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Abstract

Biodegradable and Transparent PVA/Starch-Based Composite Films for Wound Dressing Applications †

by
Mohammad Mohsen Delavari
* and
Ion Stiharu
Department of Mechanical, Industrial and Aerospace Engineering, Concordia University, Montreal, QC H3G 1M9, Canada
*
Author to whom correspondence should be addressed.
Presented at the 1st International Conference on Micromachines and Applications, 15–30 April 2021; Available online: https://micromachines2021.sciforum.net/.
Published: 14 April 2021
(This article belongs to the Proceedings of The 1st International Conference on Micromachines and Applications)

Abstract

:
Industrial plastic production has the significant benefits of convenience, safety, and low cost. Further to the benefits are added the aesthetic qualities, the mechanical strength and the capability to mix with other materials such as fibers. All these contributed to the rapid expansion of plastics (polystyrene and nylon) in multiple applications and various purposes, such as biomedical materials, packaging, transport, industry, and agriculture. On the other hand, global warming is now one of the most concerning issues for all people. It is considered that replacing some of the conventional materials in various applications such as wound dressings with biodegradable starch-based films is a step forward in addressing environmental issues. Due to mechanical debriding of tissues, traditional dressings like regular cotton gauzes are counterproductive and end up causing painful wound trauma during dressing procedures. The development of transparent wound dressing films enables a moist healing environment with enhanced bacterial impermeability. The performance of polyvinyl alcohol/starch/citric acid (PVA/St/CA) based composite film for wound dressing applications is addressed in this work. Literature recorded fixed composition of PVA (2.5 w/w%), starch (2.5 w/w%), and glycerol (2 w/w%) during 70–80 °C casting temperature. Different citric acid concentrations (0.5 to 2 g) were investigated during the development of composite film solution casting. Prepared samples have been characterized by swelling index, solubility-dependent biodegradability, and tensile strength (TS). The film also exhibits enhanced combinations of the water vapor transmission rate and antibacterial efficiency against the bacterial flora (various bacteria existent in the air). As an extra benefit, such materials are easily degraded in water for up to seven days with a minute footprint. A potential candidate for wound dressing applications has been inferred from the biodegradable PVA/St/CA films with all these useful features.

Supplementary Materials

Institutional Review Board Statement

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Informed Consent Statement

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Data Availability Statement

Not applicable.
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MDPI and ACS Style

Delavari, M.M.; Stiharu, I. Biodegradable and Transparent PVA/Starch-Based Composite Films for Wound Dressing Applications. Eng. Proc. 2021, 4, 31. https://doi.org/10.3390/Micromachines2021-09547

AMA Style

Delavari MM, Stiharu I. Biodegradable and Transparent PVA/Starch-Based Composite Films for Wound Dressing Applications. Engineering Proceedings. 2021; 4(1):31. https://doi.org/10.3390/Micromachines2021-09547

Chicago/Turabian Style

Delavari, Mohammad Mohsen, and Ion Stiharu. 2021. "Biodegradable and Transparent PVA/Starch-Based Composite Films for Wound Dressing Applications" Engineering Proceedings 4, no. 1: 31. https://doi.org/10.3390/Micromachines2021-09547

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