Next Article in Journal / Special Issue
Ground-Coupled Natural Circulating Devices (Thermosiphons): A Review of Modeling, Experimental and Development Studies
Previous Article in Journal
Microfluidics and Nanofluidics
Previous Article in Special Issue
Temperature Distribution through a Nanofilm by Means of a Ballistic-Diffusive Approach
Open AccessReview

Molecular Thermodynamics Using Nuclear Magnetic Resonance (NMR) Spectroscopy

Department of Chemistry, California State University, Fresno, CA 93740, USA
Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, CA 95616, USA
Inventions 2019, 4(1), 13;
Received: 18 December 2018 / Revised: 11 February 2019 / Accepted: 14 February 2019 / Published: 21 February 2019
(This article belongs to the Special Issue Thermodynamics in the 21st Century)
Nuclear magnetic resonance (NMR) spectroscopy is perhaps the most widely used technology from the undergraduate teaching labs in organic chemistry to advanced research for the determination of three-dimensional structure as well as dynamics of biomolecular systems... The NMR spectrum of a molecule under a given experimental condition is unique, providing both quantitative and structural information. In particular, the quantitative nature of NMR spectroscopy offers the ability to follow a reaction pathway of the given molecule in a dynamic process under well-defined experimental conditions. To highlight the use of NMR when determining the molecular thermodynamic parameters, a review of three distinct applications developed from our laboratory is presented. These applications include the thermodynamic parameters of (a) molecular oxidation from time-dependent kinetics, (b) intramolecular rotation, and (c) intermolecular exchange. An experimental overview and the method of data analysis are provided so that these applications can be adopted in a range of molecular systems. View Full-Text
Keywords: NMR; thermodynamics; chemical exchange; Eyring equation NMR; thermodynamics; chemical exchange; Eyring equation
Show Figures

Graphical abstract

MDPI and ACS Style

Krishnan, V.V. Molecular Thermodynamics Using Nuclear Magnetic Resonance (NMR) Spectroscopy. Inventions 2019, 4, 13.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop