Next Article in Journal
The Fungus among Us: Cryptococcus neoformans and Cryptococcus gattii Ecological Modeling for Colombia
Next Article in Special Issue
Role of New Antifungal Agents in the Treatment of Invasive Fungal Infections in Transplant Recipients: Isavuconazole and New Posaconazole Formulations
Previous Article in Journal
Candida glabrata, Friend and Foe
Previous Article in Special Issue
Diagnostic Modalities for Invasive Mould Infections among Hematopoietic Stem Cell Transplant and Solid Organ Recipients: Performance Characteristics and Practical Roles in the Clinic
Open AccessReview

Pneumocystis Pneumonia in Solid-Organ Transplant Recipients

by Xavier Iriart 1,2,3,4,*, Marine Le Bouar 1,2,3,4, Nassim Kamar 2,4,5,† and Antoine Berry 1,2,3,4,*,†
1
Department of Parasitology-Mycology, Centre Hospitalier Universitaire de Toulouse, Hôpital Purpan, Institut Fédératif de biologie (IFB), 330 avenue de Grande Bretagne, TSA 40031, Toulouse 31059, France
2
INSERM U1043, Toulouse F-31300, France
3
CNRS UMR5282, Toulouse F-31300, France
4
Université de Toulouse, UPS, Centre de Physiopathiologie de Toulouse Purpan (CPTP), Toulouse F-31300, France
5
Department of Nephrology and Organ Transplantation, CHU Rangueil, TSA 50032, Toulouse 31059, France
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Shmuel Shoham
J. Fungi 2015, 1(3), 293-331; https://doi.org/10.3390/jof1030293
Received: 17 June 2015 / Revised: 1 September 2015 / Accepted: 2 September 2015 / Published: 28 September 2015
(This article belongs to the Special Issue Fungal Infections in Transplant Recipients)
Pneumocystis pneumonia (PCP) is well known and described in AIDS patients. Due to the increasing use of cytotoxic and immunosuppressive therapies, the incidence of this infection has dramatically increased in the last years in patients with other predisposing immunodeficiencies and remains an important cause of morbidity and mortality in solid-organ transplant (SOT) recipients. PCP in HIV-negative patients, such as SOT patients, harbors some specificity compared to AIDS patients, which could change the medical management of these patients. This article summarizes the current knowledge on the epidemiology, risk factors, clinical manifestations, diagnoses, prevention, and treatment of Pneumocystis pneumonia in solid-organ transplant recipients, with a particular focus on the changes caused by the use of post-transplantation prophylaxis. View Full-Text
Keywords: Pneumocystis jirovecii; Pneumocystis pneumonia; transplantation; solid-organ transplant recipients Pneumocystis jirovecii; Pneumocystis pneumonia; transplantation; solid-organ transplant recipients
Show Figures

Figure 1

MDPI and ACS Style

Iriart, X.; Bouar, M.L.; Kamar, N.; Berry, A. Pneumocystis Pneumonia in Solid-Organ Transplant Recipients. J. Fungi 2015, 1, 293-331.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop