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Melioidosis in the Philippines
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Endemic Melioidosis in Southern China: Past and Present

State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Laboratory of Tropical Biomedicine and Biotechnology, School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou 571199, China
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2019, 4(1), 39;
Received: 16 November 2018 / Revised: 18 February 2019 / Accepted: 20 February 2019 / Published: 25 February 2019
(This article belongs to the Special Issue Global Burden and Challenges of Melioidosis)
Melioidosis is a severe tropical infectious disease caused by the soil-dwelling bacterium Burkholderia pseudomallei, predominantly endemic to Southeast Asia and northern Australia. Between the 1970s and the 1990s, the presence of B. pseudomallei causing melioidosis in humans and other animals was demonstrated in four coastal provinces in southern China: Hainan, Guangdong, Guangxi, and Fujian, although indigenous cases were rare and the disease failed to raise concern amongst local and national health authorities. In recent years, there has been a rise in the number of melioidosis cases witnessed in the region, particularly in Hainan. Meanwhile, although China has established and maintained an effective communicable disease surveillance system, it has not yet been utilized for melioidosis. Thus, the overall incidence, social burden and epidemiological features of the disease in China remain unclear. In this context, we present a comprehensive overview of both historical and current information on melioidosis in Southern China, highlighting the re-emergence of the disease in Hainan. Surveillance and management strategies for melioidosis should be promoted in mainland China, and more research should be conducted to provide further insights into the present situation. View Full-Text
Keywords: melioidosis; Burkholderia pseudomallei; epidemiology; China melioidosis; Burkholderia pseudomallei; epidemiology; China
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Zheng, X.; Xia, Q.; Xia, L.; Li, W. Endemic Melioidosis in Southern China: Past and Present. Trop. Med. Infect. Dis. 2019, 4, 39.

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