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Prescribing Warfarin to a Patient with Oesophageal Varices—A Case Report and Review of the Literature

1
General Surgical Department, Sheffield Teaching Hospitals NHS Foundation Trust, Herries Road, Sheffield S5 7AU, UK
2
Cancer Biomarkers Group, Swansea University, Singleton Park, Swansea SA2 8PP, UK
*
Author to whom correspondence should be addressed.
Reports 2018, 1(3), 18; https://doi.org/10.3390/reports1030018
Received: 29 August 2018 / Revised: 19 September 2018 / Accepted: 25 September 2018 / Published: 28 September 2018
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PDF [541 KB, uploaded 28 September 2018]
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Abstract

We describe the case of a 42-year old man who presented with melaena. He was found to have bleeding varices during endoscopic investigation. Subsequent investigation revealed the aetiology to be a portal vein thrombosis (PVT) due to an underlying pro-coagulable state (Factor V Leiden). He was managed with cautious anticoagulation but suffered a life-threatening upper gastrointestinal bleed that was not amenable to endoscopic treatment or transjugular intrahepatic portosystemic shunting (TIPS). As such, the only therapeutic option involved the pursuit of surgical shunt operations. We review the literature regarding this atypical cause of GI-bleeding and discuss medical and surgical considerations for the management of such patients. View Full-Text
Keywords: Factor V Leiden; Gastrointestinal Hemorrhage; portal vein; portosystemic shunt; anticoagulation Factor V Leiden; Gastrointestinal Hemorrhage; portal vein; portosystemic shunt; anticoagulation
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George, J.; Haboubi, H.N. Prescribing Warfarin to a Patient with Oesophageal Varices—A Case Report and Review of the Literature. Reports 2018, 1, 18.

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