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Feasibility of Ultra-High Resolution Supra-Aortic CT Angiography: An Assessment of Diagnostic Image Quality and Radiation Dose

Department of Neuroradiology, University Medical Center Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
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Author to whom correspondence should be addressed.
Academic Editor: Emilio Quaia
Tomography 2021, 7(4), 711-720; https://doi.org/10.3390/tomography7040059
Received: 6 October 2021 / Revised: 27 October 2021 / Accepted: 27 October 2021 / Published: 1 November 2021
(This article belongs to the Section Brain Imaging)
(1) Background: To evaluate diagnostic image quality and radiation exposure of ultra-high resolution cerebral Computed-Tomography (CT) angiography (CTA) obtained on an ultra-high resolution computed tomography scanner (UHR-CT). (2) Methods: Fifty consecutive patients with UHR-CTA were enrolled. Image reconstruction was processed with a 1024 × 1024 matrix and a slice thickness of 0.25 mm. Quantitative analyses comprising CT values, contrast–noise ratio (CNR) and signal-to-noise ratio (SNR) were performed. Subjective assessment of image quality, vessel contrast, noise, artefacts and delineation of different sized vessels were assessed by two readers on a 4-point scale. Radiation exposure was determined. (3) Results: Hounsfield values (ACI: 461.8 ± 16.8 HU; MCA: 406.1 ± 24.2 HU; BA: 412.2 ± 22.3 HU), SNR (ACI: 35.4 ± 13.1; MCA: 20.8 ± 12.4; BA: 23.7 ± 12.9) and CNR (ACI: 48.7 ± 21; MCA: 63.9 ± 26.9; BA: 48.1 ± 21.4) were remarkably high in all segments. Subjective analysis by two raters (fair agreement, k = 0.26) indicated excellent image qualities (image quality = 4; contrast = 4; noise = 3; artefacts = 4).Our analysis revealed a notably high traceability of the cerebral perforators (3 Points). Radiation exposure was at moderate dose levels (effective dose = 2.5 ± 0.6mSv). (4) Conclusions: UHR-CTA generates highly valuable image qualities that allow the depiction of vessels including cerebral perforators at acceptable dose levels. The UHR-CTA may therefore enhance the detection of small cerebral pathologies and may improve interpretability, especially in settings where high image qualities are crucial for the diagnostic accuracy. View Full-Text
Keywords: computed tomography; computed tomography angiography; cerebral arteries; stroke; contrast media; image enhancement; radiation dosage computed tomography; computed tomography angiography; cerebral arteries; stroke; contrast media; image enhancement; radiation dosage
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MDPI and ACS Style

Ucar, F.A.; Frenzel, M.; Abello Mercado, M.A.; Altmann, S.; Reder, S.; Brockmann, C.; Brockmann, M.A.; Othman, A.E. Feasibility of Ultra-High Resolution Supra-Aortic CT Angiography: An Assessment of Diagnostic Image Quality and Radiation Dose. Tomography 2021, 7, 711-720. https://doi.org/10.3390/tomography7040059

AMA Style

Ucar FA, Frenzel M, Abello Mercado MA, Altmann S, Reder S, Brockmann C, Brockmann MA, Othman AE. Feasibility of Ultra-High Resolution Supra-Aortic CT Angiography: An Assessment of Diagnostic Image Quality and Radiation Dose. Tomography. 2021; 7(4):711-720. https://doi.org/10.3390/tomography7040059

Chicago/Turabian Style

Ucar, Felix A., Marius Frenzel, Mario A. Abello Mercado, Sebastian Altmann, Sebastian Reder, Carolin Brockmann, Marc A. Brockmann, and Ahmed E. Othman 2021. "Feasibility of Ultra-High Resolution Supra-Aortic CT Angiography: An Assessment of Diagnostic Image Quality and Radiation Dose" Tomography 7, no. 4: 711-720. https://doi.org/10.3390/tomography7040059

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