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Open AccessArticle

Changes in Fixation Stability with Time during Binocular and Monocular Viewing in Maculopathy

1
Krembil Research Institute, Toronto Western Hospital, Toronto, ON M5T 2S8, Canada
2
Faculty of Medicine, University of Toronto, ON M5S 1A8, Canada
3
Department of Ophthalmology and Vision Sciences, University of Toronto, ON M5T 2S8, Canada
*
Author to whom correspondence should be addressed.
Vision 2018, 2(4), 40; https://doi.org/10.3390/vision2040040
Received: 8 September 2018 / Revised: 13 October 2018 / Accepted: 21 October 2018 / Published: 23 October 2018
The purpose of this study was to examine changes in fixation stability over time during binocular and monocular viewing in patients with age-related macular degeneration (AMD). Seventeen patients with AMD and 17 controls were enrolled. Using an EyeLink eyetracker (SR Research Ltd., Mississauga, Ontario, Canada), fixation stability was recorded binocularly and monocularly with each eye for a duration of 15 s while the fellow eye was covered. Fixation stability was analyzed over 3 s intervals for each condition using a 68% bivariate contour ellipse area. Fixation stability did not change with time during binocular viewing for both groups, both monocular conditions for the control group, and monocular viewing with the better eye for the AMD group. However, during monocular viewing with the worse eye, the test of within-subject contrasts showed linear improvement in fixation stability with time (p = 0.016). In conclusion, in patients with AMD, monocular fixational control with the worse eye is poor, but improves with time. View Full-Text
Keywords: central vision loss; age-related macular degeneration; fixation stability; worse eye; preferred retinal locus; fixation duration central vision loss; age-related macular degeneration; fixation stability; worse eye; preferred retinal locus; fixation duration
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Samet, S.; González, E.G.; Mandelcorn, M.S.; Brent, M.H.; Tarita-Nistor, L. Changes in Fixation Stability with Time during Binocular and Monocular Viewing in Maculopathy. Vision 2018, 2, 40.

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