Uterine Smooth Muscle Tumor of Uncertain Malignant Potential: A Retrospective, Monocentric Cohort Study
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Patient | Age (Years) | Symptoms | Preoperative Imaging Features | Surgical Management | Histological Features | Medical Treatment | Follow-Up | Relapse |
---|---|---|---|---|---|---|---|---|
1 | 71 | Menometrorrhagia causing fatigue, pelvic pain, bloating, and constipation | Solitary 4 cm round, hypoechoic intramural lesion with a clear whorled pattern in the posterior uterine wall | LPT hysterectomy | Endometrial cancer (pT1 pN0 G2 FIGO Stage IA) and STUMP | No | Normal | No |
2 | 32 | Menometrorrhagia causing weakness, pelvic pain, menstrual cramps, and lower abdominal fullness | Isolated 8 cm isoechoic, intramural mass with a whorled appearance in the anterior uterine wall | LPT myomectomy | Moderate atypia, <10 MFs/10 HPFs, no CTCN | No | Normal | No |
3 | 57 | Menometrorrhagia causing fatigue, pelvic pain, and painful bowel movements | Single, sizable 13 cm intramural growth, appearing as a round, well-circumscribed hypoechoic mass in the uterine fundus | LPT hysterectomy | <10 MFs/10 HPFs, CTCN, spindle cells = 30% | No | Clinically stable | Well-differentiated leiomyosarcoma at the left pararectal fossa and the right thigh 36 months after surgery |
4 | 36 | Menometrorrhagia with prolonged periods, pelvic pain, lower back pain, and bloating | Solitary 6 cm hypoechoic intramural lesion with a distinctive whorled texture in the posterior uterine wall | LPT myomectomy | Atypia, <10 MFs/10 HPFs, no CTCN | No | Normal | No |
5 | 50 | Menometrorrhagia with irregular menstrual cycle, pelvic pain intensified during periods, and dysuria | Lone, round, 4 cm hypoechoic intramural mass, displaying a characteristic whorled pattern in the anterior uterine wall | LPT hysterectomy | Focal atypia, <10 MFs/10 HPFs | No | Normal | No |
6 | 50 | Menometrorrhagia leading to anemia, pelvic pain, sensation of pelvic heaviness, and discomfort during intercourse | Single, well-defined 2 cm intramural lesion of hypoechoic texture with a whorled pattern in the right lateral uterine wall | LPS hysterectomy | Moderate atypia, <10 MFs/10 HPFs, no CTCN, Ki-67 = 5% | No | Normal | No |
7 | 28 | Menometrorrhagia causing tiredness and lightheadedness, with pelvic pain, menstrual cramps, and dysuria | Solitary 4.5 cm hypoechoic intramural mass with a clear whorled appearance in the left lateral uterine wall | LPT myomectomy | Moderate atypia, low mitotic count | No | Normal | No |
8 | 33 | Menometrorrhagia leading to anemia, pelvic pain, and difficulties emptying the bladder | Lone intramural growth of 7 cm, appearing as a well-circumscribed, hypoechoic mass with a typical whorled pattern in the anterior uterine wall | LPT myomectomy | GnRH agonists for 6 months after surgery | Myometrial lesion 10 months after surgery | Second surgery refused by the patient | |
9 | 53 | Menometrorrhagia leading to anemia and lower back discomfort | Solitary, large 10 cm intramural tumor, presenting as a hypoechoic mass with a distinct whorled texture in the uterine fundus | LPT hysterectomy | <5 MFs/10 HPFs | No | Normal | No |
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Ettore, C.; Incognito, G.G.; Gulino, F.A.; Russo, E.; Cannone, F.; Ettore, G. Uterine Smooth Muscle Tumor of Uncertain Malignant Potential: A Retrospective, Monocentric Cohort Study. Surgeries 2023, 4, 412-419. https://doi.org/10.3390/surgeries4030041
Ettore C, Incognito GG, Gulino FA, Russo E, Cannone F, Ettore G. Uterine Smooth Muscle Tumor of Uncertain Malignant Potential: A Retrospective, Monocentric Cohort Study. Surgeries. 2023; 4(3):412-419. https://doi.org/10.3390/surgeries4030041
Chicago/Turabian StyleEttore, Carla, Giosuè Giordano Incognito, Ferdinando Antonio Gulino, Emanuele Russo, Francesco Cannone, and Giuseppe Ettore. 2023. "Uterine Smooth Muscle Tumor of Uncertain Malignant Potential: A Retrospective, Monocentric Cohort Study" Surgeries 4, no. 3: 412-419. https://doi.org/10.3390/surgeries4030041
APA StyleEttore, C., Incognito, G. G., Gulino, F. A., Russo, E., Cannone, F., & Ettore, G. (2023). Uterine Smooth Muscle Tumor of Uncertain Malignant Potential: A Retrospective, Monocentric Cohort Study. Surgeries, 4(3), 412-419. https://doi.org/10.3390/surgeries4030041