Autologous Bone Marrow Mononuclear Cells (BMMCs) for the Treatment of Uncomplicated Grade 2 Ununited Anconeal Process (UAP) in Six Dogs: Preliminary Results
Abstract
:1. Introduction
2. Materials and Methods
2.1. Inclusion Criteria
2.2. Clinical Examination
2.3. X-ray and CT Evaluation
2.4. Bone Marrow Harvesting
2.5. Bone Marrow Processing and BMMC Isolation
2.6. BMMC Injection
2.7. Post-Surgical Regimen
2.8. Complications
3. Results
3.1. X-ray Results
3.2. CT Results
3.3. Bone Marrow Results
3.4. Follow-Up
3.5. Microradiographic Assessment
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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X-ray | Surgery | |
---|---|---|
Grade 1 (1°) | Opaque fissure | Completely attached anconeal process |
Grades 2 and 3 (2–3°) | Transparent fissure | Low mobility anconeal process |
Grades 4 and 5 (4–5°) | Incongruous anconeal process with dislocation and bone reabsorption | Detached anconeal process |
Variable | Mean | St Dev | Median | Interquantile Range |
---|---|---|---|---|
Age (months) | 7.7 | 0.8 | 7.5 | 2.0 |
Bone marrow volume (ml) | 34.33 | 5.96 | 35.00 | 16.00 |
No. BMMCs | 2.57 × 107 | 1.30 × 107 | 2.30 × 107 | 3.70 × 107 |
UFC/ml | 528.5 | 224.3 | 495 | 500 |
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Crovace, A.M.; Lacitignola, L.; Di Comite, M.; Esposito, C.; Guarracino, A.; Francioso, E.; Staffieri, F.; Crovace, A. Autologous Bone Marrow Mononuclear Cells (BMMCs) for the Treatment of Uncomplicated Grade 2 Ununited Anconeal Process (UAP) in Six Dogs: Preliminary Results. Vet. Sci. 2021, 8, 214. https://doi.org/10.3390/vetsci8100214
Crovace AM, Lacitignola L, Di Comite M, Esposito C, Guarracino A, Francioso E, Staffieri F, Crovace A. Autologous Bone Marrow Mononuclear Cells (BMMCs) for the Treatment of Uncomplicated Grade 2 Ununited Anconeal Process (UAP) in Six Dogs: Preliminary Results. Veterinary Sciences. 2021; 8(10):214. https://doi.org/10.3390/vetsci8100214
Chicago/Turabian StyleCrovace, Alberto Maria, Luca Lacitignola, Mariasevera Di Comite, Cosimo Esposito, Alessandro Guarracino, Edda Francioso, Francesco Staffieri, and Antonio Crovace. 2021. "Autologous Bone Marrow Mononuclear Cells (BMMCs) for the Treatment of Uncomplicated Grade 2 Ununited Anconeal Process (UAP) in Six Dogs: Preliminary Results" Veterinary Sciences 8, no. 10: 214. https://doi.org/10.3390/vetsci8100214