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J. Fungi 2018, 4(2), 55;

Sporotrichin Skin Test for the Diagnosis of Sporotrichosis

Dermatology Service & Mycology Department, Hospital General de México, “Dr. Eduardo Liceaga”, Balmis 148, Colonia Doctores, Ciudad de México 06726, Mexico
Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico
Medicine School, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru
Internal Medicine Department, Hospital General de Zona 29, Instituto Mexicano del Seguro Social, Ciudad de México 07950, Mexico
Current address: Fondo Nacional de Desarrollo Científico y Tecnológico y de Innovación Tecnológica (FONDECYT), CONCYTEC, Lima 51, Peru.
Authors to whom correspondence should be addressed.
Received: 1 April 2018 / Revised: 3 May 2018 / Accepted: 5 May 2018 / Published: 9 May 2018
(This article belongs to the Special Issue Sporothrix and Sporotrichosis)
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Sporotrichosis is the most common implantation mycosis caused by several species of the Sporothrix schenckii complex. The gold standard for diagnosis is concerned with the isolation of the fungus; although, fresh examinations, staining, and biopsies are also helpful for this purpose. The sporotrichin is an antigenic complex comprised of a peptide-rhamnomannan, which is relevant with respect to pathogenic fungi; it is primarily used for serological and skin testing. We present a study regarding the use of sporotrichin as a diagnostic aid for cutaneous sporotrichosis. Furthermore, 138 cases with suspicion of sporotrichosis were included, 55 of which were proven through cultures. Moreover, out of these 55 cases, 52 (94.5%) tested positive for sporotrichin, while the negative cases corresponded to the disseminated cutaneous forms. We observed a sensitivity of 94.5% and a specificity of 95.2%. We consider that the use of sporotrichin as a skin test helps us as an auxiliary diagnosis before a positive sample culture. View Full-Text
Keywords: sporotrichosis; sporotrichin; skin test; Sporothrix schenckii sporotrichosis; sporotrichin; skin test; Sporothrix schenckii

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Bonifaz, A.; Toriello, C.; Araiza, J.; Ramírez-Soto, M.C.; Tirado-Sánchez, A. Sporotrichin Skin Test for the Diagnosis of Sporotrichosis. J. Fungi 2018, 4, 55.

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