxide, fillers |
Sealer Plus BC | MK Life, Porto Alegre, RS, Brazil | Zirconium oxide, tricalcium silicate, dicalcium silicate, calcium hydroxide and propylene glycol |
BioRoot RCS | Septodont, Saint Maur-des-Fossés, France | Tricalcium silicate, zirconium oxide (opacifier) and excipients in its powder form, and calcium chloride and excipients as an aqueous liquid |
Endoseal MTA | Maruchi, Wonju, Korea | Calcium silicates, calcium aluminates, calcium aluminoferrite, calcium sulfates, radiopacifier, and thickening agents |
Nano-ceramic Sealer | B&L Biotech, Fairfax, VA, USA | Calcium silicates, zirconium oxide, filler, thickening agent |
Wellroot ST | Vericom, Chuncheon, Korea | Calcium silicate compound, calcium sulfate dehydrate, calcium sodium phosphosilicate, zirconium oxide, titanium oxide, thickening agents |
Ceraseal | Meta Biomed Co., 270, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do, South Korea | Calcium silicates, zirconium oxide, thickening agent |
ProRoot ES | Dentsply Sirona, York, PA | Powder: calcium sulphate, dicalcium silicate, tricalcium silicate, bismuth oxide, and a bit of tricalcium aluminate Liquid (viscous aqueous solution of a water-soluble polymer) |
MTA Fillapex | Angelus, Londrina, PR, Brazil | Paste A: salicylate resin, bismuth trioxide, and fumed silica Paste B: fumed silica, titanium dioxide, mineral trioxide aggregate, and base resin |
Bio-C Sealer ION+ | Angelus, Londrina, PR, Brazil | Calcium silicate, magnesium silicate, polyethylene glycol, zirconium oxide, silicon dioxide nanoparticles, potassium sulphate, calcium sulphate hemihydrate |
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Share and Cite
Dioguardi, M.; Quarta, C.; Sovereto, D.; Troiano, G.; Zhurakivska, K.; Bizzoca, M.E.; Lo Muzio, L.; Lo Russo, L. Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review. Oral 2021, 1, 23-35. https://doi.org/10.3390/oral1010004
Dioguardi M, Quarta C, Sovereto D, Troiano G, Zhurakivska K, Bizzoca ME, Lo Muzio L, Lo Russo L. Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review. Oral. 2021; 1(1):23-35. https://doi.org/10.3390/oral1010004
Chicago/Turabian StyleDioguardi, Mario, Cristian Quarta, Diego Sovereto, Giuseppe Troiano, Khrystyna Zhurakivska, Maria Eleonora Bizzoca, Lorenzo Lo Muzio, and Lucio Lo Russo. 2021. "Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review" Oral 1, no. 1: 23-35. https://doi.org/10.3390/oral1010004