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Review

Intra-Articular Injections in Knee Osteoarthritis: A Review of Literature

Department of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Traumatology, P.O. “Policlinico Gaspare Rodolico”, University of Catania, 95123 Catania, Italy
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Academic Editor: Deodato Assanelli
J. Funct. Morphol. Kinesiol. 2021, 6(1), 15; https://doi.org/10.3390/jfmk6010015
Received: 28 December 2020 / Revised: 30 January 2021 / Accepted: 1 February 2021 / Published: 3 February 2021
(This article belongs to the Special Issue Role of Exercises in Musculoskeletal Disorders—3th Edition)
Knee osteoarthritis (OA) is a chronic, degenerative, and progressive disease of articular cartilage, producing discomfort and physical disability in older adults. Thirteen percent of elderly people complain of knee OA. Management options for knee OA could be divided into the following categories: conservative, pharmacological, procedural, and surgical. Joint replacement is the gold standard, reserved for severe grades of knee OA, due to its complications rate and increased risk of joint revision. A nonsurgical approach is the first choice in the adult population with cartilage damage and knee OA. Yearly, more than 10% of knee OA-affected patients undergo intra-articular injections of different drugs, especially within three months after OA diagnosis. Several molecules, such as corticosteroids injection, hyaluronic acid (HA), and platelet-rich plasma (PRP), are managed to reduce the symptoms of patients with knee OA. The aim of this review was to offer an overview of intra-articular injections used for the treatment of OA and report the conventional pharmacological products used. View Full-Text
Keywords: knee osteoarthritis; injection therapy; intra-articular injections; corticosteroids; hyaluronic acid; platelet-rich plasma knee osteoarthritis; injection therapy; intra-articular injections; corticosteroids; hyaluronic acid; platelet-rich plasma
MDPI and ACS Style

Testa, G.; Giardina, S.M.C.; Culmone, A.; Vescio, A.; Turchetta, M.; Cannavò, S.; Pavone, V. Intra-Articular Injections in Knee Osteoarthritis: A Review of Literature. J. Funct. Morphol. Kinesiol. 2021, 6, 15. https://doi.org/10.3390/jfmk6010015

AMA Style

Testa G, Giardina SMC, Culmone A, Vescio A, Turchetta M, Cannavò S, Pavone V. Intra-Articular Injections in Knee Osteoarthritis: A Review of Literature. Journal of Functional Morphology and Kinesiology. 2021; 6(1):15. https://doi.org/10.3390/jfmk6010015

Chicago/Turabian Style

Testa, Gianluca, Serena M.C. Giardina, Annalisa Culmone, Andrea Vescio, Matteo Turchetta, Salvatore Cannavò, and Vito Pavone. 2021. "Intra-Articular Injections in Knee Osteoarthritis: A Review of Literature" Journal of Functional Morphology and Kinesiology 6, no. 1: 15. https://doi.org/10.3390/jfmk6010015

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