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Open AccessArticle

Bio-Inspired Multi-Functional Drug Transport Design Concept and Simulations

1
College of Engineering, University of Georgia, Athens, GA 30602, USA
2
Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA
3
Previously at Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA
*
Author to whom correspondence should be addressed.
This paper is an extended version of our paper published in ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, Washington, DC, USA, 11–13 September 2013.
Academic Editor: Hu Yang
Bioengineering 2017, 4(2), 37; https://doi.org/10.3390/bioengineering4020037
Received: 17 February 2017 / Revised: 18 April 2017 / Accepted: 20 April 2017 / Published: 25 April 2017
(This article belongs to the Special Issue Advanced Drug Delivery Systems and Devices)
In this study, we developed a microdevice concept for drug/fluidic transport taking an inspiration from supramolecular motor found in biological cells. Specifically, idealized multi-functional design geometry (nozzle/diffuser/nozzle) was developed for (i) fluidic/particle transport; (ii) particle separation; and (iii) droplet generation. Several design simulations were conducted to demonstrate the working principles of the multi-functional device. The design simulations illustrate that the proposed design concept is feasible for multi-functionality. However, further experimentation and optimization studies are needed to fully evaluate the multifunctional device concept for multiple applications. View Full-Text
Keywords: molecular motors; drug delivery; computer-aided-design; analysis; simulation molecular motors; drug delivery; computer-aided-design; analysis; simulation
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MDPI and ACS Style

Pidaparti, R.M.; Cartin, C.; Su, G. Bio-Inspired Multi-Functional Drug Transport Design Concept and Simulations. Bioengineering 2017, 4, 37.

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