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Chanwuyi Lifestyle Medicine Program Alleviates Immunological Deviation and Improves Behaviors in Autism

1
Neuropsychology Laboratory, Department of Psychology, The Chinese University of Hong Kong, Hong Kong, China
2
Research Center for Neuropsychological Well-Being, The Chinese University of Hong Kong, Hong Kong, China
3
Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China
4
Department of Chemical Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
5
Department of Social Work, The Chinese University of Hong Kong, Hong Kong, China
*
Author to whom correspondence should be addressed.
Academic Editor: Asher Ornoy
NeuroSci 2021, 2(2), 207-223; https://doi.org/10.3390/neurosci2020015
Received: 8 April 2021 / Revised: 28 May 2021 / Accepted: 3 June 2021 / Published: 7 June 2021
Given the association between deviated inflammatory chemokines, the pathogenesis of autism spectrum disorders (ASD), and our previous findings of the Chanwuyi Lifestyle Medicine Program regarding improved cognitive and behavioral problems in ASD, the present study aims to explore if this intervention can alter pro-inflammatory chemokines concentration. Thirty-two boys with ASD were assigned to the experimental group receiving the Chanwuyi Lifestyle Medicine Program for 7 months or the control group without a change in their lifestyle. The experimental group, but not the control group, demonstrated significantly reduced CCL2 and CXCL8, a trend of reduction in CCL5, and elevation of CXCL9. The experimental group also demonstrated significantly reduced social communication problems, repetitive/stereotypic behaviors, and hyperactive behaviors. The present findings support the potential efficacy and applicability of the Chanwuyi Lifestyle Medicine Program for reducing both behavioral problems and immunological dysfunction in ASD. Further studies are warranted to verify its treatment effect and its association with brain functions. View Full-Text
Keywords: autism spectrum disorders; intervention; chemokine; pro-inflammatory; behavioral problems autism spectrum disorders; intervention; chemokine; pro-inflammatory; behavioral problems
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MDPI and ACS Style

Chan, A.S.; Han, Y.M.Y.; Sze, S.L.; Wong, C.-k.; Chu, I.M.T.; Cheung, M.-c. Chanwuyi Lifestyle Medicine Program Alleviates Immunological Deviation and Improves Behaviors in Autism. NeuroSci 2021, 2, 207-223. https://doi.org/10.3390/neurosci2020015

AMA Style

Chan AS, Han YMY, Sze SL, Wong C-k, Chu IMT, Cheung M-c. Chanwuyi Lifestyle Medicine Program Alleviates Immunological Deviation and Improves Behaviors in Autism. NeuroSci. 2021; 2(2):207-223. https://doi.org/10.3390/neurosci2020015

Chicago/Turabian Style

Chan, Agnes S., Yvonne M.Y. Han, Sophia L. Sze, Chun-kwok Wong, Ida M.T. Chu, and Mei-chun Cheung. 2021. "Chanwuyi Lifestyle Medicine Program Alleviates Immunological Deviation and Improves Behaviors in Autism" NeuroSci 2, no. 2: 207-223. https://doi.org/10.3390/neurosci2020015

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