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Extended Abstract

Atypical Gingival Swelling Unrelated to Plaque and Tartar: Diagnostic Difficulty and Conservative Treatment †

1
RDH, Freelancer in Brindisi, 72100 Brindisi, Italy
2
DDS, Private Dental Practice, 72013 Ceglie Messapica, Italy
3
RDH, Freelancer in Canosa di Puglia, 76012 Canosa di Puglia, Italy
4
DDS, Department of Radiology, San Paolo Dental Bulding, University of Milan, 20121 Milan, Italy
5
DDS, Private Dental Practice, 09121 Cagliari, Italy
*
Author to whom correspondence should be addressed.
Presented at the XV National and III International Congress of the Italian Society of Oral Pathology and Medicine (SIPMO), Bari, Italy, 17–19 October 2019.
Proceedings 2019, 35(1), 64; https://doi.org/10.3390/proceedings2019035064
Published: 12 December 2019

1. Introduction

In recent years, works have shown that probiotics have beneficial localized effects. Probiotic treatment is effective against diseases and infections of the skin and mucous membranes [1]. Several studies on the probiotic Lactobacillus Reuteri (L. Reuteri) have demonstrated anti-inflammatories and antimicrobials effects [2].

2. Materials and Methods

A 48-year-old female patient with non-plaque and tartar gingival papilla swelling between the upper incisors 1.1–1.2, went to our observation (Figure 1). She takes drugs for hypertension and vitamin D supplement, suffers from periodontal diseases in a good state of maintenance and was subjected to professional oral hygiene sessions every 4 months. It was decided to perform a biopsy, scheduled 2 weeks later. To restore the oral probiotic microbiota L. Reuteri have been suggested. Tablets of Lactobacillus Reuteri DSM 17938 ATCC PTA 5289 have been prescribed as home therapy twice a day, for two weeks, dissolving them slowly in the mouth after careful oral hygiene, taking care to rub the tablet with the tongue against the swollen papilla. At the check the gum appeared during the normalization phase, so the treatment was prolonged for another two weeks, and the biopsy has been postponed (Figure 2).

3. Results

4 weeks of follow-up were carried out. The gingival papilla is completely healed after treatment with L. Reuteri.

4. Discussion and Conclusions

Oral treatment with tablets containing the probiotic strain of L. Reuteri induces in most patients a significant reduction in the proinflammatory cytokine response and an improvement in clinical parameters [3]. L. Reuteri is known for its secretion of 2 bacteriocins, reuterine and reutericiclina, which inhibit the growth of a wide variety of pathogens; it also has a strong ability to adhere to host tissues with localized anti-inflammatory and antimicrobial effects [2]. Probiotics present a new ray of hope in periodontal therapy with a proven track record of safety and efficacy [2,3]. The use of topical probiotics in the treatment of gingival hypertrophy could be considered a valid alternative to conventional treatments. Further studies must be performed to confirm this starting result.

Conflicts of Interest

The authors declare no conflict of interest.

References

  1. Friedrich, A.D.; Paz, M.L.; Leoni, J.; González Maglio, D.H. Message in a Bottle: Dialog between Intestine and Skin Modulated by Probiotics. Int. J. Mol. Sci. 2017, 18, 1067. [Google Scholar] [CrossRef] [PubMed]
  2. Laleman, I.; Pauwels, M.; Quirynen, M.; Teughels, W. A dual strain Lactobacilli reuteri probiotic improves the treatment of residual pockets: a randomized controlled-clinical trial. J. Clin. Periodontol. 2019. [Google Scholar] [CrossRef] [PubMed]
  3. Penala, S.; Kalakonda, B.; Pathakota, K.R.; Jayakumar, A.; Koppolu, P.; Lakshmi, B.V.; Pandey, R.; Mishra, A. Efficacy of local use of probiotics as an adjunct to scaling and root planing in chronic periodontitis and halitosis: A randomized controlled trial. J. Res. Pharm. Pract. 2016, 5, 86–93. [Google Scholar] [CrossRef] [PubMed]
Figure 1. Patient before using probiotics L. Reuteri DSM 17938 ATCC PTA 5289.
Figure 1. Patient before using probiotics L. Reuteri DSM 17938 ATCC PTA 5289.
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Figure 2. Patient 4 weeks after therapy with L. Reuteri DSM 17938 ATCC PTA 5289.
Figure 2. Patient 4 weeks after therapy with L. Reuteri DSM 17938 ATCC PTA 5289.
Proceedings 35 00064 g002
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MDPI and ACS Style

Mosaico, G.; Chirulli, A.; Sinesi, A.; Viganò, L.; Casu, C. Atypical Gingival Swelling Unrelated to Plaque and Tartar: Diagnostic Difficulty and Conservative Treatment. Proceedings 2019, 35, 64. https://doi.org/10.3390/proceedings2019035064

AMA Style

Mosaico G, Chirulli A, Sinesi A, Viganò L, Casu C. Atypical Gingival Swelling Unrelated to Plaque and Tartar: Diagnostic Difficulty and Conservative Treatment. Proceedings. 2019; 35(1):64. https://doi.org/10.3390/proceedings2019035064

Chicago/Turabian Style

Mosaico, Giovanna, Alessio Chirulli, Antonia Sinesi, Luca Viganò, and Cinzia Casu. 2019. "Atypical Gingival Swelling Unrelated to Plaque and Tartar: Diagnostic Difficulty and Conservative Treatment" Proceedings 35, no. 1: 64. https://doi.org/10.3390/proceedings2019035064

APA Style

Mosaico, G., Chirulli, A., Sinesi, A., Viganò, L., & Casu, C. (2019). Atypical Gingival Swelling Unrelated to Plaque and Tartar: Diagnostic Difficulty and Conservative Treatment. Proceedings, 35(1), 64. https://doi.org/10.3390/proceedings2019035064

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