This study investigates the sensitivity of the mechanistic-empirical flexible pavement design performance parameters such as cracking, rutting, and smoothness to mix factors for 11 categories of hot-mix asphalt (HMA) mixtures. For each category of HMA mixture, the variations in the pavement performances for different effective binder content (Vbe
), air void (Va
), voids-in-mineral aggregates (VMA), voids-filled-with asphalt (VFA), and asphalt content (AC) are examined by the AASHTOWare Pavement Mechanistic-Empirical Design, simply the AASHTOWare software analysis. Five types of distresses: international roughness index (IRI), total rutting, rutting in the HMA layer, bottom-up fatigue cracking, and top-down longitudinal fatigue cracking are considered in the analysis. Results show that the prediction of distresses values after 20-year of service life using the AASHTOWare software may differ by up to 170% for different specimens of a certain mix design. All distresses, except rutting, increase in Va
, VMA, and VFA. Rutting in HMA increases with an increase in VMA and VFA, and is insensitive to Vbe
, and AC in the study range of these parameters.
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