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Open AccessConcept Paper

Clinical Application of 2D Speckle Tracking Strain for Assessing Cardio-Toxicity in Oncology

Clinical and Experimental Department, Sports Medicine and Exercise Center, School of Sports Medicine, 50100 Florence, Italy
Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy
Author to whom correspondence should be addressed.
Academic Editor: Giuseppe Musumeci
J. Funct. Morphol. Kinesiol. 2016, 1(4), 343-354;
Received: 13 August 2016 / Revised: 13 September 2016 / Accepted: 20 September 2016 / Published: 11 October 2016
(This article belongs to the Special Issue Tailored Exercise in Patients with Chronic Diseases)
Echocardiography has recently undergone innovations due to the availability of deformation parameters as strain, strain rate, torsion and rotation that allow an accurate assessment of myocardial function. Because of this general progress, the importance of myocardial deformation parameters has been highlighted, and some aspects of their clinical and research applications have recently been considered for the daily management of many acute and chronic metabolic diseases. The deformation parameters are largely proposed for the early detection of myocardial dysfunction, especially in the case of patients being completely asymptomatic. Strain analysis is extensively applied to cardiomyopathies, to coronary artery disease, or to the evaluation of the “forgotten chambers”, such as the right ventricles and atria. More recently, several other clinical contexts, like non-communicable chronic diseases (NCCD), have actually been benefitting from specific evaluation by strain analysis. Lately, some specific aspects of strain evaluation, particularly Global Longitudinal Strain (GLS) have been shown to provide useful information of clinical relevance in the case of cancer patients. This paper presents an initial review of the recent applications of strain analysis in cardio-oncology, in order to share the recent experience in this field and to support the role of these parameters in cardio-oncology. View Full-Text
Keywords: speckle tracking; myocardial function; cardio-oncology speckle tracking; myocardial function; cardio-oncology
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Stefani, L.; Pedrizzetti, G.; Galanti, G. Clinical Application of 2D Speckle Tracking Strain for Assessing Cardio-Toxicity in Oncology. J. Funct. Morphol. Kinesiol. 2016, 1, 343-354.

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