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Open AccessFeature PaperReview

Image-Guided Cancer Nanomedicine

by Dong-Hyun Kim 1,2
1
Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
2
Robert H. Lurie Comprehensive Cancer Center, Chicago, IL 60611, USA
J. Imaging 2018, 4(1), 18; https://doi.org/10.3390/jimaging4010018
Received: 6 November 2017 / Revised: 3 January 2018 / Accepted: 9 January 2018 / Published: 11 January 2018
(This article belongs to the Special Issue Nanoparticles and Medical Imaging for Image Guided Medicine)
Multifunctional nanoparticles with superior imaging properties and therapeutic effects have been extensively developed for the nanomedicine. However, tumor-intrinsic barriers and tumor heterogeneity have resulted in low in vivo therapeutic efficacy. The poor in vivo targeting efficiency in passive and active targeting of nano-therapeutics along with the toxicity of nanoparticles has been a major problem in nanomedicine. Recently, image-guided nanomedicine, which can deliver nanoparticles locally using non-invasive imaging and interventional oncology techniques, has been paid attention as a new opportunity of nanomedicine. This short review will discuss the existing challenges in nanomedicine and describe the prospects for future image-guided nanomedicine. View Full-Text
Keywords: nanomedicine; image; image-guided nanomedicine; nanoparticles; cancer nanomedicine; image; image-guided nanomedicine; nanoparticles; cancer
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Kim, D.-H. Image-Guided Cancer Nanomedicine. J. Imaging 2018, 4, 18.

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