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Open AccessArticle
Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases
by
Axel Rentzsch
Axel Rentzsch 1,*
,
Sophie Schubert
Sophie Schubert 2,
Jochen Pfeifer
Jochen Pfeifer 1
,
Migdat Mustafi
Migdat Mustafi 3 and
Hashim Abdul-Khaliq
Hashim Abdul-Khaliq 1
1
Clinic for Pediatric Cardiology, Saarland University Hospital, 66421 Homburg, Germany
2
Department of Pediatrics, Clinic Donaustadt, 1220 Vienna, Austria
3
Department of Thoracic and Cardiovascular Surgery, Saarland University Hospital, 66421 Homburg, Germany
*
Author to whom correspondence should be addressed.
J. Cardiovasc. Dev. Dis. 2026, 13(9), 473; https://doi.org/10.3390/jcdd13090473 (registering DOI)
Submission received: 15 August 2026
/
Revised: 12 September 2026
/
Accepted: 17 September 2026
/
Published: 20 September 2026
Abstract
Background: For infants who underwent surgical coarctation repair and required balloon angioplasty for recoarctation within the first year of life, data are limited—especially regarding safety, mid-term efficacy, and reintervention risk factors. Methods: This retrospective study included the data of 33 infants who underwent surgical correction of CoA within their first three months of life and whose first cardiac catheterization for recoarctation—defined by a systolic echocardiographic gradient of ≥20 mmHg—was performed within the first year of life. Results: The median age at repair was 21 days, and that at angioplasty was 77 days. The peak systolic gradient decreased from 40.0 to 21.0 mmHg (p < 0.001), and the mean gradient decreased from 13.9 to 6.7 mmHg (p = 0.02). The aortic stenotic diameter increased from 3.2 to 4.1 mm (p < 0.001), and the z score increased from −4.2 to −2.7 (p < 0.001). Right arm systolic blood pressure dropped from 111.8 to 88.2 mmHg (p < 0.001); 7% of cases remained hypertensive. Complications occurred in 12% of patients, and reintervention was needed in 39.4%. Association with other congenital heart disease increased reintervention risk (OR 4.51). Follow-up gradients were as follows: 27.4 ± 10.2 mmHg (1 year), 24.6 ± 8.3 mmHg (2 years), 32.8 ± 18.8 mmHg (5 years), and 35.4 ± 23.2 mmHg (7 years). Conclusions: Early balloon angioplasty for postoperative recoarctation is safe, effective, and repeatable, with a high procedural success rate and sustained hemodynamic improvements. Reinterventions were more common in patients with additional CHD, though outcomes remained favorable.
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MDPI and ACS Style
Rentzsch, A.; Schubert, S.; Pfeifer, J.; Mustafi, M.; Abdul-Khaliq, H.
Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases. J. Cardiovasc. Dev. Dis. 2026, 13, 473.
https://doi.org/10.3390/jcdd13090473
AMA Style
Rentzsch A, Schubert S, Pfeifer J, Mustafi M, Abdul-Khaliq H.
Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases. Journal of Cardiovascular Development and Disease. 2026; 13(9):473.
https://doi.org/10.3390/jcdd13090473
Chicago/Turabian Style
Rentzsch, Axel, Sophie Schubert, Jochen Pfeifer, Migdat Mustafi, and Hashim Abdul-Khaliq.
2026. "Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases" Journal of Cardiovascular Development and Disease 13, no. 9: 473.
https://doi.org/10.3390/jcdd13090473
APA Style
Rentzsch, A., Schubert, S., Pfeifer, J., Mustafi, M., & Abdul-Khaliq, H.
(2026). Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases. Journal of Cardiovascular Development and Disease, 13(9), 473.
https://doi.org/10.3390/jcdd13090473
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