An Anthropomorphic Digital Reference Object (DRO) for Simulation and Analysis of Breast DCE MRI Techniques
Abstract
:1. Introduction
2. Materials and Methods
2.1. Breast MRI DRO Overview
- Different MRI input images including anatomy and chemical species content
- Different coil sensitivity profiles
- Contrast enhancement based on user desired kinetic models
- Simulation of MRI physics
- Simulation of k-space sampling in both time and space.
2.2. Anatomy Module
2.3. Physiology Module
2.4. MRI System Module
2.5. Simulator Module
2.6. Example Simulations Using the Breast DRO
2.6.1. Simulation 1
2.6.2. Simulation 2
2.6.3. Simulation 3
2.6.4. Simulation 4
2.6.5. Simulation 5
3. Results
3.1. Simulation 1
3.2. Simulation 2
3.3. Simulation 3
3.4. Simulation 4
3.5. Simulation 5
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Henze Bancroft, L.; Holmes, J.; Bosca-Harasim, R.; Johnson, J.; Wang, P.; Korosec, F.; Block, W.; Strigel, R. An Anthropomorphic Digital Reference Object (DRO) for Simulation and Analysis of Breast DCE MRI Techniques. Tomography 2022, 8, 1005-1023. https://doi.org/10.3390/tomography8020081
Henze Bancroft L, Holmes J, Bosca-Harasim R, Johnson J, Wang P, Korosec F, Block W, Strigel R. An Anthropomorphic Digital Reference Object (DRO) for Simulation and Analysis of Breast DCE MRI Techniques. Tomography. 2022; 8(2):1005-1023. https://doi.org/10.3390/tomography8020081
Chicago/Turabian StyleHenze Bancroft, Leah, James Holmes, Ryan Bosca-Harasim, Jacob Johnson, Pingni Wang, Frank Korosec, Walter Block, and Roberta Strigel. 2022. "An Anthropomorphic Digital Reference Object (DRO) for Simulation and Analysis of Breast DCE MRI Techniques" Tomography 8, no. 2: 1005-1023. https://doi.org/10.3390/tomography8020081