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Volume 17, ECCS 2025
 
 
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Chem. Proc., 2025, ECSOC 2025

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4 pages, 252 KB  
Proceeding Paper
Screening of the Antibacterial Potential of the Biosurfactant Produced by Pseudomonas fluorescens ICCF 392 Against Bacillus sp.
by Roxana Mădălina Stoica
Chem. Proc. 2025, 18(1), 1; https://doi.org/10.3390/ecsoc-29-26915 - 13 Nov 2025
Abstract
Biosurfactants are amphiphilic biocompounds produced by microorganisms, recognized for their surface-active properties and broad biotechnological applicability. The rising concern over antimicrobial resistance and environmental impact of synthetic chemicals has increased the demand for natural and eco-friendly alternatives. Biosurfactants, due to their unique chemical [...] Read more.
Biosurfactants are amphiphilic biocompounds produced by microorganisms, recognized for their surface-active properties and broad biotechnological applicability. The rising concern over antimicrobial resistance and environmental impact of synthetic chemicals has increased the demand for natural and eco-friendly alternatives. Biosurfactants, due to their unique chemical structure and multifunctional properties, have emerged as promising candidates in this regard. These compounds have gained increasing attention due to their biodegradability, low toxicity, and potential to replace synthetic surfactants in various industries. In particular, their antimicrobial properties make them promising agents for applications in food safety, pharmaceuticals, and environmental protection. Pseudomonas fluorescens, a well-known biosurfactant-producing bacterium, has been extensively studied for its capacity to produce rhamnolipids with antimicrobial activity. Therefore, this study aimed to assess the antibacterial potential of the biosurfactant synthesized by Pseudomonas fluorescens ICCF 392 against Bacillus cereus, a Gram-positive bacterium frequently associated with foodborne illnesses. The biosurfactant was obtained through submerged fermentation and partially purified. The antibacterial activity was evaluated using the agar diffusion (cylinder-plate) method, which revealed a clear zone of inhibition measuring 20 mm in diameter. These findings indicate that microbial biosurfactants can serve as effective and sustainable alternatives to conventional antimicrobial agents. Further studies will focus on detailed characterization of the biosurfactant, its spectrum of activity, and potential formulation in various delivery systems. Full article
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8 pages, 1150 KB  
Proceeding Paper
Design, Synthesis, and Catalytic Evaluation of a New Pd-Dipeptide Metal Catalyst in the Stereoselective Formation of C–C Bonds via an Aldol Reaction
by Juan C. Jiménez-Cruz, Ramón Guzmán-Mejía, Pedro Navarro-Santos, Hugo A. García-Gutiérrez, Julio César Ontiveros-Rodríguez, Verónica Cortés-Muñoz and Judit A. Aviña-Verduzco
Chem. Proc. 2025, 18(1), 2; https://doi.org/10.3390/ecsoc-29-26892 (registering DOI) - 13 Nov 2025
Abstract
The mixture of enantiomers in pharmaceuticals can lead to adverse effects, as demonstrated by thalidomide, where one enantiomer exhibited therapeutic properties while the other was teratogenic. Currently, efforts are focused on developing efficient catalysts capable of selectively producing a single stereoisomer, particularly in [...] Read more.
The mixture of enantiomers in pharmaceuticals can lead to adverse effects, as demonstrated by thalidomide, where one enantiomer exhibited therapeutic properties while the other was teratogenic. Currently, efforts are focused on developing efficient catalysts capable of selectively producing a single stereoisomer, particularly in the synthesis of neuropharmaceuticals and NSAIDs. In this context, a new chiral catalyst was synthesized, featuring a palladium core and the dipeptide L-lysine-glycine as a ligand. The catalyst was characterized using various spectroscopic techniques and exhibited enantiomeric excesses of up to 40% in aldol reactions. Additionally, it efficiently promoted Heck cross-coupling reactions, indicating its potential catalytic versatility. Full article
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