Q Fever in the First Trimester: A Case Report from Northern Rural New South Wales
Abstract
:1. Introduction
2. Case Discussion
3. Discussion
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
Permission
Appendix A
IFA Serology | 9 Weeks Gestation | 36 Weeks Gestation | 3 Months Post-Partum | Reference |
---|---|---|---|---|
Phase II IgM | >400 | 50 | <25 | <25 |
Phase II IgG | 3200 | 1600 | 100 | <25 |
Phase I IgG | <100 | 800 | 1600 | <25 |
Serum PCR | N/A | negative | negative |
Test | Acute Infection | Persistent Infection | Notes |
---|---|---|---|
Immunofluorescence | Phase II IgG titre > 200 AND Phase II IgM titre > 50 OR Four-fold rise in phase II IgG (paired sera) | Phase I IgG titre > 800 OR Persistently elevated Phase I IgG/IgM | Gold standard |
PCR | Maybe positive early in the infective sequence (prior to antibody response) | Maybe performed on placental tissues/products, joint aspirate, sera | Does not differentiate acute vs. chronic |
Culture | Stains and immunofluorescence are not routinely performed | - | Highly infectious, requires PC3 facility |
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Marks, S.; Olenski, M. Q Fever in the First Trimester: A Case Report from Northern Rural New South Wales. Trop. Med. Infect. Dis. 2019, 4, 90. https://doi.org/10.3390/tropicalmed4020090
Marks S, Olenski M. Q Fever in the First Trimester: A Case Report from Northern Rural New South Wales. Tropical Medicine and Infectious Disease. 2019; 4(2):90. https://doi.org/10.3390/tropicalmed4020090
Chicago/Turabian StyleMarks, Sarah, and Maxwell Olenski. 2019. "Q Fever in the First Trimester: A Case Report from Northern Rural New South Wales" Tropical Medicine and Infectious Disease 4, no. 2: 90. https://doi.org/10.3390/tropicalmed4020090