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Abstract

Revisiting Subperiosteal Implants: A Narrative Review of the Contemporary Literature †

by
Robert-Ramzi Azar
1,
Edward-Ronald Azar
2,
Andreea-Violeta Ardelean
3,
Alexandra-Denisa Stoian
1,4,
Georgiana Boici
1,4,
Cosmin Sinescu
2,3 and
Meda-Lavinia Negruțiu
2,3,*
1
Doctoral School, Faculty of Dental Medicine, “Victor Babeş” University of Medicine and Pharmacy Timişoara, 2 E. Murgu Sq., 300041 Timişoara, Romania
2
Research Center in Dental Medicine Using Conventional and Alternative Technologies, “Victor Babeş” University of Medicine and Pharmacy Timişoara, 2 E. Murgu Sq., 300041 Timişoara, Romania
3
Department of Prostheses Technology and Dental Materials, Faculty of Dental Medicine, University of Medicine and Pharmacy “Victor Babeş” Timișoara, 2 E. Murgu Sq., 300041 Timişoara, Romania
4
Department of Technology of Materials and Devices in Dental Medicine, Faculty of Dental Medicine, “Victor Babes” University of Medicine and Pharmacy Timisoara, 2 E. Murgu Sq., 300041 Timişoara, Romania
*
Author to whom correspondence should be addressed.
Presented at the International Conference on Interdisciplinary Approaches and Emerging Trends in Pharmaceutical Doctoral Research: Innovation and Integration, Timisoara, Romania, 7–9 July 2025.
Proceedings 2025, 127(1), 29; https://doi.org/10.3390/proceedings2025127029
Published: 20 October 2025
Subperiosteal implants, once a historical footnote in implant dentistry, are experiencing a revival in the digital era. This study provides an overview of modern CAD/CAM-designed subperiosteal implants for patients with severe jaw atrophy. Severe atrophic jaws often cannot retain conventional screw implants without extensive bone grafting. Subperiosteal implants offer a graft-less solution by resting a custom-fitted framework on the bone surface under the periosteum [1,2].
Our review of recent literature (2019–2025) shows that digitally fabricated subperiosteal implants achieve high short-term success rates. In studies totaling over 200 patients, the implant survival within ~2 years exceeded 95–98% [1,2,3,4,5]. Avoiding bone graft surgery is a key advantage, particularly for elderly or medically compromised patients.
The main concern with subperiosteal implants remains soft-tissue health. Unlike an internal implant post, a subperiosteal frame spans a large area under the gums. About one-quarter of cases in short-term studies experienced some gum dehiscence or exposure of the metal framework. These exposures were usually small and manageable, but they signal that the gum integration is not always ideal. Infection around the implant occurred in a smaller percentage of patients (~5%) [4,5], often linked to those exposure sites. Long-term data (5–6 years) are only beginning to emerge. One 6-year follow-up reported that while almost all implants were still physically present (high survival), only 25% of cases remained completely free of complications over that time. This indicates that gradual bone resorption or tissue thinning can lead to late issues, even if the implant initially succeeds. Therefore, long-term maintenance and perhaps periodic soft tissue grafting might be necessary to sustain these implants over a decade or more [1,3].
Compared to zygomatic implants, subperiosteal implants had similar 5-year survival rates (97.1% vs. 96.3%), with complications limited to the soft tissue as the sinus was avoided entirely (12% sinus-related complications in zygomatic implants). Patient satisfaction improved in terms of function and esthetics [4].
In conclusion, modern subperiosteal implants show great promise as a custom-tailored remedy for extreme jaw atrophy. They achieve functional rehabilitation with high short-term success, rivaling alternative techniques. However, careful patient selection and diligent follow-up are essential, given the soft-tissue-related challenges. As technology and techniques improve, subperiosteal implants could firmly re-establish themselves as a valuable option in implant dentistry, offering hope to patients who were once deemed untreatable with fixed restorations.

Author Contributions

Conceptualization, R.-R.A., E.-R.A., A.-V.A., C.S. and M.-L.N.; methodology, R.-R.A., C.S. and M.-L.N.; investigation, R.-R.A., E.-R.A., A.-D.S. and G.B.; data and statistical analysis, R.-R.A. and E.-R.A.; supervision and project administration: C.S. and M.-L.N.; writing—original draft: R.-R.A., E.-R.A. and A.-V.A.; writing—review and editing: R.-R.A. and E.-R.A.; All authors have read and agreed to the published version of the manuscript.

Funding

The APC was funded by the Doctoral School, Faculty of Dental Medicine, “Victor Babeş” University of Medicine and Pharmacy Timișoara.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

Data is contained within the article.

Conflicts of Interest

The authors declare no conflict of interest.

References

  1. Darwish, S.A.; El-Mohandes, W.A.; Abd Rabbo, B.E. Clinical and Radiographic Assessment of Milled Versus 3D-Printed Patient-Specific Subperiosteal Implants for Atrophic Mandibular Ridges: A Randomized Clinical Trial. Cureus 2025, 17, e80326. [Google Scholar] [CrossRef] [PubMed]
  2. Anitua, E.; Eguia, A.; Staudigl, C.; Alkhraisat, M.H. Clinical performance of additively manufactured subperiosteal implants: A systematic review. Int. J. Implant. Dent. 2024, 10, 4. [Google Scholar] [CrossRef] [PubMed]
  3. Gasparini, G.; Todaro, M.; De Angelis, P.; Boniello, R.; Saponaro, G.; Rella, E.; Foresta, E.; Hreniuc, H.V.; Azzuni, F.; Pashaj, E.; et al. Clinical Outcomes of CAD-CAM Subperiosteal Implants for the Rehabilitation of Atrophic Jaws. Dent. J. 2024, 12, 241. [Google Scholar] [CrossRef] [PubMed]
  4. Zielinski, R.; Okulski, J.; Piechaczek, M.; Łoś, J.; Sowiński, J.; Sadowska-Sowińska, M.; Kołkowska, A.; Simka, W.; Kozakiewicz, M. Five-Year Comparative Study of Zygomatic and Subperiosteal Implants: Clinical Outcomes, Complications, and Treatment Strategies for Severe Maxillary Atrophy. J. Clin. Med. 2025, 14, 661. [Google Scholar] [CrossRef] [PubMed]
  5. Nedelcu, L.; Sirbu, I.; Sirbu, V.D.; Custura, A.M.; Radu, A.; Nastasie, V. Custom-made 3D printed subperiosteal implant for restoration of severe atrophic jaw: A case report. Clin. Case Rep. 2024, 12, e9515. [Google Scholar] [CrossRef] [PubMed]
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Share and Cite

MDPI and ACS Style

Azar, R.-R.; Azar, E.-R.; Ardelean, A.-V.; Stoian, A.-D.; Boici, G.; Sinescu, C.; Negruțiu, M.-L. Revisiting Subperiosteal Implants: A Narrative Review of the Contemporary Literature. Proceedings 2025, 127, 29. https://doi.org/10.3390/proceedings2025127029

AMA Style

Azar R-R, Azar E-R, Ardelean A-V, Stoian A-D, Boici G, Sinescu C, Negruțiu M-L. Revisiting Subperiosteal Implants: A Narrative Review of the Contemporary Literature. Proceedings. 2025; 127(1):29. https://doi.org/10.3390/proceedings2025127029

Chicago/Turabian Style

Azar, Robert-Ramzi, Edward-Ronald Azar, Andreea-Violeta Ardelean, Alexandra-Denisa Stoian, Georgiana Boici, Cosmin Sinescu, and Meda-Lavinia Negruțiu. 2025. "Revisiting Subperiosteal Implants: A Narrative Review of the Contemporary Literature" Proceedings 127, no. 1: 29. https://doi.org/10.3390/proceedings2025127029

APA Style

Azar, R.-R., Azar, E.-R., Ardelean, A.-V., Stoian, A.-D., Boici, G., Sinescu, C., & Negruțiu, M.-L. (2025). Revisiting Subperiosteal Implants: A Narrative Review of the Contemporary Literature. Proceedings, 127(1), 29. https://doi.org/10.3390/proceedings2025127029

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