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Open AccessCase Report

Acute Retroviral Syndrome Presenting with Hemolytic Anemia Induced by G6PD Deficiency

1
John H Stroger Jr Hospital of Cook County, Chicago, IL 60612, USA
2
Department of Medicine, Division of Infectious Diseases, University of Miami, Miller School of Medicine, Miami, Fl 33136, USA
*
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2019, 4(1), 6; https://doi.org/10.3390/tropicalmed4010006
Received: 9 December 2018 / Revised: 21 December 2018 / Accepted: 23 December 2018 / Published: 27 December 2018
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme defect described in humans. Hemolysis in affected patients is usually triggered by circumstances involving free radical damage. While acute HIV infection is known to be a state of overwhelming oxidative stress, virus-induced hemolytic events in G6PD-deficient patients has rarely been reported. Despite an estimated overall prevalence of 6.8%–13% of this disorder in the HIV population, clinically significant hemolysis has been largely attributed to the use of offending medications rather than HIV infection itself. Here, we present a patient whose first episode of G6PD deficiency-associated hemolysis occurred as the main presentation of acute HIV infection. View Full-Text
Keywords: acute HIV; acute retroviral syndrome; G6PD deficiency; hemolysis; hemolytic anemia acute HIV; acute retroviral syndrome; G6PD deficiency; hemolysis; hemolytic anemia
MDPI and ACS Style

Araujo, T.; Katiyar, V.; Gonzales Zamora, J.A. Acute Retroviral Syndrome Presenting with Hemolytic Anemia Induced by G6PD Deficiency. Trop. Med. Infect. Dis. 2019, 4, 6.

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