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Abstract

Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase †

by
Caterina Pont
1,
Nelson Alencar
2,3,
Irene Sola
1,
María Linares
4,
Luca Di Palma
1,
Carla Barbaraci
1,
Cristina Sampedro
1,
Jordi Juárez-Jiménez
2,
Paloma Abad
4,5,
Susana Pérez-Benavente
5,
Jerónimo Lameira
3,
José M. Bautista
4,5,
F. Javier Luque
2 and
Diego Muñoz-Torrero
1,*
1
Laboratory of Pharmaceutical Chemistry (CSIC Associated Unit), Faculty of Pharmacy and Food Sciences and Institute of Biomedicine (IBUB), University of Barcelona (UB), Av. Joan XXIII 27-31, E-08028 Barcelona, Spain
2
Department of Nutrition, Food Science and Gastronomy, Faculty of Pharmacy and Food Sciences, and IBUB, University of Barcelona, Av. Prat de la Riba 171, E-08921 Santa Coloma de Gramenet, Spain
3
Laboratório de Planejamento e Desenvolvimento de Fármacos-LPDF, Instituto de Ciências Exatas e Naturais-ICEN, Universidade Federal do Pará—UFPA, Av. Augusto Correa, Nº 1-Bairro: Guamá, Cep: 66.075-900 Belém-Pará, Brazil
4
Research Institute Hospital 12 de Octubre, Avda. de Cordoba s/n, 28041 Madrid, Spain
5
Department of Biochemistry and Molecular Biology, Universidad Complutense de Madrid, Facultad de Veterinaria, Ciudad Universitaria, 28040-Madrid, Spain
*
Author to whom correspondence should be addressed.
†
Presented at the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain, 8 September 2017.
Proceedings 2017, 1(6), 665; https://doi.org/10.3390/proceedings1060665
Published: 18 October 2017
(This article belongs to the Proceedings of Proceedings of the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain)
Versions Notes

Excerpt

Note: In lieu of an abstract, this is an excerpt from the first page.

There currently exists a dire need for safe and inexpensive new antimalarial drugs, which are effective against multiple life cycle stages of Plasmodium falciparum, and act through mechanisms that differ from those of the available drugs to prevent drug resistance. [...]

Share and Cite

MDPI and ACS Style

Pont, C.; Alencar, N.; Sola, I.; Linares, M.; Palma, L.D.; Barbaraci, C.; Sampedro, C.; Juárez-Jiménez, J.; Abad, P.; Pérez-Benavente, S.; et al. Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. Proceedings 2017, 1, 665. https://doi.org/10.3390/proceedings1060665

AMA Style

Pont C, Alencar N, Sola I, Linares M, Palma LD, Barbaraci C, Sampedro C, Juárez-Jiménez J, Abad P, Pérez-Benavente S, et al. Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. Proceedings. 2017; 1(6):665. https://doi.org/10.3390/proceedings1060665

Chicago/Turabian Style

Pont, Caterina, Nelson Alencar, Irene Sola, María Linares, Luca Di Palma, Carla Barbaraci, Cristina Sampedro, Jordi Juárez-Jiménez, Paloma Abad, Susana Pérez-Benavente, and et al. 2017. "Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase" Proceedings 1, no. 6: 665. https://doi.org/10.3390/proceedings1060665

APA Style

Pont, C., Alencar, N., Sola, I., Linares, M., Palma, L. D., Barbaraci, C., Sampedro, C., Juárez-Jiménez, J., Abad, P., Pérez-Benavente, S., Lameira, J., Bautista, J. M., Luque, F. J., & Muñoz-Torrero, D. (2017). Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. Proceedings, 1(6), 665. https://doi.org/10.3390/proceedings1060665

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