Comparative Fungicidal Activities of N-Chlorotaurine and Conventional Antiseptics against Candida spp. Isolated from Vulvovaginal Candidiasis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Test Microorganisms
2.2. Test Products
2.3. Antiseptic Activity Assay
2.4. Validation Procedures
2.5. Statistics
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Number of Strains | Number of Fluconazole Resistant Strains | Number of Susceptible Dose-Dependent | |
---|---|---|---|
C. albicans | 29 | - | 1 (3.44%) |
C. glabrata | 8 | 2 (25%) | 2 (25%) |
C. krusei | 1 | - | 1 (100%) |
C. tropicalis | 2 | - | - |
C. famata | 1 | - | - |
C. kefyr | 2 | - | - |
C. lusitaniae | 1 | - | - |
Total | 44 | 2 (4.54%) | 4 (9.09%) |
Antiseptic | C. albicans (n = 29) | C. non-albicans (n = 15) |
---|---|---|
CHX 1.6% | 0.1914 ± 0.0014 | 0.1961 ± 0.0012 |
OCT 0.08% | 0.1890 ± 0.0017 | 0.1884 ± 0.0017 |
PVP-I 8% | 0.1243 ± 0.0015 | 0.1593 ± 0.0018 |
NCT 0.1% | 0.0287 ± 0.0001 | 0.0086 ± 0.0001 |
Boric acid 8% | 0.0132 ± 0.0002 | 0.0066 ± 0.0001 |
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Hacioglu, M.; Oyardi, O.; Yilmaz, F.N.; Nagl, M. Comparative Fungicidal Activities of N-Chlorotaurine and Conventional Antiseptics against Candida spp. Isolated from Vulvovaginal Candidiasis. J. Fungi 2022, 8, 682. https://doi.org/10.3390/jof8070682
Hacioglu M, Oyardi O, Yilmaz FN, Nagl M. Comparative Fungicidal Activities of N-Chlorotaurine and Conventional Antiseptics against Candida spp. Isolated from Vulvovaginal Candidiasis. Journal of Fungi. 2022; 8(7):682. https://doi.org/10.3390/jof8070682
Chicago/Turabian StyleHacioglu, Mayram, Ozlem Oyardi, Fatima Nur Yilmaz, and Markus Nagl. 2022. "Comparative Fungicidal Activities of N-Chlorotaurine and Conventional Antiseptics against Candida spp. Isolated from Vulvovaginal Candidiasis" Journal of Fungi 8, no. 7: 682. https://doi.org/10.3390/jof8070682