The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights on Recent Papers in Articular Cartilage Tissue Engineering and Mechanical Stimulation
Abstract
:1. Introduction
2. Papers Published in 2015 and 2016 Regarding the Mechanical Stimulation and Its Influence on Chondrogenesis
2.1. Effects of Intermittent Hydrostatic Pressure on Chondrogenic Differentiation
2.2. Cell Surface Primary Cilia Influence on Mechanical Sensitivity of Chondroprogenitors and Hypertrophic Chondrocytes
2.3. Impact of Electromagnetic Field Frequencies on Cartilage Regeneration
2.4. Effect of Dynamic Culture and Periodic Compression on Human Mesenchymal Stem Cell Chondrogenesis
2.5. The Effect of Mechanical Stimulation and Adenoviral-Mediated Over-Expression of BMP-2 on the Chondrogenesis of Human Articular Cartilage Progenitor Cells
2.6. Ageing and Reduction of Mechanically-Induced Smad2/3P Signaling Activation in Articular Cartilage
Acknowledgments
Author Contributions
Conflicts of Interest
Abbreviations
AC | Articular Cartilage |
ACPCs | Articular Cartilage Progenitor Cells |
BMP | Bone Morphogenic Protein |
FPSCs | Fat Pad-Derived Stem Cells |
Hmsc | Human mesenchymal stem cell |
IFT88 | Intraflagellar Transport Protein 88 |
IHP | Intermittent Hydrostatic Pressure |
OA | Osteoarthritis |
TPS | Tubular Perfusion System |
References
- Vos, T.; Flaxman, A.D.; Naghavi, M.; Lozano, R.; Michaud, C.; Ezzati, M.; Shibuya, K.; Salomon, J.A.; Abdalla, S.; Aboyans, V.; et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012, 380, 2163–2196. [Google Scholar] [CrossRef]
- Grad, S.; Eglin, D.; Alini, M.; Stoddart, M.J. Physical stimulation of chondrogenic cells in vitro: A review. Clin. Orthop. Relat. Res. 2011, 469, 2764–2772. [Google Scholar] [CrossRef] [PubMed]
- Schätti, O.; Grad, S.; Goldhahn, J.; Salzmann, G.; Li, Z.; Alini, M.; Stoddart, M.J. A combination of shear and dynamic compression leads to mechanically induced chondrogenesis of human mesenchymal stem cells. Eur. Cell. Mater. 2011, 22, 214–225. [Google Scholar] [PubMed]
- Guo, T.; Yu, L.; Lim, C.G.; Goodley, A.S.; Xiao, X.; Placone, J.K.; Ferlin, K.M.; Nguyen, B.B.; Hsieh, A.H.; Fisher, J.P. Effect of dynamic culture and periodic compression on human mesenchymal stem cell proliferation and chondrogenesis. Ann. Biomed. Eng. 2015. [Google Scholar] [CrossRef] [PubMed]
- Deren, M.E.; Yang, X.; Guan, Y.; Chen, Q. Biological and chemical removal of primary cilia affects mechanical activation of chondrogenesis markers in chondroprogenitors and hypertrophic chondrocytes. Int. J. Mol. Sci. 2016, 17. [Google Scholar] [CrossRef] [PubMed]
- Yi, H.G.; Kang, K.S.; Hong, J.M.; Jang, J.; Park, M.N.; Jeong, Y.H.; Cho, D.W. Effects of electromagnetic field frequencies on chondrocytes in 3D cell-printed composite constructs. J. Biomed. Mater. Res. 2016. [Google Scholar] [CrossRef] [PubMed]
- Li, Y.; Zhou, J.; Yang, X.; Jiang, Y.; Gui, J. Intermittent hydrostatic pressure maintains and enhances the chondrogenic differentiation of cartilage progenitor cells cultivated in alginate beads. Dev. Growth. Differ. 2016, 58, 180–193. [Google Scholar] [CrossRef] [PubMed]
- Lee, C.H.; Cook, J.L.; Mendelson, A.; Moioli, E.K.; Yao, H.; Mao, J.J. Regeneration of the articular surface of the rabbit synovial joint by cell homing: A proof of concept study. Lancet 2010, 376, 440–448. [Google Scholar] [CrossRef]
- Ripamonti, U.; Duarte, R.; Ferretti, C. Re-evaluating the induction of bone formation in primates. Biomaterials 2014, 35, 9407–9422. [Google Scholar] [CrossRef] [PubMed]
- Ripamonti, U.; Dix-Peek, T.; Parak, R.; Milner, B.; Duarte, R. Profiling bone morphogenetic proteins and transforming growth factor-βs by hTGF-β3 pre-treated coral-derived macroporous constructs: The power of one. Biomaterials 2015, 49, 90–102. [Google Scholar] [CrossRef] [PubMed]
- Neumann, A.J.; Gardner, O.F.; Williams, R.; Alini, M.; Archer, C.W.; Stoddart, M.J. Human articular cartilage progenitor cells are responsive to mechanical stimulation and adenoviral-mediated overexpression of bone-morphogenetic protein 2. PLoS ONE 2015, 10, e0136229. [Google Scholar]
- Madej, W.; van Caam, A.; Blaney Davidson, E.N.; Hannink, G.; Buma, P.; van der Kraan, P.M. Ageing is associated with reduction of mechanically-induced activation of Smad2/3P signaling in articular cartilage. Osteoarthr. Cartil. 2016, 24, 146–157. [Google Scholar] [CrossRef] [PubMed]
© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
Share and Cite
Szychlinska, M.A.; Vadalà, G.; Workman, V.; Ripamonti, U.; Mendes, A.F.; Stoddart, M.J.; Alini, M. The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights on Recent Papers in Articular Cartilage Tissue Engineering and Mechanical Stimulation. J. Funct. Morphol. Kinesiol. 2016, 1, 162-166. https://doi.org/10.3390/jfmk1020162
Szychlinska MA, Vadalà G, Workman V, Ripamonti U, Mendes AF, Stoddart MJ, Alini M. The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights on Recent Papers in Articular Cartilage Tissue Engineering and Mechanical Stimulation. Journal of Functional Morphology and Kinesiology. 2016; 1(2):162-166. https://doi.org/10.3390/jfmk1020162
Chicago/Turabian StyleSzychlinska, Marta Anna, Gianluca Vadalà, Victoria Workman, Ugo Ripamonti, Alexandrina Ferreira Mendes, Martin J. Stoddart, and Mauro Alini. 2016. "The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights on Recent Papers in Articular Cartilage Tissue Engineering and Mechanical Stimulation" Journal of Functional Morphology and Kinesiology 1, no. 2: 162-166. https://doi.org/10.3390/jfmk1020162
APA StyleSzychlinska, M. A., Vadalà, G., Workman, V., Ripamonti, U., Mendes, A. F., Stoddart, M. J., & Alini, M. (2016). The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights on Recent Papers in Articular Cartilage Tissue Engineering and Mechanical Stimulation. Journal of Functional Morphology and Kinesiology, 1(2), 162-166. https://doi.org/10.3390/jfmk1020162