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Proceedings 2017, 1(4), 521;

Highly Sensitive Electrochemical Glutamate Microsensors for Food Analysis

Laboratory for Sensors, IMTEK—Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany
Presented at the Eurosensors 2017 Conference, Paris, France, 3–6 September 2017.
Author to whom correspondence should be addressed.
Published: 11 August 2017
(This article belongs to the Proceedings of Eurosensors 2017)
PDF [535 KB, uploaded 6 September 2017]


Electrochemical microsensors are ideal to measure substances with low concentration in complex environments. The primary excitatory neurotransmitter l-glutamate is present in many foods as a distinctive flavour (enhancer) with a wide concentration range. In comparison to other methods, electrochemical sensors allow the rapid, precise, cost-effective, online measurement without any sample treatment. We developed a disposable electrochemical microsensor platform with multiple integrated, highly sensitive (detection limit <150 nM) and selective enzyme-based glutamate biosensors. We showed both the precise determination of glutamate levels in processed foods with high glutamate content (15–40 mM), e.g., broth, and in foods with low natural concentrations such as different types of cow’s milk (~250 μM). Hereby, we successfully demonstrated the capabilities of electrochemical biosensors in food monitoring, analysis and quality control.
Keywords: monosodium glutamate; neurotransmitter; biosensor; enzyme; food; milk monosodium glutamate; neurotransmitter; biosensor; enzyme; food; milk
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Weltin, A.; Kieninger, J.; Urban, G.A. Highly Sensitive Electrochemical Glutamate Microsensors for Food Analysis. Proceedings 2017, 1, 521.

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