This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Open AccessReview
Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization
1
Laboratório de Medicina Veterinária Preventiva, Instituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil
2
Laboratório de Virologia Geral e Parasitologia, Centro de Ciências Biológicas e da Natureza, Universidade Federal do Acre, Rio Branco 69920-900, AC, Brazil
*
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2025, 10(7), 177; https://doi.org/10.3390/tropicalmed10070177 (registering DOI)
Submission received: 22 April 2025
/
Revised: 10 June 2025
/
Accepted: 19 June 2025
/
Published: 21 June 2025
Abstract
Lagochilascariasis is a neglected zoonotic helminthiasis, caused by Lagochilascaris minor, characterized by a complex and not well understood transmission cycle. This parasitic disease is endemic to Latin America, particularly Brazil, and is associated with rural and forested areas, where humans may serve as accidental hosts. The southeastern region of Pará state reports the highest number of cases, highlighting its epidemiological significance. Wildlife species, especially carnivores and rodents, play crucial roles as definitive and intermediate hosts, respectively. Although lagochilascariasis can lead to severe clinical manifestations, including chronic soft tissue infections and potential central nervous system involvement, it is likely underdiagnosed due to its similarity to fungal and bacterial diseases. The anthropization of the Amazon Biome, through deforestation and habitat fragmentation, coupled with increased human–wildlife interactions, may be influencing the epidemiology of this parasitosis. This review aims to summarize current knowledge of L. minor transmission routes, the role of wildlife in maintaining its cycle, and the impact of environmental changes on disease patterns. Such insights are vital for One Health strategies, which integrate human, animal, and environmental health approaches to mitigate the disease burden.
Share and Cite
MDPI and ACS Style
Salvarani, F.M.; da Cruz, K.P.P.; da Silva, F.R.C.; Daudt, C.
Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization. Trop. Med. Infect. Dis. 2025, 10, 177.
https://doi.org/10.3390/tropicalmed10070177
AMA Style
Salvarani FM, da Cruz KPP, da Silva FRC, Daudt C.
Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization. Tropical Medicine and Infectious Disease. 2025; 10(7):177.
https://doi.org/10.3390/tropicalmed10070177
Chicago/Turabian Style
Salvarani, Felipe Masiero, Karoline Petrini Pinheiro da Cruz, Flavio Roberto Chaves da Silva, and Cíntia Daudt.
2025. "Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization" Tropical Medicine and Infectious Disease 10, no. 7: 177.
https://doi.org/10.3390/tropicalmed10070177
APA Style
Salvarani, F. M., da Cruz, K. P. P., da Silva, F. R. C., & Daudt, C.
(2025). Lagochilascariasis: A Neglected Zoonosis in the Brazilian Amazon Biome and the Role of Wildlife in Its Epidemiological Chain Amidst Anthropization. Tropical Medicine and Infectious Disease, 10(7), 177.
https://doi.org/10.3390/tropicalmed10070177
Article Metrics
Article metric data becomes available approximately 24 hours after publication online.
, 
