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Cytotoxic Activity of Endemic Astragalus argaeus Boiss. from Turkey †

Biology Department, Science Faculty, Erciyes University, Kayseri 38039, Turkey
Graduate School Natural Applied Science, Erciyes University, Kayseri 38039, Turkey
Author to whom correspondence should be addressed.
Presented at the 2nd International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 8–11 November 2017.
Proceedings 2017, 1(10), 1040;
Published: 10 November 2017


Astragalus L. is the largest genus in the family Leguminosae with over 3000 species and is represented in Turkey by 445 species, of which 224 are endemic. Several Astragalus species have many biological properties such as hepatoprotective, immunostimulant, antiviral, anti-aging, antitumor, antioxidant, antimicrobial, antimalarial, antileshmanial, antiperspirant, anti-inflammatory, diuretic and tonic. The aim of this research was the investigation of the cytotoxic activities of extracts obtained from underground and aerial parts of Astragalus argaeus Boiss. on a human breast cancer cell line (MCF-7). The cytotoxic effects of extracts on MCF-7 (human breast cancer cell lines) and fibroblast cells during 24 and 48 h were determined by 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphynyl tetrazolium bromide (MTT) assay. The extracts showed weak cytotoxic activity on MCF-7 during 24 h. To the best of our knowledge, this study is the first report on cytotoxic activity of A. argaeus.


This work was supported by the Research Fund of the University of Erciyes. Project number is FYL-2014-5072.
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MDPI and ACS Style

Albayrak, S.; Kaya, O. Cytotoxic Activity of Endemic Astragalus argaeus Boiss. from Turkey. Proceedings 2017, 1, 1040.

AMA Style

Albayrak S, Kaya O. Cytotoxic Activity of Endemic Astragalus argaeus Boiss. from Turkey. Proceedings. 2017; 1(10):1040.

Chicago/Turabian Style

Albayrak, Sevil, and Onur Kaya. 2017. "Cytotoxic Activity of Endemic Astragalus argaeus Boiss. from Turkey" Proceedings 1, no. 10: 1040.

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