Relationship Between Weight Loss and Changes in Oral Function Test Results over 1 Year
Abstract
1. Introduction
2. Materials and Methods
2.1. Tongue Coating Index (TCI)
2.2. Oral Dryness (ODN)
2.3. Occlusal Force (OF)
2.4. Remaining Tooth Number (RTN)
2.5. Oral Diadochokinesis (OD)
2.6. Maximum Tongue Pressure (MTP)
2.7. Masticatory Function (MFN)
2.8. EAT-10
2.9. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| BMI | Body mass index |
| EAT-10 | 10-item Eating Assessment Tool |
| MFN | Masticatory function |
| MTP | Maximum tongue pressure |
| OD | Oral diadochokinesis |
| ODN | Oral dryness |
| OF | Occlusal force |
| RTN | Remaining teeth number |
| SD | Standard deviation |
| TCI | Tongue coating index |
References
- Wallace, J.I.; Schwartz, R.S.; LaCroix, A.Z.; Uhlmann, R.F.; Pearlman, R.A. Involuntary weight loss in older outpatients: Incidence and clinical significance. J. Am. Geriatr. Soc. 1995, 43, 329–337. [Google Scholar] [CrossRef]
- Newman, A.B.; Yanez, D.; Harris, T.; Duxbury, A.; Enright, P.L.; Fried, L.P. Weight change in old age and its association with mortality. J. Am. Geriatr. Soc. 2001, 49, 1309–1318. [Google Scholar] [CrossRef]
- McMinn, J.; Steel, C.; Bowman, A. Investigation and management of unintentional weight loss in older adults. BMJ 2011, 342, d1732. [Google Scholar] [CrossRef] [PubMed]
- Lankisch, P.G.; Gerzmann, M.; Gerzmann, J.-F.; Lehnick, D. Unintentional weight loss: Diagnosis and prognosis. The first prospective follow-up study from a secondary referral centre. J. Intern. Med. 2001, 249, 41–46. [Google Scholar] [CrossRef] [PubMed]
- Metalidis, C.; Knockaert, D.C.; Bobbaers, H.; Vanderschueren, S. Involuntary weight loss: Does a negative baseline evaluation provide adequate reassurance? Eur. J. Intern. Med. 2008, 19, 345–349. [Google Scholar] [CrossRef] [PubMed]
- Gaddey, H.L.; Holder, K. Unintentional weight loss in older adults. Can. Med. Assoc. J. 2014, 183, 935. [Google Scholar] [CrossRef]
- Fried, L.P.; Tangen, C.M.; Walston, J.; Newman, A.B.; Hirsch, C.; Gottdiener, J.; Seeman, T.; Tracy, R.; Kop, W.J.; Burke, G.; et al. Frailty in older adults: Evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 2001, 56, M146–M157. [Google Scholar] [CrossRef]
- Nakamura, M.; Ojima, T.; Nakade, M.; Ohtsuka, R.; Yamamoto, T.; Suzuki, K.; Kondo, K. Poor oral health and diet in relation to weight loss, stable underweight, and obesity in community-dwelling older adults: A cross-sectional study from the JAGES 2010 project. J. Epidemiol. 2016, 26, 322–329. [Google Scholar] [CrossRef]
- Ritchie, C.S.; Joshipura, K.; Silliman, R.A.; Miller, B.; Douglas, C.W. Oral health problems and significant weight loss among community-dwelling older adults. J. Gerontol. A Biol. Sci. Med. Sci. 2000, 55, M366–M371. [Google Scholar] [CrossRef]
- Weyant, R.J.; Newman, A.B.; Kritchevsky, S.B.; Bretz, W.A.; Corby, P.M.; Ren, D.; Weissfeld, L.; Rubin, S.M.; Harris, T. Periodontal disease and weight loss in older adults. J. Am. Geriatr. Soc. 2004, 52, 547–553. [Google Scholar] [CrossRef]
- Kusama, T.; Nakazawa, N.; Kiuchi, S.; Kondo, K.; Osaka, K.; Aida, J. Dental prosthetic treatment reduced the risk of weight loss among older adults with tooth loss. J. Am. Geriatr. Soc. 2021, 69, 2498–2506. [Google Scholar] [CrossRef]
- Minakuchi, S.; Tsuga, K.; Ikebe, K.; Ueda, T.; Tamura, F.; Nagao, K.; Furuya, J.; Matsuo, K.; Yamamoto, K.; Kanazawa, M. Oral hypofunction in the older population: Position paper of the Japanese Society of Gerodontology in 2016. Gerodontology 2018, 35, 317–324. [Google Scholar] [CrossRef] [PubMed]
- Shimizu, T.; Ueda, T.; Sakurai, K. New method for evaluation of tongue-coating status. J. Oral Rehabil. 2007, 34, 442–447. [Google Scholar] [CrossRef] [PubMed]
- Fukushima, Y.; Yoda, T.; Kokabu, S.; Araki, R.; Murata, T.; Kitagawa, Y.; Omura, K.; Toya, S.; Ito, K.; Funayama, S. Evaluation of an oral moisture-checking device for screening dry mouth. Open J. Stomatol. 2013, 3, 440–446. [Google Scholar] [CrossRef]
- Suzuki, T.; Kumagai, H.; Watanabe, T.; Uchida, T.; Nagao, M. Evaluation of complete denture occlusal contacts using pressure-sensitive sheets. Int. J. Prosthodont. 1997, 10, 386–391. [Google Scholar]
- Okamoto, M.; Yoshida, M.; Tsuga, K.; Matsuo, K.; Ikebe, K.; Ueda, T.; Minakuchi, S. Associations of sex, age, and number of remaining teeth with performance on oral hypofunction tests. Gerodontology 2024, 42, 52–60. [Google Scholar] [CrossRef] [PubMed]
- Yamada, A.; Kanazawa, M.; Komagamine, Y.; Minakuchi, S. Association between tongue and lip functions and masticatory performance in young dentate adults. J. Oral Rehabil. 2015, 42, 833–839. [Google Scholar] [CrossRef]
- Yoshikawa, M.; Fukuoka, T.; Mori, T.; Hiraoka, A.; Higa, C.; Kuroki, A.; Takeda, C.; Maruyama, M.; Yoshida, M.; Tsuga, K. Comparison of the Iowa Oral Performance Instrument and JMS tongue pressure measurement device. J. Dent. Sci. 2021, 16, 214–219. [Google Scholar] [CrossRef]
- Uesugi, H.; Shiga, H. Relationship between masticatory performance using a gummy jelly and masticatory movement. J. Prosthodont. Res. 2017, 61, 419–425. [Google Scholar] [CrossRef]
- Belafsky, P.C.; Mouadeb, D.A.; Rees, C.J.; Pryor, J.C.; Postma, G.N.; Allen, J.; Leonard, R.J. Validity and reliability of the Eating Assessment Tool (EAT-10). Ann. Otol. Rhinol. Laryngol. 2008, 117, 919–924. [Google Scholar] [CrossRef]
- Kanie, H.; Yoshida, M.; Yokoi, M.; Okamoto, M.; Sasaki, H.; Ono, K. Relationship between blood test results and oral function tests in individuals undergoing regular physical examinations. J. Oral Rehabil. 2025, 52, 1261–1266. [Google Scholar] [CrossRef]
- Chen, L.; Arai, H.; Assantachai, P.; Akishita, M.; Chew, S.T.H.; Dumlao, L.C.; Duque, G.; Woo, J. Roles of nutrition in muscle health of community-dwelling older adults: Evidence-based expert consensus from Asian Working Group for Sarcopenia. J. Cachexia Sarcopenia Muscle 2022, 13, 1653–1672. [Google Scholar] [CrossRef] [PubMed]
- Sahyoun, N.R.; Krall, E. Low dietary quality among older adults with self-perceived ill-fitting dentures. J. Am. Diet. Assoc. 2003, 103, 1494–1499. [Google Scholar] [CrossRef] [PubMed]
- Inomata, C.; Ikebe, K.; Kagawa, R.; Okubo, H.; Sasaki, S.; Okada, T.; Takeshita, H.; Tada, S.; Matsuda, K.; Kurushima, Y. Significance of occlusal force for dietary fibre and vitamin intakes in independently living 70-year-old Japanese: From SONIC study. J. Dent. 2014, 42, 556–564. [Google Scholar] [CrossRef] [PubMed]
- Hatanaka, Y.; Furuya, J.; Sato, Y.; Uchida, Y.; Shichita, T.; Kitagawa, N.; Osawa, T. Associations between oral hypofunction tests, age, and sex. Int. J. Environ. Res. Public Health 2021, 18, 10256. [Google Scholar] [CrossRef]
- Yoshida, M.; Hiraoka, A.; Takeda, C.; Mori, T.; Maruyama, M.; Yoshikawa, M.; Tsuga, K. Oral hypofunction and its relation to frailty and sarcopenia in community-dwelling older people. Gerodontology 2022, 39, 26–32. [Google Scholar] [CrossRef]
| 2023 | 2024 | Change Rate (%) | p-Value | ||||
|---|---|---|---|---|---|---|---|
| Δ = (2024 − 2023)/2023 × 100 | 2023 vs. 2024 | ||||||
| Mean | SD | Mean | SD | Mean | SD | ||
| Body weight (kg) | 65.7 | 12.4 | 65.7 | 11.9 | 0.2 | 3.4 | 0.525 |
| BMI (kg/m2) | 24.0 | 3.3 | 24.0 | 3.1 | 0.1 | 3.6 | 0.887 |
| TCI (%) | 1.0 | 4.7 | 2.7 | 7.1 | – | – | 0.066 |
| ODN (unit) | 27.9 | 1.2 | 28.2 | 1.6 | 1.2 | 6.7 | 0.090 |
| OF (N) | 1023.0 | 512.4 | 1045.8 | 573.2 | 9.6 | 49.6 | 0.952 |
| RTN (teeth) | 25.4 | 5.5 | 25.3 | 5.6 | −0.3 | 5.0 | 0.137 |
| OD/pa/(/s) | 6.7 | 0.6 | 6.7 | 0.7 | 0.4 | 7.9 | 0.514 |
| OD/ta/(/s) | 6.7 | 0.8 | 6.7 | 0.8 | 0.6 | 7.1 | 0.722 |
| OD/ka/(/s) | 6.1 | 0.9 | 6.2 | 0.8 | 1.5 | 12.7 | 0.900 |
| MTP (kPa) | 37.5 | 8.3 | 37.2 | 8.3 | −0.2 | 11.9 | 0.742 |
| MFN (g/mL) | 232.2 | 69.6 | 234.2 | 68.8 | 6.5 | 38.6 | 0.647 |
| EAT-10 (point) | 0.3 | 1.1 | 0.3 | 1.5 | – | – | 0.750 |
| ΔBody Weight (%) | ||
|---|---|---|
| Spearman’s ρ | Correlation Coefficient | p-Value |
| ΔODN (%) | −0.092 | 0.354 |
| ΔOF (%) | 0.239 * | 0.015 * |
| ΔOD/pa/(%) | −0.049 | 0.625 |
| ΔOD/ta/(%) | 0.02 | 0.842 |
| ΔOD/ka/(%) | −0.068 | 0.49 |
| ΔMTP (%) | 0.116 | 0.242 |
| ΔMFN (%) | 0.200 * | 0.043 * |
| Body Weight Change | p-Value | ||||
|---|---|---|---|---|---|
| ≥5% | <5% | χ2 Test | |||
| M = 5, F = 3 | M = 65, F = 31 | 0.714 | |||
| Mean | SD | Mean | SD | Mann–Whitney U Test | |
| Age (y) | 64.6 | 10.3 | 66.0 | 10.8 | 0.674 |
| ΔODN (%) | −0.4 | 6.1 | 1.4 | 6.7 | 0.468 |
| ΔOF (%) | −17.7 | 11.9 | 11.9 | 50.9 | 0.017 * |
| ΔOD/pa/(%) | 4.0 | 7.0 | 0.1 | 8.0 | 0.167 |
| ΔOD/ta/(%) | −0.3 | 7.0 | 0.7 | 7.1 | 0.976 |
| ΔOD/ka/(%) | −0.1 | 10.1 | 1.6 | 13.0 | 0.801 |
| ΔMTP (%) | 0.1 | 15.4 | −0.2 | 11.7 | 0.981 |
| ΔMFN (%) | −7.9 | 15.9 | 7.7 | 39.7 | 0.200 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Igashira, R.; Yokoi, M.; Okamoto, M.; Sasaki, H.; Yoshida, M. Relationship Between Weight Loss and Changes in Oral Function Test Results over 1 Year. Obesities 2026, 6, 8. https://doi.org/10.3390/obesities6010008
Igashira R, Yokoi M, Okamoto M, Sasaki H, Yoshida M. Relationship Between Weight Loss and Changes in Oral Function Test Results over 1 Year. Obesities. 2026; 6(1):8. https://doi.org/10.3390/obesities6010008
Chicago/Turabian StyleIgashira, Ryoko, Miyuki Yokoi, Mieko Okamoto, Hitomi Sasaki, and Mitsuyoshi Yoshida. 2026. "Relationship Between Weight Loss and Changes in Oral Function Test Results over 1 Year" Obesities 6, no. 1: 8. https://doi.org/10.3390/obesities6010008
APA StyleIgashira, R., Yokoi, M., Okamoto, M., Sasaki, H., & Yoshida, M. (2026). Relationship Between Weight Loss and Changes in Oral Function Test Results over 1 Year. Obesities, 6(1), 8. https://doi.org/10.3390/obesities6010008

